Postoperative Pain Drugs Market 2034: EMA, PDMA, FDA Approvals, Medication, Prevalence, NICE Approval, Therapies, Clinical Trials and Companies by DelveInsight

(Albany, USA) DelveInsight's "Postoperative Pain Market Insights, Epidemiology, and Market Forecast-2034" report delivers an in-depth understanding of Postoperative Pain, historical and forecasted epidemiology as well as the Postoperative Pain market trends in the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom), and Japan.

The Postoperative Pain market report provides current treatment practices, emerging drugs, the market share of the individual therapies, and the current and forecasted Postoperative Pain market size from 2020 to 2034, segmented by seven major markets. The Report also covers current Postoperative Pain treatment practice/algorithm, market drivers, market barriers, and unmet medical needs to curate the best opportunities and assesses the underlying potential of the Postoperative Pain market.

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Some facts of the Postoperative Pain Market Report are:
• The Postoperative Acute Pain market size in US was found to be ~USD 1,800 million in 2023, which is further expected to increase by 2034.
• Leading Postoperative Pain companies working in the market are Taiwan Liposome Company (TLC), Teikoku Pharma, Concentric Analgesics, Arthritis Innovation Corporation, MedinCell, Surface Ophthalmics, Salvat Laboratories, Vertex Pharmaceuticals, Formosa Pharmaceuticals, Avenue Therapeutics, Cali Pharmaceuticals LLC, and others.
• Key Postoperative Pain Therapies expected to launch in the market are TLC590, TPU-006 (Dexmedetomidine Transdermal System [DMTS]), Libvatrep (SAF312), Vocacapsaicin (CA-008), Nepafenac PPDS/Nepafenac Evolute, F14 (sustained-release celecoxib)/mdc-CWM (Celecoxib), SURF-201 (betamethasone 0.2% in KLARITY vehicle), SVT-15473 (clobetasol propionate ophthalmic nanoemulsion 0.05%), QUTENZA (8% capsaicin), VX-548, APP13007 (clobetasol propionate ophthalmic nanosuspension), OCS-01 (dexamethasone cyclodextrin nanoparticle ophthalmic suspension 1.5%), NTM-001, CL-108 (hydrocodone/acetaminophen/promethazine or HYDEXOR), and others.
• In February 2025, Food and Drug Administration (FDA) recently approved a new, non-opioid prescription pill-suzetrigine. Sold under the brand name JournavxTM, the drug is helpful in treating moderate-to-severe acute (short-term) pain in adults.
• In January 2025, Scilex Holding Company (Nasdaq: SCLX, "Scilex" or "Company"), an innovative revenue-generating company focused on acquiring, developing and commercializing non-opioid pain management products for the treatment of acute and chronic pain and, following the formation of its proposed joint venture with IPMC Company, in neurodegenerative and cardiometabolic disease, today announced that it will be filing today of a Supplemental New Drug Application (SNDA) with the FDA for ELYXYB® in acute pain indication.
• In January 2025, U.S. Food and Drug Administration approved Journavx (suzetrigine) 50 milligram oral tablets, a first-in-class non-opioid analgesic, to treat moderate to severe acute pain in adults. Journavx reduces pain by targeting a pain-signaling pathway involving sodium channels in the peripheral nervous system, before pain signals reach the brain.
• In August, 2024: Mylan Specialty, LP announced that MR-107A-02 is being studied to investigate its efficacy and safety for treatment of acute pain after herniorrhaphy.
• In August, 2024: Jiangsu HengRui Medicine Co., Ltd. announced that a study is being conducted to evaluate the safety and efficacy of bupivacaine liposome injection for local infiltration analgesia in pediatric orthopedic surgery in the real world.
• In June, 2024: Johnson & Johnson Consumer Inc. announced that the purpose of their study is to evaluate effectiveness of a fixed combination of acetaminophen/naproxen sodium compared with placebo for reduction of pain when administered as multiple doses over a 48-hour period.
• In March 2024, Formosa Pharmaceuticals and AimMax Therapeutics announced FDA approval for clobetasol propionate ophthalmic suspension 0.05% (APP13007), to treat post-operative inflammation and pain after ocular surgery.

Postoperative Pain Overview
Postoperative pain is a common and significant clinical issue experienced by patients following surgical procedures. Postoperative pain management is crucial for enhancing patient recovery, reducing hospital stays, and preventing complications such as chronic pain. Postoperative pain varies depending on the type of surgery, individual patient factors, and the effectiveness of pain control strategies. Postoperative pain can range from mild discomfort to severe, debilitating pain that affects mobility and overall well-being.

Postoperative pain treatment typically involves multimodal analgesia, combining medications like opioids, nonsteroidal anti-inflammatory drugs (NSAIDs), and regional anesthesia techniques. Postoperative pain relief through personalized approaches is increasingly prioritized to balance effective pain control and minimize opioid-related side effects. Postoperative pain monitoring plays a key role in assessing the effectiveness of interventions and adjusting treatment plans accordingly.

Postoperative pain research continues to explore novel therapeutic options, including non-pharmacological methods such as physical therapy and cognitive behavioral therapy. Postoperative pain in minimally invasive surgeries is generally less intense, but still requires adequate attention. Postoperative pain guidelines provided by healthcare authorities help standardize care and improve outcomes. Postoperative pain awareness and education empower patients to communicate their pain levels effectively. Postoperative pain control remains a central focus in enhancing the quality of surgical care and patient satisfaction.

