Press release
Primary Biliary Cholangitis Treatment Market
DataM Intelligence.com
Global Primary Biliary Cholangitis Treatment Market Expected to Reach US$ YY Million by 2030, Growing at a CAGR of YY%: Market Insights and Dynamics
The Global Primary Biliary Cholangitis Treatment Market, which reached US$ YY billion in 2022, is anticipated to achieve US$ YY million by 2030, exhibiting a robust CAGR of YY% during the forecast period from 2024 to 2031.
Primary Biliary Cholangitis (PBC), formerly known as primary biliary cirrhosis, is an autoimmune disorder causing progressive destruction of intrahepatic bile ducts, leading to periportal inflammation and cholestasis. This condition results in cirrhosis and portal hypertension, emphasizing the crucial role of an interprofessional team in recognizing and managing patients with PBC.
The pathogenesis of PBC is believed to involve a combination of genetic predisposition and environmental triggers. Strong familial prevalence, especially in first-degree relatives, underscores the genetic component, with a noteworthy odds ratio of 11. Notably, specific human leukocyte antigen (HLA) allele associations, such as DRB1, DR3, DPB1, DQA1, and DQB1, contribute to the understanding of PBC's genetic underpinnings.
Market Scope and Metrics:
CAGR: YY%
Size Available for Years: 2021-2030
Forecast Period: 2024-2031
Data Availability: Value (US$ Mn)
Segments Covered: Stage Type, Drug Type, Route of Administration, Distribution Channel
Regions Covered: North America, Europe, Asia-Pacific, South America, Middle East & Africa
Fastest Growing Region: Asia-Pacific
Largest Region: North America
Report Insights Cover:
Competitive Landscape Analysis, Company Profile Analysis, Market Size, Share, Growth, Demand, Recent Developments, Mergers and Acquisitions, New Product Launches, Growth Strategies, Revenue Analysis, Porter's Analysis, Pricing Analysis, Regulatory Analysis, Supply-Chain Analysis, and Other Key Insights.
To know more Insights Download Sample : https://www.datamintelligence.com/download-sample/primary-biliary-cholangitis-treatment-market
Market Dynamics: Drivers and Restraints
The primary driver for market growth is the increasing R&D investments in developing new drug therapeutics for PBC. While there is no cure for PBC, ongoing research has led to promising treatments like seladelpar and elafibranor, currently in advanced clinical trials. Positive results from CymaBay Therapeutics Inc.'s Phase 3 pivotal RESPONSE study of seladelpar in September 2023 exemplify these advancements.
Other factors contributing to market growth include the rise in PBC prevalence, advancements in treatment, and increased awareness. However, complications associated with untreated PBC, such as osteoporosis and an increased risk of liver cancer, present restraints. Additionally, limited treatment options and lack of awareness hinder market growth.
Market Segment Analysis:
The global PBC market is segmented by stage type, drug type, route of administration, distribution channel, and region. Ursodeoxycholic acid (UDCA) dominates the drug type segment, accounting for 41.2% of the market share. It is expected to maintain this dominance throughout the forecast period.
For instance, Ipsen and GENFIT reported positive topline data from the pivotal ELATIVE Phase III trial for elafibranor in June 2023, demonstrating its efficacy and safety.
Geographical Analysis:
North America accounted for approximately 38.4% of the market share in 2022 and is projected to maintain its dominance. Factors such as a well-established healthcare infrastructure, the presence of key market players, and recent product launches contribute to the region's significant market share.
In July 2023, Gannex Pharma completed the enrollment of 98 patients with PBC in the Phase II clinical trial of ASC42, a novel Farnesoid X receptor (FXR) agonist, showcasing continued advancements in the region.
COVID-19 Impact Analysis:
The COVID-19 pandemic initially negatively impacted the PBC therapeutics industry, disrupting research activities and clinical trials. However, with the easing of lockdowns, companies have resumed operations to meet the growing demand for PBC therapeutics. Increased product approvals and research and development efforts drive market growth despite the initial setbacks.
Competitive Landscape:
Major global players in the PBC market include Intercept Pharmaceuticals, Inc., Ice Pharma, Sun Pharma, Wellona Pharma, Zoic Life Sciences, Steris Healthcare, Cadila Pharma, Cipla, Brunet, AstraEureka Pharmaceuticals, and others.
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DataM Intelligence 4Market Research is a Market Research and Consulting firm that provides end-to-end business solutions to organizations from Research to Consulting. We, at DataM Intelligence, leverage our top trademark trends, insights and developments to emancipate swift and astute solutions to clients like you. We encompass a multitude of syndicate reports and customized reports with a robust methodology.
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