Obesity-Related Factors Fueling Growth In The Cartilage Degeneration Market: Major Factor in the Transformation of the Cartilage Degeneration Market in 2025

How Will the Cartilage Degeneration Market Grow, and What Is the Projected Market Size?
The market size of cartilage degeneration has seen robust growth in the recent past. From $12.63 billion in 2024, it is predicted to expand to $13.4 billion in 2025, with a compound annual growth rate (CAGR) of 6.2%. The surge experienced during the historic period is credited to factors such as an aging population, incidents of joint injuries, the obesity crisis, sporting injuries, and limited self-repair capacity.

It is projected that the market size for cartilage degeneration will enjoy robust growth in the coming years. The market is set to soar to $16.62 billion by 2029, clocking a compound annual growth rate (CAGR) of 5.5%. This growth during the forecast period can be linked to progress in regenerative medicine, the use of biologic injections, precision medicine advancements, innovations in tissue engineering and the introduction of robotics-assisted surgery. The forecast period will see the rise of several trends including stem cell therapies, the use of 3D printing in orthopedics, gene therapy for repairing cartilage, personalized rehabilitation schemes, and the use of telemedicine for subsequent care.

What Key Elements Are Boosting Growth in the Cartilage Degeneration Market?
The surge in obesity rates is anticipated to drive the expansion of the cartilage degeneration market. Obesity is a health condition defined by an inordinate collection of body fat that could potentially damage an individual's health. Obesity can trigger and hasten cartilage degeneration by heightening cartilage compressive forces and inflammatory cytokines. Obesity stimulates numerous pathological shifts in the entire knee joint structure, including abnormal joint load, joint misalignment, and muscle frailty. For example, as per the Government Digital Service, a government entity in the UK, from 2021 to 2022, nearly 63.8% of adults aged 18 and above were either overweight or struggling with obesity, a rise from 63.3% from the year before. In addition, among adults, it was estimated that 25.9% were obese, showing an increase of 25.2% from 2020 to 2021. Consequently, the escalating prevalence of obesity is pushing the cartilage degeneration market's growth.

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Who Are the Major Industry Players Fueling Cartilage Degeneration Market Expansion?
Major companies operating in the cartilage degeneration market report are Johnson & Johnson Services Inc., MEDIPOST Co. Ltd., Medtronic PLC, Stryker Corporation, Zimmer Biomet Holdings Inc., Smith and Nephew PLC, B Braun Melsungen AG, Osiris Therapeutics Inc., Arthrex Inc., Conmed Corporation, Orthocell Ltd., Bioventus LLC, Aesculap Inc., Vericel Corporation, Anika Therapeutics Inc., Geistlich Pharma AG, MatTek Corporation, Breg Inc., Isto Biologics Inc., OrthoTrophix LLC, CellGenix GmbH, CartiHeal Inc., Cayenne Medical Inc., Collagen Solutions PLC, Regentis Biomaterials Ltd., Histogen Inc., BioTime Inc., CollPlant Holdings Ltd.

Which Key Developments Are Influencing the Cartilage Degeneration Market?
Leading corporations in the cartilage degeneration industry are designing groundbreaking products such as Agili-C to enable bone restructuring and cartilage renewal. Agili-C is a readily accessible, cell-free implant utilized for mending cartilage and osteochondral malformations in injury-induced and osteoarthritic joints. For example, CartiHeal Ltd., an Israel-situated medical appliance firm, unveiled its initial commercial insertion of Agili-C in July 2023. The implant's primary objective involves promoting the innate regenerative process for articular cartilage and subchondral bone, rather than depending on cells or growth elements. The implant incorporates natural calcium carbonate or aragonite, procured from coral's outer structure. It urges chondrocytes from the adjacent cartilage to shift into the structure, where they deposit an extracellular matrix. This approval serves as a testimony for the implant, ensuring patients and healthcare professionals of its safety and efficacy as a treatment alternative.

How Is the Segmentation of the Cartilage Degeneration Market Defined?
The cartilage degeneration market covered in this report is segmented -

1) By Procedure: Joint Replacements, Chondroplasty, Osteochondral Transplants, Microfracture, Meniscus Transplants, Cell-Based Cartilage Resurfacing, Autologous Chondrocyte Implantation, Other Procedures
2) By Application: Knee, Hip, Other Applications
3) By End User: Hospitals And Specialty Clinics, Ambulatory Surgical Centers, Academic And Research Institutes

Subsegments:
1) By Joint Replacements: Knee Replacement (Partial, Total), Hip Replacement (Partial, Total), Shoulder Replacement (Total, Reverse), Other Joints (Ankle, Elbow, Wrist)
2) By Chondroplasty: Radiofrequency Ablation Chondroplasty, Mechanical Chondroplasty, Thermal Chondroplasty, Arthroscopic Chondroplasty
3) By Osteochondral Transplants: Autografts (OATS), Allografts (Fresh Osteochondral Allografts), Synthetic Implants
4) By Microfracture: Traditional Microfracture, Augmented Microfracture (with scaffolds or matrix implants)
5) By Meniscus Transplants: Allograft Meniscus Transplantation (Cryopreserved, Fresh Frozen), Synthetic Meniscus Implants
6) By Cell-Based Cartilage Resurfacing: Autologous Cell-Based Therapy, Allogeneic Cell-Based Therapy, Stem Cell-Based Cartilage Repair
7) By Autologous Chondrocyte Implantation (ACI): First-Generation ACI, Second-Generation ACI, Third-Generation ACI (MACI)
8) By Other Procedures: Arthroscopic Debridement, Osteotomy, Cartilage Repair Using Synthetic Scaffolds, Injection-Based Therapies (Hyaluronic Acid, PRP, Stem Cell Injections)

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What Is the Leading Region in the Cartilage Degeneration Market?
North America was the largest region in the cartilage degeneration market in 2023. Asia-Pacific is expected to be the fastest-growing region in the forecast period. The regions covered in the cartilage degeneration market report are Asia-Pacific, Western Europe, Eastern Europe, North America, South America, Middle East, Africa

What Is Covered In The Cartilage Degeneration Global Market Report?

- Market Size Analysis: Analyze the Cartilage Degeneration Market size by key regions, countries, product types, and applications.
- Market Segmentation Analysis: Identify various subsegments within the Cartilage Degeneration Market for effective categorization.
- Key Player Focus: Focus on key players to define their market value, share, and competitive landscape.
- Growth Trends Analysis: Examine individual growth trends and prospects in the Market.
- Market Contribution: Evaluate contributions of different segments to the overall Cartilage Degeneration Market growth.
- Growth Drivers: Detail key factors influencing market growth, including opportunities and drivers.
- Industry Challenges: Analyze challenges and risks affecting the Cartilage Degeneration Market.
- Competitive Developments: Analyze competitive developments, such as expansions, agreements, and new product launches in the market.

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