Chronic Spontaneous Urticaria (CSU) Market to Register Incremental Growth Across the APAC Region by 2034 - DelveInsight | Key Companies - Sanofi, Regeneron, AstraZeneca, Allakos, Amgen, Roche, Novartis, GlaxoSmithKline, Eli Lilly

DelveInsight's "Chronic Spontaneous Urticaria (CSU) - Patient Pool Analysis, Market Size, and Market Forecast APAC, 2034" report provides comprehensive insights into the historical and projected patient burden, treatable patient population, and notable market trends across the APAC region (India, China, South Korea, Taiwan, and Australia), highlighting distinctions from established markets.

The APAC Chronic Spontaneous Urticaria market report also offers insights into current treatment patterns, emerging prominent players, market shares of approved drugs, and peak share estimates for upcoming therapies. It covers historical and forecasted Chronic Spontaneous Urticaria market size, share, and trends in the Asia-Pacific region (India, China, South Korea, Taiwan, and Australia) during the study period (2020-2034). Additionally, the report examines recent treatment practices, therapy compliance, and accessibility, identifying unmet needs and evaluating market potential.

Chronic Spontaneous Urticaria (CSU): An Overview
Urticaria is a common and heterogeneous inflammatory skin disorder with or without associated angioedema. It presents with wheals, angioedema, or both due to activation and degranulation of skin mast cells, followed by the release of histamine and other mediators leading to sensory nerve activation, vasodilatation, plasma extravasation, and cellular recruitment. It is classified as acute or chronic; acute urticaria is present for less than 6 weeks, while chronic urticaria lasts more than 6 weeks.

Chronic urticaria is further classified as chronic induced urticaria (CIndU) and chronic spontaneous urticaria (CSU). CIndU has definite and subtype-specific triggers that induce signs and symptoms, while Chronic Spontaneous Urticaria is endogenous and independent of external causes. Women are twice as likely as men to be diagnosed with the disease, and most people first develop symptoms between 20 and 40.

Chronic Spontaneous Urticaria can persist for months or even years but can also resolve spontaneously in many cases. The appearance of hives is unpredictable and can occur without a specific trigger. Chronic Spontaneous Urticaria is believed to involve immune system dysfunction, with activation of mast cells and release of histamine. Autoimmunity and other underlying factors may play a role in some cases.

The diagnosis of Chronic Spontaneous Urticaria is based on a thorough medical history, physical examination, and the exclusion of identifiable triggers or underlying causes. Additional tests may be conducted to rule out other conditions and assess for underlying autoimmune factors.

Chronic Spontaneous Urticaria (CSU) Market Outlook (APAC Region)
The market for Chronic Spontaneous Urticaria (CSU) in the Asia Pacific region is rapidly evolving with advancements in treatment options and collaborative efforts among healthcare professionals and stakeholders. Traditionally, managing CSU has been challenging, relying on symptomatic relief through antihistamines and corticosteroids. However, the emergence of targeted biologic therapies, like anti-IgE monoclonal antibodies, offers more effective and long-lasting relief for patients with refractory CSU. Improved diagnostic techniques, such as skin prick tests and specific biomarker blood tests, aid in accurate diagnosis and personalized treatment plans.

Collaboration among healthcare professionals, patient advocacy groups, and pharmaceutical companies is essential for raising awareness and advocating for access to innovative treatments. Despite challenges like limited access to specialized care and high treatment costs, efforts are underway to ensure comprehensive and timely care for individuals affected by CSU in the region. Overall, the evolving market for CSU in the Asia Pacific region offers hope for improved outcomes and quality of life for patients.

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Chronic Spontaneous Urticaria (CSU) Market
The Chronic Spontaneous Urticaria Market is poised for significant evolution, particularly within Asia-Pacific countries. This shift is underscored by the market outlook section of the report, which aims to enhance comprehension by delving into historical, present, and forecasted market projections. By examining the influence of both markets and emerging therapies, the report offers insights into the transformative forces at play. Furthermore, it conducts a thorough examination of the drivers, barriers, unmet needs, and emerging technologies within the Chronic Spontaneous Urticaria market landscape.

The report comprehensively outlines the market trends associated with every Chronic Spontaneous Urticaria drug currently available in the market and those in late-stage pipeline (i.e. Phase III stage) development. This thorough analysis encompasses various facets such as the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MOA), competitive landscape vis-à-vis other therapies, brand reputation, and their overall influence on the market dynamics. Furthermore, it incorporates insights from key opinion leaders, providing a holistic view of the market scenario.

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Chronic Spontaneous Urticaria (CSU) Epidemiology
The prevalence of Chronic Spontaneous Urticaria differs significantly across the APAC countries (India, China, South Korea, Taiwan, and Australia), influenced by a multitude of factors including genetics, demographics, lifestyle choices, and environmental elements. Within the report's epidemiology section, a comprehensive examination of patient burdens within each Asia-Pacific country is provided, encompassing historical, present, and projected trends. This analysis not only addresses the diagnosed and treated patient populations but also delves into sub-segments such as age-specific and gender-specific demographics, offering a nuanced understanding of the disease landscape within the region.

