Press release
mRNA Synthesis and Manufacturing Services Market Dynamics Including Key Drivers Challenges and Investment Opportunities to 2034
mRNA Synthesis and Manufacturing Services Market
According to company's newest research, the Global mRNA Synthesis and Manufacturing Services Market is worth USD 859.4 Million in 2024 and is predicted to reach USD 936.6 Million by the year 2034, with a promising CAGR of 1.1% between 2025 and 2034.
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Messenger RNA (mRNA) molecules are single-stranded nucleic acids transcribed from DNA, playing a critical role in gene expression by guiding the synthesis of encoded proteins within cells. Due to their inherent adaptability and versatility, mRNA platforms have emerged as a promising foundation for the development of therapeutic and prophylactic vaccines targeting a wide spectrum of infectious and chronic diseases. Compared to conventional pharmaceuticals, mRNA vaccines demonstrate higher success rates, enhanced immunogenicity, and cost-effective production processes. Notably, the initial COVID-19 vaccines authorized for global use were mRNA-based, with approvals extended for additional viral pathogens, thereby driving a significant surge in demand for mRNA manufacturing capacity.
The therapeutic potential of mRNA extends beyond vaccines, with promising applications in treating complex conditions including infectious diseases, metabolic genetic disorders, cancer, cardiovascular, and cerebrovascular diseases. Importantly, mRNA therapies carry no risk of inadvertent infection or insertional mutagenesis, offering an advantage over traditional gene therapies. Furthermore, mRNA enables sustained protein expression through continuous translation, yielding superior therapeutic efficacy relative to conventional protein or peptide drugs.
The expansion of the mRNA synthesis and manufacturing services market is primarily fueled by the increasing prevalence of rare diseases such as propionic acidemia, methylmalonic acidemia, glycogen storage diseases as well as metabolic and immunological disorders. Additionally, the rising incidence of chronic conditions, including cancer, cardiovascular diseases, pulmonary ailments, and chronic kidney disease, further drives demand. Recent advancements in biopharmaceutical technologies have prompted service providers to scale up production capacities and infrastructure to meet the growing requirements of this innovative biologic class.
Market growth is further supported by the increasing number of clinical trials targeting cancer and infectious diseases. Current industry trends feature heightened investments by key players, strategic mergers and partnerships, and amplified research and development activities. For example, in April 2021, American mRNA therapeutics company Arcturus Therapeutics established a joint venture with Axcelead, Inc. in Japan, forming a new entity in Chiba Prefecture and initiating the construction of a manufacturing facility in Minamisoma City, Fukushima Prefecture. Such strategic investments are expected to significantly contribute to the sector's growth trajectory in the coming years.
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The expansion of mRNA synthesis and manufacturing services is, however, being hampered by a dearth of manufacturing procedures that are flexible, sustainable, and efficient in terms of cost. Also, the lengthy process of approvals and long-term clinical trials will hamper the market growth in the forecasting period.
The mRNA synthesis and manufacturing services market in North America will be driven by the availability of significant financing for research, the expansion of federal programmes toward RNA-based therapeutics, and the increasing number of clinical studies.
Some of the significant market players in the mRNA synthesis and manufacturing services market are eTheRNA (Etherna Immunotherapies), Eurogentec, Aldevron, biosynthesis, Biomay, Jena Biosciences, APExBIO, TriLink BioTechnologies, CELLSCRIPT, Thermo Fisher Scientific, New England Biolabs, BioNTech (Pfizer), Translate Bio, CureVac, Moderna, Ethris (AstraZeneca), Kernal Biologics, Silence Therapeutics, In-Cell-Art, Anima Biotch, H3 Biomedicine Inc., Tiba Biotechnology, Arcturus Therapeutics, Ionis Pharmaceuticals, Inc., Stemirna Therapeutics Co., Ltd., eFFECTOR Therapeutics, Inc., Ziphius Therapeutics NV, miRagen Therapeutics, Inc., RNAimmune (Sirnaomics), Skyhawk Therapeutics, Inc, Strand Therapeutics Inc., and other Prominent Players.
Key Developments in the Market :
• In Aug 2022, A novel enzymatic mRNA capping solution for the manufacture of mRNA was introduced by New England Biolabs® under the name Faustovirus Capping Enzyme. This new enzyme boosts the capping effectiveness and scalability for mRNA manufacturing workflows, including vaccine production.
• In Jan 2022, Pfizer and BioNTech signed a new global collaboration agreement to work together on developing the first mRNA-based shingles vaccine. Both Pfizer's antigen technology and BioNTech's proprietary mRNA technology will be utilised to develop potential product candidates. It is expected that clinical trials will begin in the second half of the year 2022.
• In Oct 2021, Silence Therapeutics and Hansoh Pharma announced a collaboration to develop therapeutics utilising Silence's mRNAi GOLDTM Platform. The upfront cash payment from Hansoh is expected to be sixteen million dollars, and the possible milestone payments for Silence might be as high as one billion three hundred million dollars.
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Market Segmentation:
Global mRNA Synthesis and Manufacturing Services Market, by Type of Industry 2022-2030 (Value US$ Mn)
• Therapeutics and Vaccine Developers
• CDMO Organizations
• Custom Synthesis/Other Service Providers
Global mRNA Synthesis and Manufacturing Services Market, by Applications, 2022-2030 (Value US$ Mn)
• Infectious Disease Vaccines
• Other Vaccines
• Therapeutics and Others
Global mRNA Synthesis and Manufacturing Services Market, by Scale of Operation, 2022-2030 (Value US$ Mn)
• Research / Preclinical
• Clinical
• Commercial
Global mRNA Synthesis and Manufacturing Services Market, by Region, 2022-2030 (Value US$ Mn)
• North America
• Europe
• Asia Pacific
• Latin America
• Middle East & Africa
North America mRNA Synthesis and Manufacturing Services Market, by Country, 2022-2030 (Value US$ Mn)
• U.S.
• Canada
Europe mRNA Synthesis and Manufacturing Services Market, by Country, 2022-2030 (Value US$ Mn)
• Germany
• France
• Italy
• Spain
• Russia
• Rest of Europe
Asia Pacific mRNA Synthesis and Manufacturing Services Market, by Country, 2022-2030 (Value US$ Mn)
• India
• China
• Japan
• South Korea
• Australia & New Zealand
Latin America mRNA Synthesis and Manufacturing Services Market, by Country, 2022-2030 (Value US$ Mn)
• Brazil
• Mexico
• Rest of Latin America
Middle East & Africa mRNA Synthesis and Manufacturing Services Market, by Country, 2022-2030 (Value US$ Mn)
• GCC Countries
• South Africa
• Rest of Middle East & Africa
Why should buy this report:
To receive a comprehensive analysis of the prospects for the global mRNA Synthesis and Manufacturing Services Market
To receive an industry overview and future trends of the mRNA Synthesis and Manufacturing Services Market
To analyze mRNA Synthesis and Manufacturing Services Market drivers and challenges
To get information on the mRNA Synthesis and Manufacturing Services Market size (Value US$ Mn) forecast to 2030
Significant investments, mergers & acquisitions in the mRNA Synthesis and Manufacturing Services Market industry
Read Overview Report- https://www.insightaceanalytic.com/report/global-mrna-synthesis-and-manufacturing-services-market/1185
About Us:
InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.
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