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Key Trend Reshaping the Daratumumab Or Darzalex Market in 2025: Focus On Transmembrane Proteins And Enhanced Treatment Solutions

02-18-2025 06:21 AM CET | Health & Medicine

Press release from: The Business Research Company

Daratumumab Or Darzalex Market

Daratumumab Or Darzalex Market

What Are the Projections for the Size and Growth Rate of the Daratumumab Or Darzalex Market?
The market for daratumumab, also known as darzalex, has experienced swift expansion in the last few years. It is projected to escalate from $5,093.04 million in 2024 to $5,618.30 million in 2025 with a compound annual growth rate (CAGR) of 10.3%. This substantial growth during the historic period is primarily due to the use of varied research avenues, the growing feasibility of biomanufacturing operations, a rise in the application of monoclonal antibodies, an increase in strategic initiatives, and a surge in the production of mAbs.

In the coming years, the market size for Daratumumab, also known as Darzalex, is projected to experience substantial growth. It is forecasted to expand to $8,189.36 million by 2029, with a compound annual growth rate (CAGR) of 10.0%. This growth within the projection period can be linked to factors such as increased clinical evidence, earlier adoption in treatment, rising demand for biologics, an increase in patient awareness, an increase in blood cancer cases, and the escalating prevalence of chronic illnesses. The forecast period is also likely to witness trends such as technological innovations, the launching of new products, product and/or service offerings, forming of partnerships, mergers and acquisitions, advancements in radiation technologies, and collaborative efforts.

What Are the Main Catalysts for Growth in the Daratumumab Or Darzalex Market?
The escalating prevalence of bone marrow cancer is projected to stimulate the progress of the Daratumumab or Darzalex market. Bone marrow cancer covers cancers initiated in the bone marrow, like multiple myeloma and leukemia, which tend to disturb normal body functions due to abnormal blood cell production. The increasing occurrence of these cancers is primarily due to an aging demographic, enhanced diagnostic techniques, and factors such as environmental effects, lifestyle decisions, and genetic propensities. Daratumumab, commonly known as Darzalex, contributes to the treatment of multiple myeloma, a variety of bone marrow cancer. It achieves this by concentrating on and eliminating abnormal plasma cells within the bone marrow. For example, in January 2024, the American Cancer Society, a non-profit organization committed to cancer eradication, projected the number of lymphoma cases to be 89,190, a slight rise from 89,010 in 2022. Additionally, myeloma cases are projected to rise to 35,780 from 34,470 in 2022. Therefore, the escalating cases of bone marrow cancer are fuelling the expansion of the daratumumab or darzalex market. Unprecedented increase in the application of targeted therapies and biologics is spurring the progress of the daratumumab or darzalex market. Targeted therapies denote a unique kind of medicinal treatment that employs drugs or other substances to accurately pinpoint and assault specific molecules actively involved in the growth and survival of cancer or other diseases. There is increased acceptance of biologics and targeted therapies due to the growing rate of chronic illnesses and advancements in precision medicine. These advancements provide more personalized and impactful treatments. Daratumumab is used in targeted therapies due to its definitive action on CD38, a protein that is highly present on the surface of harmful plasma cells in multiple myeloma. For instance, in December 2023, reports from Advanced Therapy Treatment Centers (ATTC), a network based in the UK which aims to deliver innovative and advanced therapy medicinal products (ATMPs) to patients, indicated a 31% upsurge in annual investments in advanced therapies compared to 2022, with the UK presently contributing to 14% of all global commercial ATMP clinical trials. Consequently, the swelling adoption of biologics and targeted therapies is fuelling the expansion of the daratumumab or darzalex market.

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Which Businesses Are at the Forefront of Daratumumab Or Darzalex Market Development?
Major companies operating in the daratumumab or darzalex market include Genmab A/S, Janssen Biotech Inc.

What Are the Latest Innovations in the Daratumumab Or Darzalex Market?
A significant trend in the daratumumab or darzalex market is the shift towards early-intervention measures for cancer treatment, like the adoption of combination therapies for an enhanced effectiveness against multiple myeloma and other types of cancer. Combination therapies encompass treatment approaches that utilize more than one therapeutic agent with differing action mechanisms, typically in a synergistic fashion, to amplified effectiveness, decrease resistance, and potentially amplify patient outcomes while likely lowering adverse side effects compared to singular therapy. One illustration of this in practice is in July 2024, when US-based pharmaceutical firm Johnson & Johnson gained US FDA approval for DARZALEX FASPRO (daratumumab and hyaluronidase-fihj) to be used concurrently with bortezomib, lenalidomide, and dexamethasone (D-VRd) for the initial and consolidation therapy of patients with newly diagnosed multiple myeloma (NDMM) who are suitable for autologous stem cell transplants (ASCT). This fresh approval introduces a fourfold therapy option at the time of the initial diagnosis, potentially leading to better patient outcomes.

How Is the Daratumumab Or Darzalex Market Segmented?
The daratumumab or darzalexmarket covered in this report is segmented -

1) By Drug Type: 100Mg Injection; 400Mg Injection
2) By Distribution Channel: Pharmacies; Hospital; Other Distribution Channels
3) By Application: Follicular Lymphoma; Mantle Cell Lymphoma; Multiple Myeloma; Diffuse Large B Cell Lymphoma; Other Applications

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Where Is the Daratumumab Or Darzalex Market Growth Most Prominent?
North America was the largest region in the daratumumab or darzalex market in 2024. The regions covered in the daratumumab or darzalex market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa.

What Is Covered In The Daratumumab Or Darzalex Global Market Report?

- Market Size Analysis: Analyze the daratumumab or darzalex Market Size by key regions, countries, product types, and applications.
- Market Segmentation Analysis: Identify various subsegments within the daratumumab or darzalex market for effective categorization.
- Key Player Focus: Focus on key players to define their market value, share, and competitive landscape.
- Growth Trends Analysis: Examine individual growth trends and prospects in the Market.
- Market Contribution: Evaluate contributions of different segments to the overall daratumumab or darzalex market growth.
- Growth Drivers: Detail key factors influencing market growth, including opportunities and drivers.
- Industry Challenges: Analyze challenges and risks affecting the daratumumab or darzalex market.
- Competitive Developments: Analyze competitive developments, such as expansions, agreements, and new product launches in the market.

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