Gaucher Disease Market on Track for Major Expansion by 2032, According to DelveInsight | Sanofi, Avro Bio, Freeline Therapeutics, Takeda, Pfizer, Genzyme, Actelion, Prevail Therapeutics

DelveInsight's "Gaucher Disease Market Insights, Epidemiology, and Market Forecast-2032′′ report offers an in-depth understanding of the Gaucher Disease, historical and forecasted epidemiology as well as the Gaucher Disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

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Some of the key facts of the Gaucher Disease Market Report:
• The Gaucher Disease market size is anticipated to grow with a significant CAGR during the study period (2019-2032)
• In May 2025, Treatment with the investigational gene therapy FLT201 provided lasting clinical benefits for up to 21 months in individuals with Gaucher disease type 1, according to new clinical trial results. Spur Therapeutics, the developer of FLT201, shared these findings at the 28th Annual Meeting of the American Society of Gene and Cell Therapy (ASGCT) in New Orleans.
• In April 2024, With funding support from Sanofi, a real-world study found that treatment with Cerdelga (eliglustat) - a substrate reduction therapy approved in the U.S. for adults with type 1 Gaucher disease - was safe and showed therapeutic promise in pediatric patients. The researchers noted, "This case series offers real-world insights on [Cerdelga] use in children with [Gaucher type 1], shedding light on its potential to enhance clinical outcomes and improve disease management."
• As per Zimran et al. (2022), GD type-specific prevalence estimates per 100,000 population were GD1: 0.26-0.63; GD2 and GD3: 0.02- 0.08 (Europe only); estimates for GD type unspecified or overall ranged 0.11- 139.0/100,000 inhabitants, highest for North America
• According to a study by Oto et al. (2021), the prevalence associated with GD in Japan is lower than that in Western countries (1 per 330,000 vs. 1.16 per 100,000 live births, respectively). In Japan, only ~150 patients were estimated to have GD and the proportion of GD type 1 is rarer than that in other countries
• According to Hughes & Sidransky (2023), type 1 GD (GD1) is the most prevalent type in the United States, Europe, and occurs with greater frequency in the Ashkenazi Jewish population. Type 2 GD (GD2) occurs in all ethnic types
• According to a recent nationwide survey by Sawada et al.(2022), in Japan, the prevalence of GD is estimated to be 1in 530,000, and more than 50% of these patients have GD2 or GD3
• Key Gaucher Disease Companies: Sanofi, Avro Bio, Freeline Therapeutics, Takeda, Pfizer, Genzyme, Actelion, Prevail Therapeutics, Eli Lilly and Company, Amicus Therapeutics, Protalix, ISU Abxis Co., Ltd., and others
• Key Gaucher Disease Therapies: Venglustat, AVR-RD-02, FLT201, velaglucerase alfa, Taliglucerase alfa, Cerezyme®, Imiglucerase, Eliglustat tartrate, ISU302, Miglustat, Methylprednisolone, Sirolimus, afegostat tartrate, PRX-112, and others
• The Gaucher Disease epidemiology based on gender analyzed that females born with GD does not have any family history whereas male child born with GD have family history
• The Gaucher Disease market is expected to surge due to the disease's increasing prevalence and awareness during the forecast period. Furthermore, launching various multiple-stage Gaucher Disease pipeline products will significantly revolutionize the Gaucher Disease market dynamics.

Gaucher Disease Overview
Gaucher Disease is a rare genetic disorder that falls under the category of lysosomal storage diseases. It is caused by mutations in the GBA gene, which encodes an enzyme called glucocerebrosidase. This enzyme is crucial for breaking down a fatty substance called glucocerebroside within lysosomes, the cellular organelles responsible for waste disposal.
When glucocerebroside is not broken down properly, it accumulates in cells, particularly in the liver, spleen, and bone marrow. This accumulation leads to the various symptoms associated with the disease.

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Gaucher Disease Epidemiology
The epidemiology section provides insights into the historical, current, and forecasted epidemiology trends in the seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides a detailed analysis of the diagnosed patient pool and future trends.

