Single Ventricle Heart Disease Market: Epidemiology, Therapies, Companies, DelveInsight | Mezzion, Gene Techno Science, Longerevon

Single Ventricle Heart Disease emerging therapies, such as Udenafil, JRM-001, and others, are expected to boost the Single Ventricle Heart Disease Market in the upcoming years.

DelveInsight has launched a new report on "Single Ventricle Heart Disease - Market Insights, Epidemiology, and Market Forecast-2034" that delivers an in-depth understanding of the Single Ventricle Heart Disease, historical and forecasted epidemiology as well as the Single Ventricle Heart Disease market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan.

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Some of the key facts of the Single Ventricle Heart Disease Market Report:

The Single Ventricle Heart Disease (SVHD) treatment market is expected to maintain a steady Compound Annual Growth Rate (CAGR) throughout the forecast period from 2024 to 2034. This projected growth is largely fueled by improvements in diagnostic technologies, heightened awareness of the disease, and a growing number of diagnosed cases.
The expansion of the SVHD market is influenced by several contributing factors, such as genetic abnormalities and other congenital heart defects. Despite the significant burden posed by SVHD, comprehensive data on long-term patient outcomes and the economic implications remain limited, and an all-encompassing reference covering the full scope of the condition is currently unavailable.
Looking ahead, the SVHD market is likely to be propelled by the development activities of companies like Mezzion Pharma and Metcela, which have assets in mid-to-late-stage development. The expected approvals of therapies such as Udenafil and JRM-001 within the forecast timeframe are anticipated to significantly boost market growth.
Additionally, emerging research continues to highlight the therapeutic promise of stem cell treatments for pediatric patients with congenital heart disease, particularly those with single ventricle physiology. Preclinical trials have shown that various types of stem cells offer measurable benefits in relevant animal models, with the secretome-molecules secreted by stem cells-identified as a key therapeutic component.
Analysis of single ventricle heart disease reveals that these defects are rare, occurring in approximately 5 out of every 100,000 newborns. Despite their rarity, they represent some of the most complex congenital heart conditions and typically necessitate at least one surgical intervention.
Further findings indicated that the most frequently observed adult congenital heart diseases (ACHDs) include **atrial septal defect (20.5%)**, **ventricular septal defect (20.5%)**, **tetralogy of Fallot (12.9%)**, and **univentricular heart (UVH)/single ventricle (SV) defects (6.6%)**.
In August 2024, the American Heart Association, in collaboration with Additional Ventures, launched a $13 million research initiative to explore the biological mechanisms underlying SVHD. This program funds five research teams across institutions like Stanford University and Nationwide Children's Hospital, focusing on improving clinical care and understanding of SVHD .
Key Single Ventricle Heart Disease companies such as Mezzion, Gene Techno Science, Longerevon, and others are evaluating new drugs for Single Ventricle Heart Disease to improve the treatment landscape.
Promising Single Ventricle Heart Disease therapies include Udenafil, JRM-001, and others.

Single Ventricle Heart Disease Overview

According to Boston Children's Hospital, single ventricle defects are congenital heart conditions in which one of the heart's ventricles is underdeveloped or unable to function properly. In some cases, a heart valve may also be missing. Several forms of this condition exist, including **tricuspid atresia, hypoplastic left heart syndrome (HLHS), double inlet left ventricle (DILV), double outlet right ventricle (DORV), pulmonary atresia with intact ventricular septum (PA/IVS),** and others.

The precise cause of single ventricle heart disease is still unclear. These defects arise from complex developmental processes and typically occur sporadically, though they are occasionally associated with conditions like **situs inversus** or **heterotaxy**. Rare familial cases have been reported, but no definitive genetic cause has been identified.

Children with this condition often experience **cyanosis**-a bluish tint to the skin-due to the mixing of oxygen-rich and oxygen-poor blood in the heart. The degree of cyanosis and the urgency of treatment depend on the type and severity of the defect. Some children may require early intervention to ensure adequate oxygen supply to the body.

Single Ventricle Heart Disease Market Outlook

The single ventricle heart disease therapeutics market is projected to grow further, driven by an increasing number of cases, technological progress, and the introduction of new therapies during the forecast period (2024-2034).

