Alopecia Areata Market Size in the 7MM is going to be ~USD 552 million in 2025, and expected to grow with a CAGR of 18.5% by 2034, estimates DelveInsight

DelveInsight's "Alopecia Areata Market Insight, Epidemiology, and Market Forecast - 2034" report delivers an in-depth understanding of desmoid tumor, historical and forecasted epidemiology as well as the Alopecia Areata market trends in the United States, EU4 (Germany, France, Italy, and Spain) and the United Kingdom, and Japan.

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Key Takeaways from the Alopecia Areata Market Report
• In 2023, the US accounted for the highest prevalence of alopecia areata with approximately 764 thousand cases, which are expected to increase by 2034 at a CAGR of 1.4%.
• In 2023, the UK reported the highest number of diagnosed prevalent cases of alopecia areata among the EU4 and the UK, with approximately 323 thousand cases. Spain followed with around 170 thousand cases, while Italy recorded the lowest diagnosed prevalence, with nearly 100 thousand cases.
• In 2023, Japan reported approximately 167 thousand diagnosed prevalent cases of alopecia areata in females and 107 thousand cases in males, with numbers projected to rise by 2034.
• In 2023, females accounted for 63% of alopecia areata cases in the EU4 and the UK, while males represented 37%. These gender-specific patterns are expected to grow, with overall prevalence projected to increase by 2034.
• In Germany, approximately 89% of alopecia areata cases in 2023 occurred in individuals before 40 age group, while 11% were observed in those above 40 age group, indicating higher susceptibility among the before 40 age group.
• In 2023, around 14% of alopecia areata cases in the EU4 and the UK were mild, 45% moderate, and 41% severe. These severity patterns are expected to continue, with overall prevalence anticipated to increase by 2034.
• The leading Alopecia Areata Companies such as Eli Lilly and Company, Pfizer, Incyte Corporation, Sun Pharmaceuticals, and others.
• Promising Alopecia Areata Therapies such as OLUMIANT (baricitinib), LITFULO (ritlecitinib), Etrasimod, Coacillium (LH-8), PF-06651600, ADX-914, Upadacitinib, Daxdilimab, CTP-543, Deucravacitinib, SHR0302, IMG-007, Jaktinib, Rezpegaldesleukin, Rosnilimab, LEO 124249, Baricitinib, and others

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Alopecia Areata Epidemiology Segmentation in the 7MM
• Total Prevalence of Alopecia Areata
• Prevalent Cases of Alopecia Areata by severity
• Gender-specific Prevalence of Alopecia Areata
• Diagnosed Cases of Episodic and Chronic Alopecia Areata

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Marketed Alopecia Areata Drugs
• OLUMIANT (Baricitinib): Eli Lilly and Company/Incyte Corporation
OLUMIANT is a selective and reversible JAK inhibitor that targets the cytokine signaling pathway associated with alopecia areata. It works by inhibiting the activation of ATPase on JAK, blocking signal transmission to cells via the Signal Transducer and Activator of Transcription (STAT) pathway. This mechanism disrupts inflammation and immune responses involved in the condition. OLUMIANT, acting as a JAK inhibitor, has received regulatory approval in the US, EU, and Japan for the treatment of severe alopecia areata.

• LITFULO (Ritlecitinib): Pfizer
LITFULO (ritlecitinib), developed by Pfizer, is an innovative FDA-approved oral treatment for severe alopecia areata, an autoimmune disorder causing significant hair loss. It works by targeting JAK3 and TEC inhibitors to disrupt immune pathways responsible for hair follicle destruction. LITFULO has been approved for use in the US, EU, and Japan, addressing the needs of individuals aged 12 and older with severe forms of the condition. It also received breakthrough designation, highlighting its potential to transform alopecia areata treatment.

• LEQSELVI (Deuruxolitinib, CTP 543): Sun Pharmaceuticals
LEQSELVI (Deuruxolitinib), developed by Sun Pharmaceutical Industries, is an FDA-approved oral treatment for severe alopecia areata in adults. It works by inhibiting JAK1and JAK2, targeting immune pathways that contribute to hair loss in the condition. LEQSELVI is taken once daily and has received breakthrough and fast track designation for alopecia areata. This approval provides a new treatment option for individuals with severe alopecia areata, offering hope for those affected by this autoimmune disorder.

