PD-1 and PD-L1 Inhibitors Competitor Landscape 2025: Therapies, MOA Insights, and Key Clinical Trial Updates by DelveInsight | Compass Therapeutics, Aurigene Discovery Technologies, RemeGen, Aurigene Discovery Technologies

(Las Vegas, Nevada, United States) As per DelveInsight's assessment, globally, PD-1 and PD-L1 Inhibitors pipeline constitutes 180+ key companies continuously working towards developing 200+ PD-1 and PD-L1 Inhibitors treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"PD-1 and PD-L1 Inhibitors Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the PD-1 and PD-L1 Inhibitors Market.

The PD-1 and PD-L1 Inhibitors Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

Some of the key takeaways from the PD-1 and PD-L1 Inhibitors Pipeline Report: https://www.delveinsight.com/sample-request/pd-1-and-pd-l1-inhibitors-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr
• Companies across the globe are diligently working toward developing novel PD-1 and PD-L1 Inhibitors treatment therapies with a considerable amount of success over the years.
• PD-1 and PD-L1 Inhibitors companies working in the treatment market are Compass Therapeutics, Aurigene Discovery Technologies, RemeGen, Aurigene Discovery Technologies, Inhibrx, Effector Therapeutics, CytomX Therapeutics, Innovent Biologics, GlaxoSmithKline, Biocad, Genentech, Bristol Myers Squibb, Merck, and others, are developing therapies for the PD-1 and PD-L1 Inhibitors treatment
• Emerging PD-1 and PD-L1 Inhibitors therapies such as - CTX-8371, CA 327, RC-98, AUR-106, INBRX 105, Tomivosertib, CX-072, IBI 323, Jemperli, BCD-100, TECENTRIQ, Opdivo, KEYTRUDA, and others are expected to have a significant impact on the PD-1 and PD-L1 Inhibitors market in the coming years.
• In May 2025, Clinical-stage biopharma company OmRx Oncology (OmRx) has launched a randomized Phase II trial for its oral PD-L1 inhibitor, OX-4224, aimed at patients with non-small cell lung cancer (NSCLC). The company believes this investigational small molecule could provide a more affordable and accessible alternative to current antibody-based treatments. The open-label study plans to enroll around 50 metastatic NSCLC patients, primarily in India, who have not previously received immune checkpoint inhibitor therapies. OX-4224 will be assessed as a second-line monotherapy in this patient population.
• In March 2025, Actinium Pharmaceuticals, Inc. (NYSE AMERICAN: ATNM), a leader in targeted radiotherapies, has announced a new clinical program featuring trials of Actimab-A combined with either KEYTRUDA® (pembrolizumab) or OPDIVO® (nivolumab). These blockbuster PD-1 inhibitors, developed by Merck & Co. and Bristol Myers Squibb respectively, together generated $38.8 billion in sales in 2024 across multiple solid tumor indications. Despite their success, their effectiveness is often limited by Myeloid Derived Suppressor Cells (MDSCs), which accumulate in the tumor microenvironment and express the CD33 antigen - the specific target of Actimab-A. The trials aim to explore whether depleting MDSCs with Actimab-A can enhance the efficacy of these immunotherapies.
• In January 2025, ImmunityBio, Inc. (NASDAQ: IBRX) announced a new collaboration and supply agreement with BeiGene, Ltd. (soon to be renamed BeOne Medicines, Ltd.), a global oncology company, to conduct a pivotal randomized Phase 3 trial (ResQ201A-NSCLC). This trial will combine BeiGene's PD-1 checkpoint inhibitor, tislelizumab, with ImmunityBio's ANKTIVA (nogapendekin alfa inbakicept-pmln). The ResQ201A-NSCLC study (NCT06745908) aims to validate the efficacy and safety of this combination, previously shown in the QUILT 3.055 trial, and provide evidence that these two immunotherapies can enhance overall survival in patients with advanced or metastatic NSCLC who have developed resistance to immune CPI treatments.

PD-1 and PD-L1 Inhibitors Overview
PD-1 (programmed cell death protein 1) is found on the surface of cancer cells. It is used by tumors to evade the immune system so blocking its action enables the body to attack and kill cancer. T cells constantly monitor our body for abnormal cells and eliminate them before they can turn into cancer

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Emerging PD-1 and PD-L1 Inhibitors Drugs Under Different Phases of Clinical Development Include:
• CTX-8371: Compass Therapeutics
• CA 327: Aurigene Discovery Technologies
• RC-98: RemeGen
• AUR-106: Aurigene Discovery Technologies
• INBRX 105: Inhibrx
• Tomivosertib: Effector Therapeutics
• CX-072: CytomX Therapeutics
• IBI 323: Innovent Biologics
• Jemperli: GlaxoSmithKline
• BCD-100: Biocad
• TECENTRIQ: Genentech
• Opdivo: Bristol Myers Squibb
• KEYTRUDA: Merck