In May 2021, the U.S. FDA accepted a New Drug Application (NDA) for **Udenafil**, intended to treat patients aged 12 and older with single ventricle heart disease who have undergone **Fontan palliation**.

Ongoing research and persistent efforts continue to bring optimism for improved treatment options and the potential for a cure. As per DelveInsight, the single ventricle heart disease market across the **7 major markets (7MM)** is expected to undergo substantial changes between 2020 and 2034.

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Single Ventricle Heart Disease Emerging Drugs
Dazukibart (PF-06823859): Pfizer

Scope of the Single Ventricle Heart Disease Market Report
Study Period: 2020-2034
Coverage: 7MM [The United States, EU5 (Germany, France, Italy, Spain, and the United Kingdom), and Japan]
Key Single Ventricle Heart Disease Companies: Mezzion, Gene Techno Science, Longerevon, and others
Key Single Ventricle Heart Disease Therapies: Udenafil, JRM-001, and others
Single Ventricle Heart Disease Therapeutic Assessment: Single Ventricle Heart Disease current marketed and Single Ventricle Heart Disease emerging therapies
Single Ventricle Heart Disease Market Dynamics: Single Ventricle Heart Disease market drivers and Single Ventricle Heart Disease market barriers
Competitive Intelligence Analysis: SWOT analysis, PESTLE analysis, Porter's five forces, BCG Matrix, Market entry strategies
Single Ventricle Heart Disease Unmet Needs, KOL's views, Analyst's views, Single Ventricle Heart Disease Market Access and Reimbursement

To know what's more in our Single Ventricle Heart Disease report, visit https://www.delveinsight.com/report-store/single-ventricle-heart-disease-market?utm_source=openpr&utm_medium=pressrelease&utm_campaign=kpr

Key benefits of the Single Ventricle Heart Disease Market Report:
Single Ventricle Heart Disease market report covers a descriptive overview and comprehensive insight of the Single Ventricle Heart Disease Epidemiology and Single Ventricle Heart Disease market in the 7MM (the United States, EU5 (Germany, Spain, France, Italy, UK) & Japan).
The Single Ventricle Heart Disease market report provides insights into the current and emerging therapies.
The Single Ventricle Heart Disease market report provides a global historical and forecasted market covering drug outreach in 7MM.
The Single Ventricle Heart Disease market report offers an edge that will help in developing business strategies by understanding trends shaping and driving the Single Ventricle Heart Disease market.

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Table of Contents

1. Report Introduction
2. Executive Summary
3. SWOT analysis
4. Single Ventricle Heart Disease Patient Share (%) Overview at a Glance
5. Single Ventricle Heart Disease Market Overview at a Glance
6. Single Ventricle Heart Disease Disease Background and Overview
7. Single Ventricle Heart Disease Epidemiology and Patient Population
8. Country-Specific Patient Population of Single Ventricle Heart Disease
9. Single Ventricle Heart Disease Current Treatment and Medical Practices
10. Unmet Needs
11. Single Ventricle Heart Disease Emerging Therapies
12. Single Ventricle Heart Disease Market Outlook
13. Country-Wise Single Ventricle Heart Disease Market Analysis (2020-2034)
14. Market Access and Reimbursement of Therapies
15. Market drivers
16. Market barriers
17. Appendix
18. Single Ventricle Heart Disease Report Methodology
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

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Related Reports:

Single Ventricle Heart Disease Pipeline Insights, DelveInsight

"Single Ventricle Heart Disease Pipeline Insight, 2024" report by DelveInsight outlines comprehensive insights of present clinical development scenarios and growth prospects across the Single Ventricle Heart Disease market. A detailed picture of the Single Ventricle Heart Disease pipeline landscape is provided, which includes the disease overview and Single Ventricle Heart Disease treatment guidelines.

Contact Info:

Kritika Rehani, Assistant Manager, Marketing & Branding
krehani@delveinsight.com
info@delveinsight.com
www.delveinsight.com
+14699457679

About DelveInsight

DelveInsight is a leading Business Consultant and Market Research firm focused exclusively on life sciences. It supports Pharma companies by providing comprehensive end-to-end solutions to improve their performance.

This release was published on openPR.