Press release
Key Driver Transforming The Primary Biliary Cholangitis Market 2025: Rising Smoking Rates Fuels Growth
Biliary Cholangitis Market
The global primary biliary cholangitis market reached a value of nearly $0.97 billion in 2024, having grown at a compound annual growth rate (CAGR) of 5.96% since 2019. The market is expected to grow from $0.97 billion in 2024 to $1.49 billion in 2029 at a rate of 8.88%. The market is then expected to grow at a CAGR of 8.73% from 2029 and reach $2.27 billion in 2034.
What strategies are being adopted by key players in the primary biliary cholangitis market?
The key players in the market are adopting extensive strategies in the primary biliary cholangitis market such as:
• Pursue orphan drug designation for the fixed-dose combination of OCA and bezafibrate in treating PBC
• Accelerate regulatory approval and market entry through orphan designation
• Introduce advanced ELISA serum tests to enhance diagnostic accuracy for PBC
• Improve patient outcomes with integrated therapeutic and diagnostic innovations
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To take advantage of opportunities, The Business Research Company suggests that Primary Biliary Cholangitis companies enhance offerings:
• Introduce innovative combination therapies to boost treatment efficacy and patient outcomes in liver cancer care
• Develop specialized orphan drugs combining obeticholic acid (OCA) and bezafibrates for PBC treatment
• Form strategic partnerships to accelerate the development of advanced treatments
What Is Primary Biliary Cholangitis: Market Definition?
Primary biliary cholangitis (PBC) is a chronic, progressive liver disease that primarily affects the bile ducts within the liver. It is an autoimmune condition in which the body's immune system mistakenly attacks the small bile ducts, leading to inflammation and scarring. Over time, this damage impairs bile flow, causing a buildup of toxic substances that can lead to liver fibrosis, cirrhosis and ultimately liver failure.
PBC is typically diagnosed through a combination of blood tests, imaging studies and liver biopsy. Blood tests help detect elevated liver enzymes, particularly alkaline phosphatase, as well as specific antibodies like antimitochondrial antibodies (AMA), which are present in most PBC cases. Imaging techniques such as ultrasound, magnetic resonance cholangiopancreatography (MRCP) and transient elastography (Fibroscan) are used to assess liver stiffness and bile duct abnormalities. In some cases, a liver biopsy may be performed to evaluate the degree of liver damage.
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Who Are The Major Companies Operating In The Global Primary Biliary Cholangitis Market?
The top ten competitors in the market made up to 50.90% of the total market in 2023. Intercept Pharmaceuticals Inc. was the largest competitor with a 35.63% share of the market, followed by:
• Mayo Clinic Laboratories
• University of Pittsburgh Medical Center (UPMC)
• Stanford Health Care
• Duke University Hospital
• UCLA Medical Center
• King's College Hospital
• NewYork-Presbyterian Hospital
• Cleveland Clinic
• Johns Hopkins Hospital
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The Business Research Company (www.thebusinessresearchcompany.com) is a leading market intelligence firm renowned for its expertise in company, market, and consumer research. We have published over 15,000 reports across 27 industries and 60+ geographies. Our research is powered by 1,500,000 datasets, extensive secondary research, and exclusive insights from interviews with industry leaders.
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