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AL Amyloidosis Market Report 2025-2034: Industry Overview, Trends, And Forecast Analysis
AL Amyloidosis Market Size
What Is the Current AL Amyloidosis Market Size and Its Estimated Growth Rate?
The market size of AL amyloidosis has seen a swift increase in the past few years. It's anticipated to escalate from $3.11 billion in 2024 to $3.52 billion in 2025, showcasing a compound annual growth rate (CAGR) of 13.2%. The historic progression in the market size can be accredited to the heightened awareness about AL amyloidosis amongst healare professionals, an increasing frequency of AL amyloidosis cases, growth in the elderly population, the development of diagnostic centers, and advancements in cardiac imaging.
In the coming years, the market size of AL amyloidosis is projected to experience swift expansion. It is predicted to surge to $5.74 billion by 2029, with a compound annual growth rate (CAGR) of 13.0%. The upswing for the projected period can be ascribed to an increase in mutation instances in blood cell DNA, enhancing healare infrastructure, a rising rate of multiple myeloma, the implementation of combination therapies, and the escalated use of high-dose chemotherapy. Major trends aligned for the forecast period incorporate progression in diagnostic methodologies, technological enhancements in drug distribution, improvements in blood examinations, the creation of targeted therapies, and the integration of artificial intelligence (AI) in diagnostic procedures.
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How Are Emerging Segments Shaping the AL Amyloidosis Market Landscape?
The AL amyloidosis market covered in this report is segmented -
1) By Treatment: Chemotherapy, Supportive Care, Surgery, Stem Cell Transplant, Targeted Therapy
2) By Drugs: Transthyretin Transport Inhibitor, Immunomodulatory Drugs, Monoclonal Antibodies, Proteasome Inhibitors, Other Drugs
3) By Route Of Administration: Intravenous, Oral
4) By Distribution Channel: Hospital Pharmacies, Retail Pharmacies, Online Pharmacies
Subsegments:
1) By Chemotherapy: Conventional Chemotherapy Agents, High-Dose Chemotherapy
2) By Supportive Care: Pain Management, Organ-specific Supportive Care (Cardiac, Renal)
3) By Surgery: Organ Transplantation, Debulking Surgery
4) By Stem Cell Transplant: Autologous Stem Cell Transplant, Allogeneic Stem Cell Transplant
5) By Targeted Therapy: Monoclonal Antibodies, Proteasome Inhibitors, Kinase Inhibitors
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Which Growth Factors Are Influencing AL Amyloidosis Market Expansion?
The increased prevalence of plasma cell disorders is projected to drive the growth of the AL amyloidosis market. Plasma cell disorders are diseases in which abnormal plasma cells create too many or abnormal antibodies, potentially inflicting damage to organs. The growing frequency of plasma cell disorders is credited to factors such as an elderly population, longer life expectancy, and progress in diagnostic technologies. AL amyloidosis arises from plasma cell disorders, particularly the overproduction of abnormal light chain proteins, which can result in the build-up of amyloid deposits in organs and tissues, further worsening the impact of plasma cell dyscrasias. For instance, in August 2024, as per the reports published by The American Cancer Society (ACS), a US-based non-profit organization, there will be around 35,780 new cases of multiple myeloma anticipated to be diagnosed (19,520 in men and 16,260 in women) in 2024, and about 12,540 deaths are estimated, with 7,020 in men and 5,520 in women. Therefore, the escalating prevalence of plasma cell disorders is fuelling the growth of the AL amyloidosis market.
Who Are the Dominant Players Across Different AL Amyloidosis Market Segments?
Major companies operating in the AL amyloidosis market are Johnson & Johnson, AbbVie Inc., Sanofi S.A., Bristol-Myers Squibb Company, AstraZeneca PLC, Takeda Pharmaceutical Company Limited, Boehringer Ingelheim International GmbH, Astellas Pharma Inc., Genmab A/S, Alexion Pharmaceuticals Inc., Alnylam Pharmaceuticals Inc., Prothena Corporation plc, BridgeBio Pharma Inc., Sorrento Therapeutics Inc., Ionis Pharmaceuticals Inc., Ultromics Ltd, Neurimmune AG, Immix Biopharma Inc., Oncopeptides AB, Attralus Inc.
What Are the Latest Developing Trends in the Acne Treatment Devices Market?
Key enterprises in the AL amyloidosis industry are concentrating on the creation of novel treatments like next-generation B-cell maturation antigen (BCMA)-directed CAR T-cell therapy, which offers improved therapeutic efficiency and patient prognosis. This next-generation therapy represents an advanced immunotherapy variant that involves modifying the patient's T cells to identify and combat BCMA found on cancer cells, particularly in multiple myeloma. For example, in September 2023, the U.S. Food and Drug Administration (FDA) granted approval to U.S. biopharmaceutical firm, Immix Biopharma Inc., for their NXC-201 application. This application was for the treatment of the potentially fatal blood condition Amyloid Light Chain (AL) Amyloidosis. Currently being tested in clinical trials, NXC-201 is a next-gen CAR-T cell therapy showing encouraging possibilities for AL amyloidosis treatment, with reports of a 100% hematologic response rate and organ function enhancement in patients unsuccessful with prior treatments.
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Which Geographic Regions Are Expected to Dominate the AL Amyloidosis Market in the Coming Years?
North America was the largest region in the AL amyloidosis market in 2024. The regions covered in the AL amyloidosis market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the AL Amyloidosis Market?
2. What is the CAGR expected in the AL Amyloidosis Market?
3. What Are the Key Innovations Transforming the AL Amyloidosis Industry?
4. Which Region Is Leading the AL Amyloidosis Market?
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