Alopecia Areata Emerging Drugs
• RINVOQ (Upadacitinib): AbbVie
RINVOQ (upadacitinib), a JAK1-specific oral inhibitor, shows promise for alopecia areata treatment, despite being primarily approved for rheumatoid arthritis and atopic dermatitis. Clinical studies indicate significant hair regrowth and improved quality of life. Currently in Phase III, RINVOQ is projected for alopecia areata approval by 2027.

• Bempikibart (ADX-914): Q32 Bio
Bempikibart (ADX-914) is a fully human antibody that targets the IL-7 Receptor Alpha subunit (IL-7Ra) and Thymic Stromal Lymphopoietin (TSLP), aiming to regulate immune function in autoimmune diseases. Currently in Phase II trials for alopecia areata, both IL-7 and TSLP pathways are linked to T-cell-mediated processes in autoimmune conditions. Q32 Bio has completed enrollment for the Phase II trial.

• Amlitelimab (SAR-445229): Sanofi
Amlitelimab (SAR-445229) is a monoclonal antibody targeting OX40L, a molecule that activates T cells driving autoimmune responses. By blocking the OX40-OX40L pathway, it reduces inflammation and regulates the immune system without widespread immunosuppression. Currently in Phase II trials for alopecia areata, it shows potential as a targeted, effective alternative to traditional immunosuppressive therapies.

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Alopecia Areata Market Outlook
Alopecia areata is a chronic autoimmune disorder causing non-scarring hair loss, often starting as patchy bald spots on the scalp but potentially affecting other hair-bearing areas. The immune system attacks hair follicles, disrupting growth cycles. The condition can range from localized patches to complete hair loss (alopecia totalis or universalis). Genetic and environmental factors contribute to its onset. Besides physical effects, alopecia areata significantly impacts emotional well-being and quality of life.

Alopecia Areata Treatment Market
The Alopecia Areata Treatment Market has evolved to incorporate a comprehensive approach, combining medications with supportive care. The market offers a range of therapies, including corticosteroids, immunosuppressants, immunomodulators, and topical sensitizers or irritants. Corticosteroids remain central for their anti-inflammatory properties, reducing immune attacks on hair follicles, while immunosuppressants and immunomodulators are used in more severe or resistant cases to regulate the immune system and prevent further hair loss.

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Scope of the Alopecia Areata Market Report
• Coverage- 7MM
• Study Period- 2020-2034
• Alopecia Areata Companies- Eli Lilly and Company, Pfizer, Incyte Corporation, Sun Pharmaceuticals, and others.
• Alopecia Areata Therapies- OLUMIANT (baricitinib), LITFULO (ritlecitinib), Etrasimod, Coacillium (LH-8), PF-06651600, ADX-914, Upadacitinib, Daxdilimab, CTP-543, Deucravacitinib, SHR0302, IMG-007, Jaktinib, Rezpegaldesleukin, Rosnilimab, LEO 124249, Baricitinib, and others
• Alopecia Areata Market Dynamics: Alopecia Areata Market Drivers and Barriers
• Alopecia Areata Market Access and Reimbursement, Unmet Needs and Future Perspectives

Table of Contents
1. Key Insights
2. Alopecia Areata Market Report Introduction
3. Alopecia Areata Executive Summary
4. Key Events
5. Alopecia Areata Epidemiology and Market Forecast Methodology
6. Alopecia Areata Market Overview at a Glance
7. Alopecia Areata Market Disease Background and Overview
8. Guidelines
9. Epidemiology and Patient Population of Alopecia Areata in the 7MM
10. Alopecia Areata Patient Journey
11. Alopecia Areata Marketed Drugs
12. Alopecia Areata Emerging Drugs
13. Alopecia Areata: 7MM Analysis
14. Alopecia Areata Unmet Needs
15. Alopecia Areata SWOT Analysis
16. Alopecia Areata KOL Views
17. Alopecia Areata Market Access and Reimbursement
18. Appendix
19. DelveInsight Capabilities
20. Disclaimer
21. About DelveInsight

About Us

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