PD-1 and PD-L1 Inhibitors Pipeline Therapeutics Assessment
• PD-1 and PD-L1 Inhibitors Assessment by Product Type
• PD-1 and PD-L1 Inhibitors By Stage and Product Type
• PD-1 and PD-L1 Inhibitors Assessment by Route of Administration
• PD-1 and PD-L1 Inhibitors By Stage and Route of Administration
• PD-1 and PD-L1 Inhibitors Assessment by Molecule Type
• PD-1 and PD-L1 Inhibitors by Stage and Molecule Type

DelveInsight's PD-1 and PD-L1 Inhibitors Report covers around 200+ products under different phases of clinical development like
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further PD-1 and PD-L1 Inhibitors product details are provided in the report. Download the PD-1 and PD-L1 Inhibitors pipeline report to learn more about the emerging PD-1 and PD-L1 Inhibitors therapies
https://www.delveinsight.com/sample-request/pd-1-and-pd-l1-inhibitors-competitive-landscape?utm_source=openpr&utm_medium=pressrelease&utm_campaign=gpr

Some of the key companies in the PD-1 and PD-L1 Inhibitors Therapeutics Market include:
Key companies developing therapies for PD-1 and PD-L1 Inhibitors are - F. Hoffmann-La Roche AG, Sanofi S.A., Amgen Inc., AstraZeneca PLC, Pfizer Inc., Bristol-Myers Squibb Company, Others.

PD-1 and PD-L1 Inhibitors Pipeline Analysis:
The PD-1 and PD-L1 Inhibitors pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of PD-1 and PD-L1 Inhibitors with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for PD-1 and PD-L1 Inhibitors Treatment.
• PD-1 and PD-L1 Inhibitors key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• PD-1 and PD-L1 Inhibitors Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the PD-1 and PD-L1 Inhibitors market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

Download Sample PDF Report to know more about PD-1 and PD-L1 Inhibitors drugs and therapies
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PD-1 and PD-L1 Inhibitors Pipeline Market Drivers
• Rise in prevalence of Cancer, PD-1 and PD-L1 Inhibitors are emerging as an important checkpoint inhibitors used as frontline treatment in various cancer are some of the important factors that are fueling the PD-1 and PD-L1 Inhibitors Market.

PD-1 and PD-L1 Inhibitors Pipeline Market Barriers
• However, high cost associated with the treatment, side effects associated with the treatment and other factors are creating obstacles in the PD-1 and PD-L1 Inhibitors Market growth.

Scope of PD-1 and PD-L1 Inhibitors Pipeline Drug Insight
• Coverage: Global
• Key PD-1 and PD-L1 Inhibitors Companies: Compass Therapeutics, Aurigene Discovery Technologies, RemeGen, Aurigene Discovery Technologies, Inhibrx, Effector Therapeutics, CytomX Therapeutics, Innovent Biologics, GlaxoSmithKline, Biocad, Genentech, Bristol Myers Squibb, Merck, and others
• Key PD-1 and PD-L1 Inhibitors Therapies: CTX-8371, CA 327, RC-98, AUR-106, INBRX 105, Tomivosertib, CX-072, IBI 323, Jemperli, BCD-100, TECENTRIQ, Opdivo, KEYTRUDA, and others
• PD-1 and PD-L1 Inhibitors Therapeutic Assessment: PD-1 and PD-L1 Inhibitors current marketed and PD-1 and PD-L1 Inhibitors emerging therapies
• PD-1 and PD-L1 Inhibitors Market Dynamics: PD-1 and PD-L1 Inhibitors market drivers and PD-1 and PD-L1 Inhibitors market barriers

Request for Sample PDF Report for PD-1 and PD-L1 Inhibitors Competitive Assessment and clinical trials
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Table of Contents
1 PD-1 and PD-L1 Inhibitors Report Introduction
2 PD-1 and PD-L1 Inhibitors Executive Summary
3 PD-1 and PD-L1 Inhibitors Overview
4 PD-1 and PD-L1 Inhibitors- Analytical Perspective In-depth Commercial Assessment
5 PD-1 and PD-L1 Inhibitors Pipeline Therapeutics
6 PD-1 and PD-L1 Inhibitors Late Stage Products (Phase II/III)
7 PD-1 and PD-L1 Inhibitors Mid Stage Products (Phase II)
8 PD-1 and PD-L1 Inhibitors Early Stage Products (Phase I)
9 PD-1 and PD-L1 Inhibitors Preclinical Stage Products
10 PD-1 and PD-L1 Inhibitors Therapeutics Assessment
11 PD-1 and PD-L1 Inhibitors Inactive Products
12 Company-University Collaborations (Licensing/Partnering) Analysis
13 PD-1 and PD-L1 Inhibitors Key Companies
14 PD-1 and PD-L1 Inhibitors Key Products
15 PD-1 and PD-L1 Inhibitors Unmet Needs
16 PD-1 and PD-L1 Inhibitors Market Drivers and Barriers
17 PD-1 and PD-L1 Inhibitors Future Perspectives and Conclusion
18 PD-1 and PD-L1 Inhibitors Analyst Views
19 Appendix
20 About DelveInsight
*The Table of Contents (TOC) is not exhaustive; the final content may vary. Refer to the sample report for the complete table of contents.

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