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2025 Antisense & RNAi Therapeutics Industry Trends Report: Long-Term Outlook Through 2034

07-14-2025 01:58 PM CET | Health & Medicine

Press release from: The Business Research Company

Antisense & RNAi Therapeutics

Antisense & RNAi Therapeutics

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How Large Will the Antisense & RNAi Therapeutics Market Size By 2025?
There has been a swift expansion in the antisense & RNAi therapeutics market in the past few years. The market value, which was $1.75 billion in 2024, is predicted to escalate to $1.94 billion in 2025, presenting an impressive compound annual growth rate (CAGR) of 11.2%. The substantial growth witnessed in the historic time frame can be credited to the surge in funding, technological advancements, increase in healthcare spending, acceleration in the growth of the elderly populace, and upward economic trends in growing markets.

How Big Is the Antisense & RNAi Therapeutics Market Size Expected to Grow by 2029?
In the coming years, the antisense & RNAi therapeutics market is projected to experience swift expansion, reaching $3.18 billion by 2029 with a compound annual growth rate (CAGR) of 13.1%. The predicted growth during the forecast period can be ascribed to improved access to healthcare, increasing cancer prevalence, and the rising demand for antisense and RNAi therapeutics due to the COVID-19 pandemic. The forecast period also sees major trends such as concentrated efforts on research and development of RNA therapeutics for rare diseases, utilization of nanoparticles, and the development of enhanced antisense and RNAi therapeutics. Collaborations with other firms for product innovation and revenue generation will also be a key trend.

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Which Key Market Drivers Powering Antisense & RNAi Therapeutics Market Expansion and Growth?
The antisense & RNAi therapeutics market is expected to see increased demand due to a surge in the incidence of coronary artery diseases, neurodegenerative illnesses, and infectious ailments. Gene silencing techniques, such as RNA interference and antisense oligonucleotides, are employed to fix mutant genes and manage a variety of neurodegenerative conditions. As an illustration, a report from the American Heart Association, a renowned US organization, indicated that as of January 2024, the age-adjusted death rate from cardiovascular diseases spiked to 233.3 per 100,000, marking a 4.0% increase from the preceding year. Consequently, the rise in the occurrence of various neurodegenerative and infectious diseases is anticipated to fuel the expansion of the antisense & RNAi therapeutics market.

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Which Fast-Growing Trends Are Poised to Disrupt the Antisense & RNAi Therapeutics Market?
Key players in the antisense & RNAi therapeutics market are employing strategic moves such as forming collaborations and partnerships to keep their footing in a progressively competitive environment. This strategic cooperation is a business tactic that sees multiple businesses collaborate to reach a shared purpose or aim. For instance, in January 2023, US-based Orbit Discovery Limited, a firm that provides services for the discovery of peptides, established a partnership with SanegeneBio Inc., a UK-based firm known for developing unique RNAi-based medicines. The aim of this partnership is to identify tissue-specific distributions of therapeutics for efficient gene knockdown, as well as to cultivate a collection of enhanced RNAi therapeutics. The partnership will include hit identification and cell-based internalization studies, and SanegeneBio will have the choice to further develop hits that derive from the screening actions. These developments will utilize Orbit's exclusive technology for swift peptide lead discovery. The distinctive peptide display engine of Orbit Discovery facilitates the examination of large peptide libraries, thus providing quicker detection times for appropriate peptide leads relying on affinity and functional screens.

What Are the Emerging Segments in the Antisense & RNAi Therapeutics Market?
The antisense & RNAi therapeutics market covered in this report is segmented -

1) By Technology: RNA Interference, Antisense RNA
2) By Route Of Administration: Intravenous Injections, Intra-dermal Injections, Other Delivery Methods
3) By Indication: Oncology, Cardiovascular Diseases (CVDs), Respiratory Disorders, Neurological Disorders, Infectious Diseases, Other Indications

Subsegments:
1) By RNA Interference (RNAi): Small Interfering RNA (siRNA), Short Hairpin RNA (shRNA), Dicer-substrate siRNA, MicroRNA (miRNA) Based Therapeutics
2) By Antisense RNA: Antisense Oligonucleotides (ASOs), Morpholino Oligomers, Locked Nucleic Acids (LNAs), Gapmer Antisense Oligonucleotides

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Who Are the Global Leaders in the Antisense & RNAi Therapeutics Market?
Major companies operating in the antisense & RNAi therapeutics market include Biogen Inc., Ionis Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc., Arrowhead Pharmaceuticals Inc., Moderna Inc., Sanofi S.A., Dicerna Pharmaceuticals Inc., Arbutus Biopharma Corporation, Acuitas Therapeutics, Adhera Therapeutics Inc., EdiGene Inc., Sirnaomics Inc., Suzhou Ribo Life Science Co. Ltd, Biocon Limited, Quark Pharmaceuticals, GlaxoSmithKline Plc, Shanghai Junshi Biosciences Co. Ltd., AstraZeneca, Benitec Biopharma Limited, Silence Therapeutics, Dynacure, CN Bio Innovations, Sarepta Therapeutics, Mallinckrodt, Regeneron Pharmaceuticals Inc., Alcyone Lifesciences Inc., Bio-Path Holdings Inc, Calando Pharmaceuticals, Enzon Pharmaceuticals Inc, Celnova Pharma, Pfizer Inc., Taiba Pharma, Gen Ilaç ve Saglik Ürünleri A.S., Egypt Otsuka Pharmaceutical

Which are the Top Profitable Regional Markets for the Antisense & RNAi Therapeutics Industry?
North America was the largest region in the antisense & RNAi therapeutics market in 2024. The regions covered in the antisense & RNAi therapeutics market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

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