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Postoperative Pain Market
The Postoperative Pain market outlook of the report helps to build a detailed comprehension of the historical, current, and forecasted Postoperative Pain market trends by analyzing the impact of current Postoperative Pain therapies on the market and unmet needs, and drivers, barriers, and demand for better technology.

This segment gives a thorough detail of the Postoperative Pain market trend of each marketed drug and late-stage pipeline therapy by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action, compliance rate, growing need of the market, increasing patient pool, covered patient segment, expected launch year, competition with other therapies, brand value, their impact on the market and view of the key opinion leaders. The calculated Postoperative Pain market data are presented with relevant tables and graphs to give a clear view of the market at first sight.

The Postoperative Pain market is driven by the increasing number of surgical procedures worldwide, including orthopedic, cardiovascular, and cosmetic surgeries, which directly correlate with a higher demand for effective pain management solutions. Growing awareness about the importance of adequate pain control in improving patient recovery outcomes, alongside advancements in multimodal analgesia and non-opioid pain therapies, further supports market growth. Additionally, the development of long-acting local anesthetics, nerve block techniques, and patient-controlled analgesia systems is contributing to innovation within the Postoperative Pain market.

However, the market faces several barriers. The opioid crisis has led to stricter regulations and a decline in opioid prescriptions, pushing the need for safer alternatives, which are often costlier or still in development. Variability in pain perception among patients, lack of standardized treatment guidelines, and limited access to advanced therapies in low- and middle-income regions also hinder widespread adoption. Furthermore, reimbursement issues and concerns over side effects of certain analgesics pose additional challenges. Despite these hurdles, the Postoperative Pain market continues to evolve, driven by technological innovation, increasing healthcare expenditure, and the urgent need for more personalized and effective pain management strategies.

According to DelveInsight, the Postoperative Pain market in 7MM is expected to witness a major change in the study period 2020-2034.

Postoperative Pain Epidemiology
The Postoperative Pain epidemiology section provides insights into the historical and current Postoperative Pain patient pool and forecasted trends for seven individual major countries. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. This part of the Postoperative Pain market report also provides the diagnosed patient pool, trends, and assumptions.

• The total number of surgical procedures in the US was around 58,190,000 in 2022.
• DelveInsight estimates that there were around 9,765,000, 4,875,000, and 3,458,000 cases of mild, moderate, and severe cases of Postoperative Pain, respectively, in EU4 and the UK in 2022. The cases are projected to increase during the forecast period.

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Postoperative Pain Drugs Uptake
This section focuses on the uptake rate of the potential Postoperative Pain drugs recently launched in the Postoperative Pain market or expected to be launched in 2020-2034. The analysis covers the Postoperative Pain market uptake by drugs, patient uptake by therapies, and sales of each drug.
Postoperative Pain Drugs Uptake helps in understanding the drugs with the most rapid uptake and the reasons behind the maximal use of new drugs and allows the comparison of the drugs based on Postoperative Pain market share and size, which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.

Postoperative Pain Pipeline Development Activities
The Postoperative Pain report provides insights into different therapeutic candidates in Phase II, and Phase III stages. It also analyses Postoperative Pain key players involved in developing targeted therapeutics.

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Postoperative Pain Therapeutics Assessment
Major key companies are working proactively in the Postoperative Pain Therapeutics market to develop novel therapies which will drive the Postoperative Pain treatment markets in the upcoming years are Taiwan Liposome Company (NASDAQ: TLC), Teikoku Pharma, Concentric Analgesics, Arthritis Innovation Corporation, MedinCell (EPA: MEDCL), Surface Ophthalmics, Salvat Laboratories, Vertex Pharmaceuticals (NASDAQ: VRTX), Formosa Pharmaceuticals (TPEx: 6838), Avenue Therapeutics (NASDAQ: ATXI), Cali Pharmaceuticals LLC, and others.

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Postoperative Pain Report Key Insights
1. Postoperative Pain Patient Population
2. Postoperative Pain Market Size and Trends
3. Key Cross Competition in the Postoperative Pain Market
4. Postoperative Pain Market Dynamics (Key Drivers and Barriers)
5. Postoperative Pain Market Opportunities
6. Postoperative Pain Therapeutic Approaches
7. Postoperative Pain Pipeline Analysis
8. Postoperative Pain Current Treatment Practices/Algorithm
9. Impact of Emerging Therapies on the Postoperative Pain Market

Table of Contents
1. Key Insights
2. Executive Summary
3. Postoperative Pain Competitive Intelligence Analysis
4. Postoperative Pain Market Overview at a Glance
5. Postoperative Pain Disease Background and Overview
6. Postoperative Pain Patient Journey
7. Postoperative Pain Epidemiology and Patient Population
8. Postoperative Pain Treatment Algorithm, Current Treatment, and Medical Practices
9. Postoperative Pain Unmet Needs
10. Key Endpoints of Postoperative Pain Treatment
11. Postoperative Pain Marketed Products
12. Postoperative Pain Emerging Therapies
13. Postoperative Pain Seven Major Market Analysis
14. Attribute Analysis
15. Postoperative Pain Market Outlook (7 major markets)
16. Postoperative Pain Access and Reimbursement Overview
17. KOL Views on the Postoperative Pain Market
18. Postoperative Pain Market Drivers
19. Postoperative Pain Market Barriers
20. Appendix
21. DelveInsight Capabilities
22. Disclaimer

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