Vascular Dementia Market forecast 2034: EMA, PDMA, FDA Approvals, Medication, Clinical Trials, Prevalence, Statistics, Revenue, Therapies, Treatment, Companies by DelveInsight

(Albany, USA) DelveInsight's 'Vascular Dementia Market Insights, Epidemiology, and Market Forecast-2034' report delivers an in-depth understanding of the Vascular Dementia, historical and forecasted epidemiology as well as the Vascular Dementia market trends in the United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom) and Japan.

The Vascular Dementia market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Vascular Dementia market size from 2020 to 2034, segmented by seven major markets. The Vascular Dementia market report also covers current Vascular Dementia treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Vascular Dementia market.

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Key Takeaways from the Vascular Dementia Market Report
• The Vascular Dementia market size was valued approximately USD 2,399 million in 2023 and is anticipated to grow with a significant CAGR during the study period (2020-2034)
• In March 2025, Hemostemix Inc. ('Hemostemix' or 'HEM') (TSXV: HEM) (OTCQB: HMTXF) (FSE: 2VF0), a company specializing in autologous angiogenic stem cell therapies, showcased its ACP-01 treatment for vascular dementia to Wall Street. Having already treated 498 patients for various cardiovascular conditions, the company highlighted ACP-01's unique ability to stimulate angiogenesis, increase neurotrophic factor expression in the brain, and activate specific chemokines. "These mechanisms strongly indicate ACP-01's potential as an effective therapy for vascular dementia," said Dr. Fraser Henderson, Neurosurgeon and Chief Medical Officer of Hemostemix Inc.
• In September 2024, Vesper Bio has shared results from a Phase I trial of VES001, a potential disease-modifying therapy for frontotemporal dementia (FTD) aimed specifically at patients with progranulin gene mutations (GRN). The company administered the first dose to a participant in the trial last December. The study, which included 78 healthy volunteers, was conducted to evaluate the safety, tolerability, pharmacokinetics, and pharmacodynamic target engagement of VES001.
• The market size across the 7MM is projected to grow at a CAGR of 4%, driven by heightened disease awareness, improved diagnostics, and the introduction of new therapies.
• Among European countries, Germany reported the largest market size for Vascular Dementia at approximately USD 136 million in 2023, while Spain had the smallest market size at around USD 74 million.
• The estimated market size for Vascular Dementia in Japan was approximately USD 480 million in 2023, representing 20% of the total market across the 7MM.
• In 2023, the total number of prevalent dementia cases in the 7MM was approximately 22 million.
• In 2023, the total number of diagnosed prevalent cases of vascular dementia in the United States was approximately 1 million.
• In 2023, the United States had the highest diagnosed prevalent population of vascular dementia, making up about 40% of the total in the 7MM. In comparison, the EU4 and the UK represented approximately 32%, while Japan accounted for around 28% of the overall population share.
• In 2023, Germany had the highest number of prevalent dementia cases among the EU4 countries, with 1,843 thousand cases, followed by Italy with 1,365 thousand cases. Conversely, Spain reported the lowest number of cases, totaling 934 thousand.
• In 2023, it was estimated that Japan had approximately 320 thousand diagnosed prevalent cases of vascular dementia, primarily in the 81-90 years age group.
• DelveInsight estimates indicate that there were about 3 million diagnosed prevalent cases of dementia in Japan in 2023.
• Key Vascular Dementia Companies: Charsire Biotechnology Corp, ProNeurogen Therapeutics, Resverlogix, Cyclerion Therapeutics, CSPC-NBP Pharma, Johnson & Johnson, Materia Medica Holding, Eisai Co., Ltd., Shineway Pharma, Merz Pharma, Ever Neuro Pharma GmbH, Zhejiang Otsuka Pharma, Janssen, LP, GE Healthcare, and others
• Key Vascular Dementia Therapies: BAC, PNA1, Apabetalone, CY6463, Butylphthalide soft capsule, galantamine, Prospecta, donepezil hydrochloride (Aricept), SaiLuoTong capsule, Akatinol Memantine, Cerebrolysin, Cilostazol, risperidone, DatSCAN, and others
• The Vascular Dementia epidemiology based on age-specific cases analyzed that Vascular Dementia (VaD) is highly prevalent in age group of 60 years and above, while below this age group the disease appears to be rare
• The Vascular Dementia market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Vascular Dementia pipeline products will significantly revolutionize the Vascular Dementia market dynamics.

