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Peptide Therapeutics Market Poised for 9.6% CAGR Growth Through 2031, Fueled by Advanced Drug Delivery Technologies | TMR Study

02-26-2025 02:56 AM CET | Health & Medicine

Press release from: Transparency Market Research

Peptide Therapeutics Market

Peptide Therapeutics Market

The global peptide therapeutics market has been experiencing remarkable growth, driven by advancements in drug delivery technologies and an increasing prevalence of chronic diseases. Peptide-based drugs are gaining popularity due to their high specificity, improved safety profiles, and effectiveness in treating conditions such as cancer, metabolic disorders, and autoimmune diseases. Pharmaceutical companies are investing significantly in research and development (R&D) to overcome challenges in peptide drug formulation, particularly in oral peptide delivery. The introduction of innovative technologies such as PEGylation and cyclized peptides is enhancing drug stability and efficacy, fueling further market expansion.

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Market Size and Growth

The peptide therapeutics market was valued at US$ 37.8 billion in 2022 and is projected to grow at a compound annual growth rate (CAGR) of 9.6% from 2023 to 2031. By the end of 2031, the market is expected to surpass US$ 85.9 billion, driven by rising demand for targeted therapies, increased funding for peptide-based drug development, and the growing burden of chronic illnesses worldwide. The rise of innovative peptide-based therapeutic vaccines is another factor contributing to the robust expansion of this market.

Competitive Landscape

The peptide therapeutics industry is characterized by intense competition among key players striving to enhance their market presence through strategic collaborations, product innovations, and mergers & acquisitions. Major companies such as Amgen, Inc., Eli Lilly and Company, Novartis AG, Pfizer, Inc., Sanofi, Takeda Pharmaceutical Company Limited, and Teva Pharmaceutical Industries Ltd. are investing heavily in R&D to develop next-generation peptide drugs. The increasing focus on in-house manufacturing and outsourcing to contract manufacturing organizations (CMOs) also plays a significant role in shaping market dynamics.

Market Segmentation

The peptide therapeutics market is segmented based on various factors, including product type, application, peptide type, and manufacturing type:

• By Product Type: Innovative peptides dominate the market due to high investment in R&D and a strong pipeline of novel peptide drugs.

• By Application: The metabolic segment held the largest market share in 2022, fueled by the rising prevalence of diabetes, obesity, osteoarthritis, and osteoporosis.

• By Peptide Type: Native peptides emerged as the leading category, as they offer improved safety, efficacy, and tolerability compared to synthetic alternatives.

• By Manufacturing Type: The in-house segment led the market in 2022 due to cost-effectiveness, greater control over production processes, and flexibility in drug development.

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Regional Analysis

North America dominated the peptide therapeutics market in 2022, owing to the presence of key pharmaceutical companies and strong investments in drug development. The region's high prevalence of chronic diseases, along with favorable regulatory frameworks, supports market growth.

Asia Pacific is projected to witness significant growth in the coming years due to the rising burden of diabetes and cancer in countries such as China, India, and Japan. The region's expanding healthcare infrastructure and increasing adoption of advanced peptide-based therapies contribute to this upward trend.

Future Outlook

The future of the peptide therapeutics market looks promising, with continuous advancements in drug discovery and development. The growing interest in peptide-based vaccines, coupled with breakthroughs in nanoparticle-formulated peptide solutions and AI-driven drug discovery platforms, is expected to revolutionize the market. Regulatory developments, such as the FDA's 2023 draft guidance on peptide drug products, will play a crucial role in shaping market trends by setting new standards for clinical pharmacology and labeling.

Key Developments

• September 2023: The FDA issued draft guidance on clinical pharmacology and labeling for peptide drug products, focusing on immunogenicity risk assessment and pharmacokinetics.

• June 2023: Asep Medical received a US$ 200,000 grant for developing a nanoparticle-formulated peptide solution to treat chronic sinus infections.

• March 2023: Fujitsu launched its "Biodrug Design Accelerator" platform to support peptide drug discovery research, enhancing the design and testing of peptide drug candidates.

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About Transparency Market Research

Transparency Market Research, a global market research company registered at Wilmington, Delaware, United States, provides custom research and consulting services. Our exclusive blend of quantitative forecasting and trends analysis provides forward-looking insights for thousands of decision makers. Our experienced team of Analysts, Researchers, and Consultants use proprietary data sources and various tools & techniques to gather and analyses information.

Our data repository is continuously updated and revised by a team of research experts, so that it always reflects the latest trends and information. With a broad research and analysis capability, Transparency Market Research employs rigorous primary and secondary research techniques in developing distinctive data sets and research material for business reports.

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PEGylation is the process of covalently attaching polyethylene glycol (PEG) polymer chains to peptides. By increasing their molecular mass and shielding them from proteolytic enzymes, PEGylation improves the pharmacokinetics of peptides and proteins. PEGylation reduces renal clearance and results in more sustained absorption after subcutaneous administration, as well as restricted distribution. PEGylations have been shown to significantly improve water solubility, biocompatibility, immunogenicity, and other physico-chemical properties. It is an established