Press release
LBP Innovation Acceleration: Creative Biolabs' Integrated Analysis and Validation Platform
According to the experts at Creative Biolabs, LBP commercialization will become a clever strategy in systems biology which they are ready to embrace with full technological capabilities.New York, USA - November 11, 2024 - Pharmaceutical and research organizations across the world have taken a particular interest in live biotherapeutic products (LBPs) with various applications such as immunotherapy or antibacterial therapies due to their unique characteristics.
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Microbial Identification
Within the life cycle of developing LBPs, the most important step includes microbial identification. Traditional microbial identification techniques are restricted by culture methods, resulting in an inability to isolate and accurately identify all microorganisms present in complex samples.
"Traditional methods of identification came up short," said an expert from Creative Biolabs. "We have adopted genome-based identification methods that include, among others, 16S rRNA sequencing [https://live-biotherapeutic.creative-biolabs.com/16s-rrna-gene-in-microbial-molecular-identification.htm], which is fast, accurate, and avoids constraints posed by traditional identification methods."
Microbial identification is often a routine and simple activity performed at many clinical microbiology laboratories, but it is believed that 16S rRNA sequencing has reduced ambiguity and is much more accurate. Creative Biolabs employs this method to perform identifications through sequence analysis. In comparison to traditional cultivation procedures, PCR-based 16S rRNA sequencing is a rapid and sensitive approach for detecting difficult-to-culture microorganisms.
In addition, Creative Biolabs also uses high-throughput microarray-based methods [https://live-biotherapeutic.creative-biolabs.com/community-analysis-using-high-throughput-microarray-based-method.htm] to achieve bacterial detection. A large amount of bacteria can be detected efficiently, and researchers will save time when performing massive screenings. This rapid advancement allows for much more efficient and shorter timelines while screening out a large number of variables.
Gene Integration Stability
As for how to test gene integration stability in recombinant strains [https://live-biotherapeutic.creative-biolabs.com/gene-integration-stability-test-for-recombinant-strains.htm], Creative Biolabs is also above average here. Stability of gene integration is one of the key determinants in the evaluation of the safety and efficacy of LBPs. Renowned, "This service is excellent for the development of LBPs when gene stability is critical, as it would help to address probably problems during the time of development and avert low quality or failures later on in the process."
In this area, Creative Biolabs offers a range of techniques for determination of transgene integration sites' genetic stability, including transgene sequencing analysis, structure analysis by Southern blot, gene insertion and copy number by qPCR, and transcript analysis by RT-PCR and northern blot.
According to the expert, "We know that the development of LBPs is associated with a lot of challenges and complexities; hence, we are trying to diversify our technical platform to reduce time and cost in the development of the product without compromising product quality and stability."
For LBP development solutions, please check https://live-biotherapeutic.creative-biolabs.com.
About Creative Biolabs
Using its advanced technologies, Creative Biolabs has supported global biopharmaceutical companies in microbial identification and gene integration stability testing. In the future, Creative Biolabs will still remain focused on the development of biopharmaceuticals and innovate their products for better convenience and efficiency.
Media Contact
Company Name: Creative Biolabs
Contact Person: Candy Swift
Email: Send Email [http://www.universalpressrelease.com/?pr=lbp-innovation-acceleration-creative-biolabs-integrated-analysis-and-validation-platform]
Phone: 1-631-830-6441
Country: United States
Website: https://live-biotherapeutic.creative-biolabs.com
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