Press release
Checkpoint Inhibitors Market Size Projected To Reach $55.64 Billion By 2034 With A Cagr Of 10.1%
The Checkpoint Inhibitors Market Report by The Business Research Company delivers a detailed market assessment, covering size projections from 2025 to 2034. This report explores crucial market trends, major drivers and market segmentation by [key segment categories].What Is the Projected Growth of the Checkpoint Inhibitors Market?
The checkpoint inhibitors market has experienced rapid growth, expanding from $32.41 billion in 2024 to $37.88 billion in 2025 at a CAGR of 16.9%. The growth is attributed to the rising incidence of cancer, greater awareness of checkpoint inhibitors, a broader range of approved checkpoint inhibitors, research on novel inhibitors, and increasing clinical trials and studies.
The checkpoint inhibitors market is anticipated to experience rapid expansion, with its size projected to hit $55.64 billion by 2029, growing at a CAGR of 10.1%. This growth will be supported by new therapeutic uses, discoveries in biomarkers, personalized treatment approaches, and combined treatment strategies. Leading trends include advances in precision immunotherapy, immune checkpoint pairings, integration with cell therapies, biosimilar developments, and immunotherapy combinations.
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What Are the Different Checkpoint Inhibitors Market Segments?
The checkpoint inhibitors market covered in this report is segmented -
1) By Drug: PD-1 Inhibitors, PD-L1 Inhibitors, CTLA-4, Chimeric Antigen Receptor T-cell, Other Drugs
2) By Application: Lung Cancer, Renal Cancer, Blood Cancer, Bladder Cancer, Melanoma, Other Applications
3) By End-Users: Hospitals Pharmacies, Retail Pharmacies, Online Pharmacies
Subsegments:
1) By PD-1 Inhibitors: Pembrolizumab (Keytruda), Nivolumab (Opdivo)
2) By PD-L1 Inhibitors: Atezolizumab (Tecentriq), Durvalumab (Imfinzi), Avelumab (Bavencio)
3) By CTLA-4: Ipilimumab (Yervoy)
4) By Chimeric Antigen Receptor T-cell: CAR T-cell Therapy Products
5) By Other Drugs: Combination Therapies, Emerging Checkpoint Inhibitors
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What Are the Primary Drivers Shaping the Checkpoint Inhibitors Market?
Increasing global cancer incidence is expected to boost the checkpoint inhibitors market. Cancer cases are rising due to aging populations, poor lifestyle habits, and environmental and genetic factors. Checkpoint inhibitors help immune cells recognize and destroy cancer. As of September 2024, the American Cancer Society projected cancer cases in men to rise by 84% to 19 million by 2050, with deaths increasing by 93% to 10.5 million, which supports the market's expansion.
Which Companies Are Leading in the Checkpoint Inhibitors Market?
Major companies operating in the checkpoint inhibitors market include AstraZeneca plc, Bristol-Myers Squibb Company, Merck & Co. Inc., Roche Holding AG, Pfizer Inc., Incyte Corporation, Novartis AG, GlaxoSmithKline plc, Innate Pharma S.A., Ono Pharmaceutical Co. Ltd., Eli Lilly and Company, Sanofi S.A, AbbVie Inc., Amgen Inc., Astellas Pharma Inc., Bayer AG, Boehringer Ingelheim International GmbH, Celgene Corporation, Daiichi Sankyo Company Limited, Eisai Co. Ltd., Gilead Sciences Inc., Kyowa Kirin Co. Ltd., Johnson & Johnson, Regeneron Pharmaceuticals Inc., Takeda Pharmaceutical Company Limited, Zai Lab Limited
What Are the Latest Developing Trends in the Checkpoint Inhibitors Market?
Leading companies in the checkpoint inhibitor market are developing advanced technologies like oral checkpoint inhibitors. These inhibitors are designed for oral use to block immune checkpoints like PD-1/PD-L1, helping the immune system recognize and fight cancer. For example, OmRx Oncology, a US-based biopharmaceutical firm, launched OX-4224 in September 2024, an oral checkpoint inhibitor targeting PD-1/PD-L1 for non-small cell lung cancer (NSCLC). This drug aims to provide a more affordable option to biologic checkpoint inhibitors and improve global access to cancer immunotherapy. OmRx is also conducting a Phase 2 study in India to test its safety and efficacy.
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What Are the Top Revenue-Generating Geographies in the Checkpoint Inhibitors Market?
The countries covered in the checkpoint inhibitors market report are Australia, Brazil, China, France, Germany, India, Indonesia, Japan, Russia, South Korea, UK, USA, Italy, Spain, Canada.
Frequently Asked Questions:
1. What Is the Market Size and Growth Rate of the Checkpoint Inhibitors Market?
2. What is the CAGR expected in the Checkpoint Inhibitors Market?
3. What Are the Key Innovations Transforming the Checkpoint Inhibitors Industry?
4. Which Region Is Leading the Checkpoint Inhibitors Market?
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Report Table of Contents
Immune Checkpoint Inhibitors- Introduction to Next Generation Cancer Immunotherapy
1.1 Overview
1.2 History- From Tragedy to Breakthrough
Major Immune Checkpoints Proteins
2.1 Role of Cytotoxic T lymphocyte Antigen-4 (CTLA-4) in Cancer Development
2.2 Role of Programed Cell Death Protein 1 (PD1) in Cancer Development
Mechanism of Action of Immune Checkpoint Inhibitors
3.1 Cytotoxic T lymphocyte Antigen-4…