Multiple Myeloma Clinical Trials and Pipeline 2025: EMA, PDMA, FDA Approvals, Medication, NDA Approval, Therapies, ROA, MOA and Companies by DelveInsight

(Albany, United States) As per DelveInsight's assessment, globally, Multiple Myeloma pipeline constitutes 75+ key companies continuously working towards developing 80+ Multiple Myeloma treatment therapies, analysis of Clinical Trials, Therapies, Mechanism of Action, Route of Administration, and Developments analyzes DelveInsight.

"Multiple Myeloma Pipeline Insight, 2025" report by DelveInsight outlines comprehensive insights into the present clinical development scenario and growth prospects across the Multiple Myeloma Market.

The Multiple Myeloma Pipeline report embraces in-depth commercial and clinical assessment of the pipeline products from the pre-clinical developmental phase to the marketed phase. The report also covers a detailed description of the drug, including the mechanism of action of the drug, clinical studies, NDA approvals (if any), and product development activities comprising the technology, collaborations, mergers acquisition, funding, designations, and other product-related details.

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Some of the key takeaways from the Multiple Myeloma Pipeline Report:
• Multiple Myeloma Companies across the globe are diligently working toward developing novel Multiple Myeloma treatment therapies with a considerable amount of success over the years.
• Multiple Myeloma companies working in the treatment market are Poseida Therapeutics, Ionis Pharmaceuticals, CASI Pharmaceuticals, Sorrento Therapeutics, Cartesian Therapeutics, Rapa Therapeutics, Novartis, AbbVie, Pfizer, and others, are developing therapies for the Multiple Myeloma treatment
• Emerging Multiple Myeloma therapies in the different phases of clinical trials are- P-BCMACD19- ALLO1, ION251, CID-103, STI-1492, Descartes 08, RAPA-201, PHE885, Venetoclax, Elranatamab, and others are expected to have a significant impact on the Multiple Myeloma market in the coming years.
• In August 2024, Opna Bio, a Swiss biopharmaceutical company, has administered the first dose in a Phase I clinical trial of OPN-6602, an EP300/CBP bromodomain inhibitor intended for the treatment of multiple myeloma. The trial plans to enroll up to 130 participants with relapsed or refractory multiple myeloma at multiple locations across the U.S. The first dose was given at The START Center for Cancer Research in Grand Rapids, Michigan.
• In April 2024, Bristol Myers Squibb (NYSE: BMY) and 2seventy bio, Inc. (Nasdaq: TSVT) announced that on April 4, 2024, the U.S. Food and Drug Administration (FDA) approved Abecma® (idecabtagene vicleucel; ide-cel) for adults with relapsed or refractory multiple myeloma after at least two prior lines of therapy. These therapies must include an immunomodulatory agent (IMiD), a proteasome inhibitor (PI), and an anti-CD38 monoclonal antibody. This expanded approval, based on the KarMMa-3 trial, allows Abecma to be used earlier for patients exposed to all three treatment classes (triple-class exposed). Abecma is administered as a single infusion, with a newly recommended dose range of 300 to 510 x 106 CAR-positive T cells.

Multiple Myeloma Overview
Multiple myeloma is a type of blood cancer that affects plasma cells, a type of white blood cell found in the bone marrow. Plasma cells are responsible for producing antibodies that help fight infections. In multiple myeloma, these cells grow uncontrollably, crowding out normal blood cells and leading to weakened immunity, anemia, and bone damage.

The exact cause of multiple myeloma is unknown, but risk factors include older age, genetic predisposition, and exposure to certain chemicals or radiation. Common symptoms include bone pain, fatigue, frequent infections, kidney dysfunction, and high calcium levels.

Diagnosis typically involves blood tests, urine tests, bone marrow biopsy, and imaging studies like MRI or PET scans. The disease is classified into different stages based on the extent of organ involvement and the presence of genetic abnormalities.

Treatment options include chemotherapy, immunotherapy, targeted therapy, corticosteroids, and stem cell transplantation. While multiple myeloma remains incurable, advances in treatment have significantly improved survival rates and quality of life. Ongoing research continues to explore new therapies, including CAR-T cell therapy and bispecific antibodies, to provide better outcomes for patients.

Early detection and a personalized treatment approach play a crucial role in managing the disease effectively.

