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Acute Myocardial Infarction Therapy Market Trends 2025 | Innovative Cardiac Therapies & Biomarker Advances

08-01-2025 02:30 PM CET | Health & Medicine

Press release from: DataM Intelligence 4Market Research LLP

Acute Myocardial Infarction Market

Acute Myocardial Infarction Market

The Acute Myocardial Infarction (AMI) Treatment Market is witnessing steady growth, driven by the rising prevalence of cardiovascular diseases, an aging population, and significant advancements in minimally invasive and personalized therapies. The global AMI market reached approximately US$1.79 billion in 2024 and is forecasted to expand to US$3.07 billion by 2033, growing at a CAGR of 6.7% during 2025-2033. Key factors fuelling this growth include increasing rates of obesity and diabetes, growing demand for minimally invasive cardiac procedures, and investments in regenerative medicine such as gene and stem cell therapies aimed at heart repair.

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Prominent pharmaceutical companies actively shaping the AMI treatment landscape include Bayer, Novartis, Daiichi Sankyo, Boehringer Ingelheim, AstraZeneca, Janssen Biotech, Merck, Sanofi, and Pfizer. These industry leaders are committed to innovation and expanding treatment options for AMI patients worldwide. North America holds the largest share of the AMI market, benefiting from high cardiovascular disease prevalence and sophisticated healthcare infrastructure.

Recent Strategic Partnerships and Acquisitions Shaping the Acute Myocardial Infarction (AMI) Market

• Boditech Med's Investment in 4TEEN4 Pharmaceuticals: Boditech Med acquired a minority stake (3.03%) in 4TEEN4 Pharmaceuticals GmbH, focusing on diagnostics and therapies for AMI shock. Along with the investment, Boditech Med signed a licensing agreement to develop and commercialize 4TEEN4's diagnostic biomarker portfolio, including Procizumab, a DPP3 inhibitor aimed at reducing AMI shock and mortality.

• Indorsia and Viatris R&D Partnership: Indorsia entered a global research and development collaboration with Viatris to advance and commercialize Phase III assets selatogrel and cenerimod, targeting AMI and related cardiovascular diseases. The partnership includes upfront payments and tiered royalties.

• Philip Morris International's (PMI) Acquisition of OtiTopic: PMI acquired OtiTopic, a company specializing in inhalable acetylsalicylic acid (ASA) treatments designed to enhance drug delivery speed and patient outcomes for AMI care, strengthening the portfolio of inhaled therapies.

• Emerging Collaborations for Novel Therapeutics: Companies like Recardio have forged partnerships beyond the US and Europe to engage in Phase III clinical trials of innovative AMI drugs such as dutogliptin, expanding global development efforts.

Key Technological and Therapeutic Advances in 2025 AMI Treatment

• Early Revascularization: Primary percutaneous coronary intervention (PCI) remains the preferred treatment for ST-elevation myocardial infarction (STEMI) when performed within 12 hours of symptom onset, ideally via the radial artery to minimize complications. If PCI is not feasible, fibrinolytic therapy is promptly initiated. Intracoronary imaging tools like optical coherence tomography increasingly guide PCI for optimal stent placement.

• Antiplatelet Therapy: Dual antiplatelet therapy (DAPT), combining aspirin with a P2Y12 inhibitor such as ticagrelor or prasugrel, is the standard of care. Ticagrelor is generally preferred due to its enhanced efficacy and safety profile. For patients at higher bleeding risk, a shorter DAPT duration followed by ticagrelor monotherapy is now a recommended approach.

• Anticoagulation: During PCI, unfractionated heparin or bivalirudin is commonly utilized to prevent thrombus formation. Post-MI anticoagulation is guided by patient risk profiles, especially for those with left ventricular thrombus or atrial fibrillation.

• Beta-Blockers and ACE Inhibitors: Early administration of beta-blockers within 12 hours helps reduce myocardial oxygen demand and arrhythmia risk. ACE inhibitors are recommended early for patients with anterior MI, left ventricular dysfunction, or heart failure to prevent adverse cardiac remodeling.

• Mechanical Circulatory Support: In cases of cardiogenic shock, the use of devices such as microaxial flow pumps may be appropriate, though careful patient selection is needed due to potential complications like bleeding or limb ischemia.

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Key Regional Growth Drivers Influencing the Acute Myocardial Infarction (AMI) Market in 2025

North America: The region leads the AMI treatment market due to its advanced healthcare systems, high healthcare spending, and broad availability of diagnostics and therapeutics. The large elderly population, coupled with increasing cardiovascular disease prevalence, sustains demand for innovative treatments, including antiplatelet agents, thrombolytics, beta-blockers, as well as emerging regenerative medicine approaches like gene and stem cell therapies.

Europe: Europe holds a significant share, underpinned by well-established healthcare frameworks, strong cardiovascular prevention programs, and government-backed support for early intervention. The region embraces innovative treatments, including RNA therapeutics and novel antithrombotic drugs. Countries such as Germany, the UK, and France benefit from supportive regulations, an aging demographic, and a persistently high burden of cardiovascular disease.

Asia Pacific: Set to be the fastest-growing region, Asia Pacific's market expansion is driven by rising rates of cardiovascular risk factors, such as obesity and diabetes, alongside investments to broaden healthcare infrastructure and improve access to diagnostics and minimally invasive treatments. Key markets like China, India, Japan, and Southeast Asian nations are at the forefront of increasing healthcare expenditure and personalized medicine adoption, facilitating rapid growth.

Latin America and Middle East & Africa: These emerging markets are characterized by improving healthcare infrastructure, growing awareness of cardiovascular disease, and expanding access to essential therapies. Despite challenges, including affordability and lower early diagnosis rates, government efforts and expanding hospital networks are fostering steady market growth. Gradual uptake of guideline-backed therapies and advances in emergency cardiac care devices are also contributing to progress.

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