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Global Low-Grade Glioma Market Outlook 2025-2034: Trends, Innovations, And Future Outlook

06-17-2025 07:18 AM CET | Health & Medicine

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Low-Grade Glioma Market

Low-Grade Glioma Market

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What Is the Low-Grade Glioma Market Size and Projected Growth Rate?
The market size for low-grade glioma has seen vigorous growth in the past years. The market is predicted to expand from $1.39 billion in 2024 to $1.48 billion in 2025, with a compound annual growth rate (CAGR) of 6.1%. Factors such as heightened awareness about brain tumors, a surge in oncology research funding, a rise in the designation of orphan drugs, telemedicine expansion, and enhanced healthcare access contributed to the growth over the historic period.

Expectations are high for significant expansion in the low-grade glioma market size over the coming years. It's projected to reach $1.86 billion by 2029, boasting a compound annual growth rate (CAGR) of 5.9%. This growth is attributed to a multitude of factors such as an increasing aged population, expanded healthcare spending, a rise in brain tumor incidences, growing government initiatives, and a surge in high-grade gliomas prevalence. The forecast period is also expected to witness several major trends, including breakthroughs in imaging technologies, the refinement of radiation therapies, the introduction of new chemotherapy regimens, a broader scope of clinical trials, and greater incorporation of immunotherapy.

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What Are the Major Segments in the Low-Grade Glioma Market?
The low-grade glioma market covered in this report is segmented -

1) By Drug Type: Trametinib, Dabrafenib, Ivosidenib, Mirdametinib
2) By Treatment: Surgery, Chemotherapy, Radiation
3) By Route Of Administration: Topical, Oral
4) By Distribution Channel: Online Pharmacies, Hospital Pharmacies, Retail Pharmacies

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What Are The Driving Low-Grade Glioma Market Evolution?
The surge in brain tumor cases is anticipated to fuel the expansion of the low-grade glioma market. Brain tumors, which can be benign or malignant, are unusual cell growths in the brain or nearby regions. This increase in brain tumors is attributed to reasons such as escalated contact with radiation, environmental pollutants, genetic factors, and aging. Using specialized diagnostic techniques and specific treatments like surgery, radiation, and chemotherapy, low-grade glioma addresses brain tumors. These treatments slow the growth of the tumor, conserve neurological function, and better patient results, underlining the importance of early diagnosis and individualized treatment in managing other brain tumors with comparable growth patterns. For example, per the Central Brain Tumor Registry of the United States (CBTRUS), a non-profit organization based in the US, it was reported in October 2023 that the global prevalence of primary malignant brain tumors in 2022 was about 3.5 per 100,000, with elevated rates in wealthier nations (4.9 per 100,000) than in lower-middle income (2.4 per 100,000) and poorer nations. Hence, the increasing incidence of brain tumors is propelling the growth of the low-grade glioma market.

Which Firms Dominate The Low-Grade Glioma Market Segments?
Major companies operating in the low-grade glioma market are McKesson Corporation, F. Hoffmann-La Roche Ltd, Merck & Co. Inc., Bristol-Myers Squibb Company, AstraZeneca PLC, Novartis AG, Daiichi Sankyo Company Limited, Ipsen S.A., BeiGene Ltd., NovoCure Limited, Les Laboratoires Servier, Day One Biopharmaceuticals Inc., CStone Pharmaceuticals Co. Ltd., AnHeart Therapeutics Inc., Apollomics Inc., Agios Pharmaceuticals Inc., BioMed Valley Discoveries Inc., Avistone Biotechnology Co. Ltd., NextSource Biotechnology LLC, Sunesis Pharmaceuticals Inc.

What Are the Major Trends Shaping the Low-Grade Glioma Market?
Leading players in the low-grade glioma market are strategizing to incorporate a combination of therapies and targeted treatment, like genetic alteration medicines, to not only maintain their market position but also to improve care for children diagnosed with low-grade glioma. Genetic alteration medicines refer to targeted treatments engineered to either change or inhibit certain genetic mutations or abnormalities within cells, aiding in the treatment of illnesses such as cancer by interfering with the growth pathways of uncontrolled cells. For instance, Day One Biopharmaceuticals, an American biotech firm, introduced Tovorafenib (Ojemda) in May 2024 after securing fast-tracked FDA approval. This therapy, tailored for children starting from the age of six months who are diagnosed with inoperable or recurrent low-grade glioma (LGG) with BRAF gene alterations, is administered orally once a week, thus fulfilling a crucial therapeutic gap for pediatric LGG patients who have previously had limited treatment choices.

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Which Is The Largest Region In The Low-Grade Glioma Market?
North America was the largest region in the low-grade glioma market in 2024. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the low-grade glioma market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Low-Grade Glioma Market?
2. What is the CAGR expected in the Low-Grade Glioma Market?
3. What Are the Key Innovations Transforming the Low-Grade Glioma Industry?
4. Which Region Is Leading the Low-Grade Glioma Market?

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