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2025-2034 Peptide Synthesis Market Outlook: Key Drivers, Emerging Challenges, and Strategic Insights

07-30-2025 01:19 PM CET | Health & Medicine

Press release from: The Business Research Company

Peptide Synthesis Market

Peptide Synthesis Market

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What Will the Peptide Synthesis Industry Market Size Be by 2025?
The peptide synthesis industry has experienced significant growth in its market size in recent years. This growth is projected to continue as the market is expected to increase from $5.69 billion in 2024 to $6.19 billion in 2025, reflecting a compound annual growth rate (CAGR) of 8.8%. Factors contributing to growth in the historical period include an increase in peptide-based vaccines, development in biotechnology and biopharmaceuticals, a rise in demand for high-purity peptides, regulatory sanctions, and standardization.

What's the Long-Term Growth Forecast for the Peptide Synthesis Market Size Through 2029?
The market for peptide synthesis is predicted to experience robust expansion in the coming years, with expectations that it will reach a size of $8.9 billion by 2029, reflective of a compound annual growth rate (CAGR) of 9.5%. This anticipated growth during the forecast period is associated with the swift expansion of therapeutic peptides, spiraling demand for customized peptides, their increasing significance in drug discovery and development, and emphasis on peptide libraries for screening processes. Key trends projected to shape the market during the forecast period are the creation of peptide mimetics, the uptake of new amino acid derivatives, the use of techniques for peptide cyclization, advancements in solid-phase peptide synthesis (SPPs), and the application of click chemistry.

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What Are the Key Growth Drivers Fueling the Peptide Synthesis Market Expansion?
The escalating prevalence of chronic diseases is anticipated to fuel the expansion of the peptide synthesis market. Chronic ailments, which are essentially non-communicable, long-lasting health issues that typically develop slowly over time, have shown a significant rise. Peptide synthesis proves beneficial in tackling these chronic diseases as certain peptides display anti-inflammatory and antioxidant effects that can potentially aid in preventing conditions like cardiovascular diseases. By targeting specific cellular procedures and signaling pathways, peptides can address the underlying origins of chronic diseases, introducing innovative treatment and management alternatives. For instance, data provided by the Australian Institute of Health and Welfare, a government agency located in Australia, revealed that the age-standardized rate of deaths due to chronic conditions increased from 459 per 100,000 population in 2021 to 490 per 100,000 in 2022. Therefore, the rising prevalence of chronic diseases is propelling the peptide synthesis market's growth. Peptide Synthesis Market Driver: Surge in Healthcare Expenses Propels Growth of Peptide Synthesis Market

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What Are the Key Trends Driving Peptide Synthesis Market Growth?
Top-tier firms active in the peptide synthesis market are shifting their focus towards launching state-of-the-art peptide synthesizers like PurePep Sonata+ to maintain competitiveness. This advanced synthesizer offers enhanced speed, efficiency, and precision compared to conventional peptide synthesizers. For instance, in March 2022, Gyros Protein Technologies, an American peptide synthesis and bioanalytical technology service provider, launched the PurePep Sonata+ synthesizer. The PurePep Sonata+ enhances the functionality of the Sonata XT by adopting real-time flow technology, offering ongoing fluid flow rate monitoring within the system. This groundbreaking method provides a non-intrusive way to assure accurate fluid transfers across a range of viscosities.

How Is the Peptide Synthesis Market Segmented?
The peptide synthesis market covered in this report is segmented -

1) By Product And Service: Reagents, Equipment, Services
2) By Technology: Solid-Phase Peptide Synthesis, Solution-Phase Peptide Synthesis, Hybrid And Recombinant Technology
3) By End User: Pharmaceutical And Biotechnology companies, Contract Manufacturing And Development Organizations (CDMOs) And Contract Research Organizations (CROs), Academic And Research Institutes

Subsegments:
1) By Reagents: Amino Acids, Coupling Reagents, Protecting Groups, Cleavage Reagents
2) By Equipment: Peptide Synthesizers, Chromatography Systems, Mass Spectrometers, Other Analytical Instruments
3) By Services: Custom Peptide Synthesis, Peptide Characterization And Analysis, Peptide Modification Services, Consulting And Support Services

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Which Companies Are Leading the Charge in Peptide Synthesis Market Innovation?
Major companies operating in the peptide synthesis market report are Thermo Fisher Scientific, Novo Nordisk A/S, Merck KGaA, Lonza Group, Kaneka Corporation, Uno Minda, Guizhou Xinbang Pharmaceutical Co. Ltd., Hybio Pharmaceutical Co. Ltd., GenScript Biotech, Bachem Holding AG, Syngene International, PolyPeptide Group AG, Mesa Labs Inc., CPC Scientific Inc., New England Peptide Inc., Biotage, ScinoPharm Taiwan Ltd., MP Biomedicals, USV Private Limited, CEM Corporation, Enamine Ltd., Creative Diagnostics, AnaSpec Inc., CSBio Company Inc., Alfa Chemistry, Advanced ChemTech, Gyros Protein Technologies AB, AAPPTec LLC, Biosynth International Inc., ProteoGenix

Which Regions Are Leading the Global Peptide Synthesis Market in Revenue?
North America was the largest region in the peptide synthesis market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the peptide synthesis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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Peptide Modifications For PEGylation
PEGylation is the process of covalently attaching polyethylene glycol (PEG) polymer chains to peptides. By increasing their molecular mass and shielding them from proteolytic enzymes, PEGylation improves the pharmacokinetics of peptides and proteins. PEGylation reduces renal clearance and results in more sustained absorption after subcutaneous administration, as well as restricted distribution. PEGylations have been shown to significantly improve water solubility, biocompatibility, immunogenicity, and other physico-chemical properties. It is an established