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Vascular Dementia Overview
Vascular dementia is a common form of dementia caused by impaired blood flow to the brain, leading to cognitive decline. It occurs due to conditions that damage blood vessels, such as strokes, small vessel disease, or a series of mini-strokes (transient ischemic attacks). These events prevent adequate oxygen and nutrients from reaching brain tissue, resulting in damage that affects memory, reasoning, and other cognitive functions.
Symptoms of vascular dementia vary based on the brain regions affected but commonly include confusion, difficulty with attention and problem-solving, slowed thinking, and mood changes such as depression or apathy. In some cases, physical symptoms like weakness or trouble walking may also appear.
Risk factors include hypertension, diabetes, high cholesterol, smoking, and a history of cardiovascular disease. Early detection and management of these risk factors can help prevent or delay its onset. Diagnosis typically involves cognitive assessments, imaging techniques like MRI or CT scans, and evaluation of medical history.
While there is no cure for vascular dementia, treatment focuses on managing underlying conditions and improving symptoms. Lifestyle changes, medications for controlling blood pressure or cholesterol, and cognitive therapies are integral parts of care. Early intervention and support can enhance quality of life for those affected.

Vascular Dementia Epidemiology Segmentation in the 7MM
• total prevalent cases
• diagnosed prevalent cases
• age-specific diagnosed prevalent cases

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Vascular Dementia Emerging Drugs
• BAC: Charsire Biotechnology Corp
BAC (also called CSTC1, CHARSIRE Trauma Complex 1), a component of soybean extraction developed by Charsire Biotechnology Corp, is under investigation to treat a variety of diseases, including AD and Vascular Dementia. BAC is a vapor fraction from seeds of Glycine max (L.) Merr. BAC in its studies showed to promote the proliferation of neuroblastoma IMR-32 cells, and this observation may correlate to the improvement of the cognitive performance in the heavy metal-induced AD mice and the Vascular Dementia-resembled rats when treated with BAC.
• PNA1: ProNeurogen Therapeutics
PNA1, a rationally-designed Angiotensin-(1-7) Mas receptor agonists that have enhanced BBB penetration half-life and designed to inhibit chronic inflammatory pathways in both the brain and the cerebrovasculature endothelium. These pathways are involved in vascular dementia and neuropathic pain. These novel peptide formulations are designed to act on Mas receptors (MasR) within the brain vascular endothelium and neuronal cells and microglia to decrease brain ROS production and neuroinflammation. The drug candidate is based on technology developed at the University of Arizona.

Vascular Dementia Market Outlook
Vascular dementia is a common condition with no effective approved pharmacological treatments available. Vascular dementia arises from ischemic insults such as hemorrhage and hypoperfusion that trigger neurodegeneration by depriving nerve cells of oxygen and glucose. Vascular Dementia has multifactorial etiopathology, diverse clinical manifestations, and multiple clinical subtypes. Moreover, the diagnostic criteria are not consistent worldwide.

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Scope of the Vascular Dementia Market Report
• Coverage- 7MM
• Vascular Dementia Companies- Eisai Inc., Ever Neuro Pharma GmbH, Geny Research Corp, Novartis, Charsire Biotechnology Corp, Merz Pharmaceuticals GmbH, LLC Merz Pharma, Otsuka Pharmaceutical Co., Ltd, Johnson & Johnson Pharmaceutical Research & Development LLC, and others.
• Vascular Dementia Therapies- Butylphthalide soft capsule, Cerebrolysin, 0.9 % NaCl, and others.
• Vascular Dementia Market Dynamics: Vascular Dementia Market drivers and Vascular Dementia Market Barriers
• Vascular Dementia Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Vascular Dementia Unmet Needs, KOL's views, Analyst's views, Vascular Dementia Market Access and Reimbursement

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Table of Content
1. Key Insights
2. Report Introduction
3. Vascular Dementia Market Overview at a Glance
4. Vascular Dementia Market: Future Perspective
5. Executive Summary of Vascular Dementia
6. Key Events
7. Disease Background and Overview
8. Vascular Dementia Epidemiology and Patient Population
9. Vascular Dementia Patient Journey
10. Emerging Vascular Dementia Drugs
11. Vascular Dementia: Seven Major Market Analysis
12. Vascular Dementia KOL Views
13. Vascular Dementia Market Drivers
14. Vascular Dementia Market Barriers
15. Vascular Dementia SWOT Analysis
16. Vascular Dementia Unmet Needs
17. Reimbursement and Market Access
18. Appendix
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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