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Small Interfering RNA (siRNA) Therapeutics Market Revenue Report with Forecast to 2031
According to the latest research by InsightAce Analytic, the Global Small Interfering RNA (siRNA) Therapeutics Market Size is valued at USD 1.6 Bn in 2023 and is predicted to reach USD 4.89 Bn by the year 2031 at a 15.0% CAGR during the forecast period for 2024-2031.
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Small interfering RNA (siRNA) therapeutics represent an advanced gene-silencing technology designed to target specific genes for the treatment of various diseases. The market growth is driven by several key factors, including the increasing number of clinical trials, a relatively short preclinical development timeline, rising government funding for research and development (R&D), and a well-established healthcare infrastructure.
Additionally, the significance of siRNA therapeutics continues to rise, particularly in oncology, as cancer remains one of the leading causes of mortality worldwide. These therapeutics play a pivotal role in regulating gene expression, thereby contributing to market expansion.
List of Prominent Players in the Small Interfering RNA (siRNA) Therapeutics Market:
• GE Healthcare Dharmacon, Inc.
• OPKO Health, Inc.
• Alnylam Pharmaceuticals
• Arrowhead Research Corp
• Sanofi Genzyme
• Genecon Biotechnologies Co., Ltd.
• Arbutus Biopharma Corp
• Silence Therapeutics AG
• Sylentis S.A.
• Olix Pharmaceuticals
• GlaxoSmithKline
• Isis Pharmaceuticals/ Ionis Pharmaceuticals
• BenitecBiopharma Ltd.
• Bio-Path Holdings Inc.
• Calando Pharmaceuticals
Market Dynamics:
Drivers-
The small interfering RNA (siRNA) therapeutics market is expanding due to the increasing demand for precision medicine to address genetic disorders and viral infections. Technological advancements in delivery mechanisms, including nanoparticle- and liposome-based systems, have significantly improved the efficacy and stability of siRNA therapies, enhancing their therapeutic potential. Furthermore, favorable regulatory environments and increased funding for biopharmaceutical research are key factors driving market growth. Strategic collaborations among pharmaceutical companies, academic institutions, and biotech firms are fostering innovation and accelerating the development of targeted therapies.
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Challenges:
The high costs associated with the development and manufacturing of siRNA therapeutics present a significant barrier to market growth. One of the primary technical challenges involves ensuring the efficient delivery and stability of siRNA molecules within the human body, which directly impacts treatment efficacy. Furthermore, the complex regulatory approval processes and extended timelines required for clinical validation contribute to delays in market entry for novel siRNA therapies.
Regional Trends:
North America is expected to maintain a dominant market share in the siRNA therapeutics industry, with robust revenue growth projected in the coming years. This growth is driven by the rising number of clinical trials, new product launches, increased healthcare spending, and substantial government investment in R&D. The region's well-established healthcare infrastructure further supports market expansion.
Meanwhile, the Asia-Pacific (APAC) region is also experiencing significant market growth, fueled by rapid urbanization, advancements in healthcare infrastructure, rising disposable incomes, and supportive regulatory frameworks. Increased awareness about siRNA therapeutics and their potential applications in treating diseases such as cancer and cardiovascular disorders is further contributing to the rapid expansion of the market in this region.
Recent Developments:
• In April 2024, Wave Life Sciences reported ongoing progress in their partnership with GSK and achieved notable breakthroughs in siRNA and RNA editing. Wave partnered with GSK and identified its initial two programs for further development after successfully validating their targets. These applications utilized Wave's advanced GalNAc-siRNA format, which is the next generation in the field of hepatology.
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Segmentation of Small Interfering RNA (siRNA) Therapeutics Market-
By Type-
• Liposome-Based Systemic Therapy
• Nanoparticle-Based Systemic Therapy
• Other
By Application-
• Hospital
• Research Institutions
• Pharmaceutical and Biotechnology Companies
• Academic Institutions
• Other
By Region-
North America-
• The US
• Canada
• Mexico
Europe-
• Germany
• The UK
• France
• Italy
• Spain
• Rest of Europe
Asia-Pacific-
• China
• Japan
• India
• South Korea
• South East Asia
• Rest of Asia Pacific
Latin America-
• Brazil
• Argentina
• Rest of Latin America
Middle East & Africa-
• GCC Countries
• South Africa
• Rest of the Middle East and Africa
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InsightAce Analytic is a market research and consulting firm that enables clients to make strategic decisions. Our qualitative and quantitative market intelligence solutions inform the need for market and competitive intelligence to expand businesses. We help clients gain a competitive advantage by identifying untapped markets, exploring new and competing technologies, segmenting potential markets, and repositioning products. Our expertise is in providing syndicated and custom market intelligence reports with an in-depth analysis with key market insights in a timely and cost-effective manner.https://www.insightaceanalytic.com/images_data/148861653.JPG
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