The Report Covers the Chronic Spontaneous Urticaria Epidemiology Segmented as -
• Type-specific Cases of Chronic Urticaria in the ASIA Pacific Region
• Gender-specific Cases of Chronic Spontaneous Urticaria in the ASIA Pacific Region
• Age-specific Cases of Chronic Spontaneous Urticaria in the ASIA Pacific Region
• Diagnosed Prevalent Cases of Chronic Urticaria in the ASIA Pacific Region
• Severity-specific Cases of Chronic Spontaneous Urticaria in the ASIA Pacific Region

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Chronic Spontaneous Urticaria (CSU) Drugs Uptake and Pipeline Development Activities
Numerous leading pharmaceutical and biotechnology firms are actively engaged in developing therapies for Chronic Spontaneous Urticaria. This section of the Chronic Spontaneous Urticaria market report offers detailed insights into each therapy approved within the APAC countries, provided the therapy retains patent protection or market exclusivity in at least one APAC nation. Notably, off-label, generic, and biosimilar treatments are consolidated within the preceding treatment section of the report. Within this section, both marketed and late-stage (Phase III and Phase II) pipeline drugs are scrutinized, while early-phase drugs are presented in tabular format for clarity and accessibility.

Every Chronic Spontaneous Urticaria drug chapter within the report will encompass a comprehensive overview, comprising detailed descriptions, clinical trial evaluations, insights into research and development initiatives, as well as analyses of agreements and collaborations pertinent to each drug. Moreover, the chapters will delve into approval status, patent particulars, and a thorough examination of the advantages and disadvantages associated with each drug. Additionally, the report covers the latest updates and news pertaining to each product, ensuring a well-rounded understanding of the current landscape surrounding these therapies.

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Chronic Spontaneous Urticaria (CSU) Therapeutics Assessment
The treatment of Chronic Spontaneous Urticaria is challenging, and the therapeutic goal is a reduction in disease activity, complete symptom control, and improvement in QoL. The current treatment regime aims to alleviate symptoms and prevent their recurrence. The treatment pattern typically involves a step-wise approach, starting with first-line treatments and progressing to more advanced options if necessary.

The initial treatment for Chronic Spontaneous Urticaria involves the use of H1-antihistamines. Further, other medications, including corticosteroids, leukotriene receptor antagonists, and XOLAIR (omalizumab), are prescribed for more severe or refractory cases. XOLAIR is the only approved monoclonal antibody indicated for treating Chronic Spontaneous Urticaria. It selectively binds to human immunoglobulin E (IgE) and lowers free IgE levels.

There are several unmet needs in Chronic Spontaneous Urticaria management, including developing more effective long-term treatment options, personalized approaches, improved understanding of underlying mechanisms, patient education, support, and increased accessibility to affordable treatments.

Several prominent pharma and biotech companies are actively engaged in developing therapies for Chronic Spontaneous Urticaria. Among these companies, several have progressed their Chronic Spontaneous Urticaria drug candidates to the most advanced stages, including pre-registration. One notable frontrunner in this domain is Sanofi. With its commitment to advancing Chronic Spontaneous Urticaria treatment options, Sanofi stands out as a leader in the development of therapies for this challenging condition. Additionally, numerous other pharmaceutical and biotech companies are diligently working on advancing their Chronic Spontaneous Urticaria drug candidates, collectively contributing to the expanding landscape of treatment options for individuals living with this chronic condition.

Leading Companies in the Chronic Spontaneous Urticaria (CSU) Therapeutics Market Include
Some of the key companies in the Chronic Spontaneous Urticaria Therapeutics Market include Sanofi, Regeneron, AstraZeneca, KyowaHakkoKirin, Allakos, BioWa, Amgen, Taiho Pharmaceutical, CelldexTherapeutics, Roche, Novartis, Kiniksa Pharmaceuticals, Ltd, United BioPharma, GlaxoSmithKline, Eli Lilly and Company, Teva Pharmaceuticals Development, Inc., Celltrion, MICRO BIOGROUP., Escient Pharmaceuticals, Jasper Therapeutics, Glenmark Pharmaceuticals, ValenzaBio, CarnaBiosciences, Servier, and others.

Emerging and Marketed Chronic Spontaneous Urticaria (CSU) Therapies Covered in the Report Include
• Barzolvolimab: Celldex Therapeutics
• Dupilumab: Sanofi/ Regeneron
• DUPIXENT (dupilumab): Sanofi/Regeneron
• Ligelizumab: Novartis Pharmaceuticals
• Lirentelimab (AK002): Allakos/BioWa
• Remibrutinib (LOU064): Novartis Pharmaceuticals
• Tezepelumab: Amgen
• XOLAIR (omalizumab): Roche/Novartis
And Many Others

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Table of Content (TOC)
1. Key Insights
2. Report Introduction
3. Market Overview at a Glance
4. Epidemiology and Market Methodology
5. Executive Summary
6. Key Events
7. Chronic Spontaneous Urticaria Disease Background and Overview
8. APAC Chronic Spontaneous Urticaria Patient Pool Analysis
9. APAC Chronic Spontaneous Urticaria Patient Journey
10. Marketed Chronic Spontaneous Urticaria Therapies
11. Emerging Chronic Spontaneous Urticaria Therapies
12. Chronic Spontaneous Urticaria APAC Market Analysis
13. Access and Reimbursement Scenario
14. KOL's Views on Chronic Spontaneous Urticaria Market
15. SWOT Analysis
16. Unmet Needs
17. Appendix
18. DelveInsight Capabilities
19. Disclaimer
*The table of contents is not exhaustive; the final content may vary.

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