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Emerging Multiple Myeloma Drugs Under Different Phases of Clinical Development Include:
• P-BCMACD19- ALLO1: Poseida Therapeutics
• ION251: Ionis Pharmaceuticals
• CID-103: CASI Pharmaceuticals
• STI-1492: Sorrento Therapeutics
• Descartes 08: Cartesian Therapeutics
• RAPA-201: Rapa Therapeutics
• PHE885: Novartis
• Venetoclax: AbbVie
• Elranatamab: Pfizer

Multiple Myeloma Route of Administration
Multiple Myeloma pipeline report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs, such as
• Oral
• Intravenous
• Subcutaneous

Multiple Myeloma Molecule Type
Multiple Myeloma Products have been categorized under various Molecule types, such as
• Small molecule
• Cell Therapy
• Peptides
• Polymer
• Small molecule
• Gene therapy

Multiple Myeloma Pipeline Therapeutics Assessment
• Multiple Myeloma Assessment by Product Type
• Multiple Myeloma By Stage and Product Type
• Multiple Myeloma Assessment by Route of Administration
• Multiple Myeloma By Stage and Route of Administration
• Multiple Myeloma Assessment by Molecule Type
• Multiple Myeloma by Stage and Molecule Type

DelveInsight's Multiple Myeloma Report covers around 80+ products under different phases of clinical development like
• Late-stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I)
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates
• Route of Administration

Further Multiple Myeloma product details are provided in the report. Download the Multiple Myeloma pipeline report to learn more about the emerging Multiple Myeloma therapies at:
https://www.delveinsight.com/sample-request/multiple-myeloma-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr

Some of the key companies in the Multiple Myeloma Therapeutics Market include:
Key companies developing therapies for Multiple Myeloma are - Bristol-Myers Squibb Company, Takeda Pharmaceutical Company Limited, Amgen Inc., Sanofi S.A., Karyopharm Therapeutics Inc., Ono Pharmaceutical Co., Ltd., Novartis International, AGTeva Pharmaceutical Industries Ltd., Johnson and Johson, Inc. (Janssen Pharmaceuticals), AbbVie Inc., GlaxoSmithKline plc, Harpoon Therapeutics, and others.

Multiple Myeloma Pipeline Analysis:
The Multiple Myeloma pipeline report provides insights into
• The report provides detailed insights about companies that are developing therapies for the treatment of Multiple Myeloma with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for Multiple Myeloma Treatment.
• Multiple Myeloma key companies are involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Multiple Myeloma Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement and financing details for future advancement of the Multiple Myeloma market.
The report is built using data and information traced from the researcher's proprietary databases, company/university websites, clinical trial registries, conferences, SEC filings, investor presentations, and featured press releases from company/university websites and industry-specific third-party sources, etc.

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Multiple Myeloma Pipeline Market Drivers
• Rising prevalence of multiple myeloma worldwide, increasing investment for healthcare infrastructure are some of the important factors that are fueling the Multiple Myeloma Market.

Multiple Myeloma Pipeline Market Barriers
• However, high cost associated with the treatment of multiple myeloma, lack of healthcare infrastructure in developing economies and other factors are creating obstacles in the Multiple Myeloma Market growth.

Scope of Multiple Myeloma Pipeline Drug Insight
• Coverage: Global
• Key Multiple Myeloma Companies: Poseida Therapeutics, Ionis Pharmaceuticals, CASI Pharmaceuticals, Sorrento Therapeutics, Cartesian Therapeutics, Rapa Therapeutics, Novartis, AbbVie, Pfizer, and others
• Key Multiple Myeloma Therapies: P-BCMACD19- ALLO1, ION251, CID-103, STI-1492, Descartes 08, RAPA-201, PHE885, Venetoclax, Elranatamab, and others
• Multiple Myeloma Therapeutic Assessment: Multiple Myeloma current marketed and Multiple Myeloma emerging therapies
• Multiple Myeloma Market Dynamics: Multiple Myeloma market drivers and Multiple Myeloma market barriers

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Table of Contents
1. Multiple Myeloma Report Introduction
2. Multiple Myeloma Executive Summary
3. Multiple Myeloma Overview
4. Multiple Myeloma- Analytical Perspective In-depth Commercial Assessment
5. Multiple Myeloma Pipeline Therapeutics
6. Multiple Myeloma Late Stage Products (Phase II/III)
7. Multiple Myeloma Mid Stage Products (Phase II)
8. Multiple Myeloma Early Stage Products (Phase I)
9. Multiple Myeloma Preclinical Stage Products
10. Multiple Myeloma Therapeutics Assessment
11. Multiple Myeloma Inactive Products
12. Company-University Collaborations (Licensing/Partnering) Analysis
13. Multiple Myeloma Key Companies
14. Multiple Myeloma Key Products
15. Multiple Myeloma Unmet Needs
16 . Multiple Myeloma Market Drivers and Barriers
17. Multiple Myeloma Future Perspectives and Conclusion
18. Multiple Myeloma Analyst Views
19. Appendix
20. About DelveInsight

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