Gaucher Disease Epidemiology Segmentation:
The Gaucher Disease market report proffers epidemiological analysis for the study period 2019-2032 in the 7MM segmented into:
• Total Prevalence of Gaucher Disease
• Prevalent Cases of Gaucher Disease by severity
• Gender-specific Prevalence of Gaucher Disease
• Diagnosed Cases of Episodic and Chronic Gaucher Disease

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Gaucher Disease Drugs Uptake and Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the Gaucher Disease market or expected to get launched during the study period. The analysis covers Gaucher Disease market uptake by drugs, patient uptake by therapies, and sales of each drug.
Moreover, the therapeutics assessment section helps understand the drugs with the most rapid uptake and the reasons behind the maximal use of the drugs. Additionally, it compares the drugs based on market share.
The report also covers the Gaucher Disease Pipeline Development Activities. It provides valuable insights about different therapeutic candidates in various stages and the key companies involved in developing targeted therapeutics. It also analyzes recent developments such as collaborations, acquisitions, mergers, licensing patent details, and other information for emerging therapies.

Gaucher Disease Therapies and Key Companies
• Venglustat: Sanofi
• AVR-RD-02: Avro Bio
• FLT201: Freeline Therapeutics

Discover more about therapies set to grab major Gaucher Disease market share @ Gaucher Disease Treatment Market
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Gaucher Disease Market Strengths
• Increasing awareness of Gaucher disease
• Advances in the understanding of Gaucher disease pathogenesis
• Pipeline consists of late and early stage candidates.

Gaucher Disease Market Opportunities
• Uptake of potential emerging therapies with better clinical profile expected to be medium-fast due to the present unmet needs
• Several organizations are actively working to provide information and increase awareness of such disorders

Scope of the Gaucher Disease Market Report
• Study Period: 2019-2032
• Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
• Key Gaucher Disease Companies: Sanofi, Avro Bio, Freeline Therapeutics, Takeda, Pfizer, Genzyme, Actelion, Prevail Therapeutics, Eli Lilly and Company, Amicus Therapeutics, Protalix, ISU Abxis Co., Ltd., and others
• Key Gaucher Disease Therapies: Venglustat, AVR-RD-02, FLT201, velaglucerase alfa, Taliglucerase alfa, Cerezyme®, Imiglucerase, Eliglustat tartrate, ISU302, Miglustat, Methylprednisolone, Sirolimus, afegostat tartrate, PRX-112, and others
• Gaucher Disease Therapeutic Assessment: Gaucher Disease current marketed and Gaucher Disease emerging therapies
• Gaucher Disease Market Dynamics: Gaucher Disease market drivers and Gaucher Disease market barriers
• Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
• Gaucher Disease Unmet Needs, KOL's views, Analyst's views, Gaucher Disease Market Access and Reimbursement

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Table of Contents
1. Gaucher Disease Market Report Introduction
2. Executive Summary for Gaucher Disease
3. SWOT analysis of Gaucher Disease
4. Gaucher Disease Patient Share (%) Overview at a Glance
5. Gaucher Disease Market Overview at a Glance
6. Gaucher Disease Disease Background and Overview
7. Gaucher Disease Epidemiology and Patient Population
8. Country-Specific Patient Population of Gaucher Disease
9. Gaucher Disease Current Treatment and Medical Practices
10. Gaucher Disease Unmet Needs
11. Gaucher Disease Emerging Therapies
12. Gaucher Disease Market Outlook
13. Country-Wise Gaucher Disease Market Analysis (2019-2032)
14. Gaucher Disease Market Access and Reimbursement of Therapies
15. Gaucher Disease Market Drivers
16. Gaucher Disease Market Barriers
17. Gaucher Disease Appendix
18. Gaucher Disease Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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About DelveInsight
DelveInsight is a leading Healthcare Business Consultant, and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.
It also offers Healthcare Consulting Services, which benefits in market analysis to accelerate the business growth and overcome challenges with a practical approach.

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