Advancements in Gaucher's Disease Treatment Drive Market Growth to $2.08 Billion by 2028: Rising Prevalence of Genetic Abnormalities Boosts Market

The gaucher's disease market size has grown strongly in recent years. It will grow from $1.58 billion in 2023 to $1.68 billion in 2024 at a compound annual growth rate (CAGR) of 6.2%. The growth in the historic period can be attributed to enzyme replacement therapy (ert) development, increasing disease awareness, genetic research and diagnosis, patient advocacy initiatives, government incentives for rare diseases.

The gaucher's disease market size is expected to see strong growth in the next few years. It will grow to $2.08 billion in 2028 at a compound annual growth rate (CAGR) of 5.5%. The growth in the forecast period can be attributed to next-generation therapies, global patient registry expansion, improvements in access to treatment, personalized medicine approaches, regulatory support for rare diseases. Major trends in the forecast period include technological innovations in treatment monitoring, international collaborations in research, oral therapeutics advancements, expanded newborn screening programs, global collaboration for patient access.

Market Overview -
Gaucher's disease is a rare genetic disorder that interferes with the metabolism of a particular kind of fat called glucocerebroside. This disorder is caused by the formation of a fatty substance called glucocerebroside within certain cells, particularly in the spleen, liver, bone marrow, and sometimes in the brain.

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Rising Prevalence Of Genetic Abnormalities Boost Gaucher Disease
The rising prevalence of genetic abnormalities is expected to propel the growth of the Gaucher's disease market going forward. Genetic abnormalities are changes or mutations that occur in the DNA sequence of a person's genes and may result in abnormal features, functions, or characteristics. The inheritance pattern of Gaucher's disease is autosomal recessive, which means that an individual must inherit two copies of the mutated GBA gene, one from each parent, to develop the disease. People with Gaucher's disease do not make enough of this enzyme, which leads to a buildup of fatty substances called lipids in certain organs such as the spleen and liver. For instance, in May 2021 according to MedlinePlus's report, a US-based online information service provider by the United States National Library of Medicine, syndrome A is identified in about 1 in 200,000 Americans each year and currently around 100,000 kids suffer from syndrome B, whereas, it is estimated nearly 12,000 people died globally from syndrome C in the year 2020 and approximately 1% of people in the United States develop disorder D during their lifetimes. Therefore, the rising prevalence of genetic abnormalities is driving the growth of the Gaucher's disease market.

Competitive Landscape -
Major companies operating in the gaucher's disease market report are Pfizer Inc., Johnson & Johnson, Merck and Co. Inc., Novartis AG, Sanofi S.A., Abbott Laboratories, GlaxoSmithKline plc, Takeda Pharmaceutical Company Limited, Moderna Inc., Teva Pharmaceutical Industries Ltd., Boehringer Ingelheim International GmbH, BioMarin Pharmaceutical Inc., CHIESI Farmaceutici SPA, IntraBio Inc., REGENXBIO Inc., JCR Pharmaceuticals Co. Ltd., Ultragenyx Pharmaceutical Inc., Amicus Therapeutics Inc., Pharming Group N.V., Idorsia Pharmaceuticals Ltd., Centogene N.V., Protalix BioTherapeutics, AVROBIO Inc., Resverlogix Corp., GenSight Biologics S.A., ISU Abxis Co. Ltd., SIRION BIOTECH GmbH, Greenovation Biotech GmbH, Orphazyme A/S

Increasing Focus On Technological Advancements To Drive The Revenues
Major companies operating in the Gaucher's disease market are developing innovative technologies such as NGS (next-generation sequencing) to better serve the patients. Next-generation sequencing (NGS), also known as high-throughput sequencing, is a revolutionary technology that allows rapid and cost-effective sequencing of DNA and RNA molecules. For instance, in February 2023, Eurofins Genomics LLC, a US-based biotechnology company, launched a whole plasmid sequencing service utilizing advanced Gen3 NGS (next-generation sequencing) technology. This revolutionary offering delivers rapid, same-day results with impressive single-base accuracy of up to 99%. By strategically combining the strengths of Sanger sequencing's accuracy and quick turnaround time with the comprehensive analysis capabilities of NGS, the whole plasmid sequencing service bridges the gap between these two methods. This service accommodates long DNA constructs from 2.5 to 300 kb. With this new approach, Eurofins Genomics US empowers researchers with a cost-effective, time-efficient solution for long-read sequencing, offering a unique blend of accuracy and speed in the realm of genetic analysis.

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Key Segments -
The gaucher's disease market covered in this report is segmented -
1) By Type: Gaucher Disease Type 1, Gaucher Disease Type 2, Gaucher Disease Type 3, Other Types
2) By Diagnosis: Physical Exam, Blood Tests, Imaging Tests, Preconception Screening and Prenatal Testing, Other Diagnoses
3) By Therapy: Enzyme Replacement Therapy, Substrate Reduction Therapy
4) By Route Of Administration: Oral, Parenteral, Other Routes Of Administration
5) By End User: Hospitals, Specialty Clinics, Homecare, Other End Users

Key highlights covered in the report -
1. Detailed market size forecast and historical data analysis
2. Key drivers influencing market growth
3. Identification of upcoming trends and potential opportunities in the market
4. Analysis of major players strategies, to understand competitive dynamics and market positioning
5. Evaluation of regional dynamics

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