Press release
mRNA Manufacturing and Synthesis Services Market Current Scenario with Future Aspect Analysis
The mRNA Synthesis and Manufacturing Services Market Size is valued at USD 49,152.2 Million in 2022 and is predicted to reach USD 51,603.6 Million by the year 2031 at a 0.8% CAGR during the forecast period for 2023-2031.
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During the forecast period (2022-2031), the global mRNA Manufacturing and Synthesis services market is projected to reach US$ 22,634.5 Million in 2031, at a CAGR of -3.4% from US$ 53,278.8 Million in 2021. Due to the success of the COVID-19 vaccines, the demand for a steady supply of vaccines has skyrocketed in 2021, causing the market to expand exponentially. In 2022, the market is anticipated to decline by -42.0%. Besides the COVID-19 application, the mRNA Synthesis and Manufacturing Services market is developing, presenting enormous growth and penetration opportunities over the forecast period.
mRNA vaccines for Malaria, Influenza virus, Hemorrhagic fever virus, Genital herpes virus, and Lyme disease, among others, have a robust pipeline and are anticipated to be launched during the forecast period.
Asia-Pacific dominated the market in 2021 with a 33.4% market share due to the enormous demand for the COVID-19 vaccine. The potential for low-cost manufacturing, improved immunogenicity, higher effectiveness of mRNA vaccine compared to other vaccine technologies, and constant R&D innovations & developments in mRNA Manufacturing and Synthesis services are expected to drive market growth over the forecast period.
In addition, the rising number of clinical trials for cancer therapies, the growing burden of infectious diseases, and novel innovations by pharmaceutical CDMO companies are likely to support the growth of mRNA Manufacturing and Synthesis services market in the forecast period. However, maintaining the high stability and purity of the mRNA products is a significant challenge faced by the manufacturers.
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Geographically, the North American and Asia Pacific region is the primary revenue pocket of this market due to high demand and raising awareness about mRNA vaccines, increasing government investments in the R&D to treat infectious diseases.
The key CDMO organizations operating in the mRNA Manufacturing and Synthesis services market are eTheRNA (Etherna Immunotherapies), Celonic AG, Corden Pharma GmbH, Lonza Group AG, Rentschler Biopharma, Laboratorios Farmacéuticos Rovi, S.A., Samsung Biologics, Thermo Fisher Scientific, Sartorius (BIA Separations) among others
Noticeably Custom Synthesis/Other Service Providers are Eurogentec, Aldevron, bioSYNTHESIS, TriLink BioTechnologies, Biomay, Jena Biosciences, APExBIO, CELLSCRIPT, New England Biolabs, Kernal Biologics, Cytiva, among others
Foremost leaders in Therapeutics and Vaccine Developers are CureVac, Moderna, BioNTech (Pfizer), Translate Bio, Ethris (AstraZeneca), Silence Therapeutics, Tiba Biotechnology, In-Cell-Art, Anima Biotech, H3 Biomedicine Inc., Arcturus Therapeutics, eFFECTOR Therapeutics, Inc., Ziphius Therapeutics NV, Ionis Pharmaceuticals, Inc., Skyhawk Therapeutics, Inc., Stemirna Therapeutics Co., Ltd., RNAimmune (Sirnaomics), miRagen Therapeutics, Inc., Strand Therapeutics Inc., Nutcracker Therapeutics. Accurna Inc., Amgen Inc., Argos Therapeutics Inc., Arrowhead Pharmaceuticals. Athersys, Biocad, Boehringer Ingelheim, Cansinobio. Cartesian Therapeutics Inc, Chimeron Bio, Crispr Therapeutics Inc., Daiichi Sankyo, Eli Lilly And Co., Elixirgen Therapeutics Inc., Genentech (Subsidiary Of Roche), Greenlight Biosciences Inc., HDT Bio Corp., Intellia Therapeutics, Maxcyte Inc., Merck Kgaa, Mercurna, Novartis, Phion Therapeutics, Poseida Therapeutics Inc., Recode Therapeutics, Regulus Therapeutics, Sangamo Therapeutics Inc, Sanofi, Sarepta Therapeutics, Shanghai Bendao Gene Technology Co., Ltd., Vertex Pharmaceutical.
Key manufacturers in this field focus on offering high-quality services to clients. Also, strategies such as collaborations, partnerships, mergers, and acquisitions help boost their manufacturing capacities.
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Some of the key developments in the global market are as follow:
• In Feb 2022, Moderna launched early-stage clinical trials of an HIV mRNA vaccine. Earlier, IAVI and Moderna announced that the first doses have been administered in a clinical trial of experimental HIV vaccine antigens. The Phase I trial, IAVI G002, is designed to test the hypothesis that sequential administration of priming and boosting HIV immunogens delivered by messenger RNA (mRNA) can induce specific classes of B-cell responses and guide their early maturation toward broadly neutralizing antibody (bnAb) development.
• In Feb 2022, eTheRNA immunotherapies NV announced a strategic partnership with Merck KGaA. The partnership investigates the application of eTheRNA's proprietary mRNA design expertise and LNP-delivery platforms to disease areas selected by Merck KGaA, Darmstadt, Germany. With this collaboration, eTheRNA and Merck KGaA, Darmstadt, Germany, assess the feasibility of using eTheRNA's mRNA and LNP technologies to develop therapeutic vaccination approaches in disease models.
• In Oct 2021, Vertex Pharmaceuticals Inc. announced a partnership with a California startup to develop therapies for two genetic diseases. Vertex has developed cystic fibrosis therapies and is working with other partners on CRISPR-Cas9 systems and messenger RNA, or mRNA, therapies with Moderna Inc.
Market Segments
Global mRNA Manufacturing and Synthesis Services Market Revenue by Application (Value US$ Mn) Forecast 2022-2031
• Therapeutics and Vaccine Developers
• CDMO Organizations
• Custom Synthesis/Other Service Providers
Global mRNA Manufacturing and Synthesis Services Market Revenue by Application (Value US$ Mn) Forecast 2022-2031
• Infectious Disease Vaccines
• Other Vaccines
• Therapeutics and Others
Global mRNA Manufacturing and Synthesis Services Market Revenue by Scale of Operation (Value US$ Mn) Forecast 2022-2031
• Research / Preclinical
• Clinical
• Commercial
Global mRNA Manufacturing and Synthesis Services Market Revenue by Product (Value US$ Mn) Forecast 2022-2031
• API
• Drug Products
North America mRNA Manufacturing and Synthesis Services Market Revenue (US$ Million) By Country, 2022 To 2031
• U.S.
• Canada
Europe mRNA Manufacturing and Synthesis Services Market Revenue (US$ Million) By Country, 2022 To 2031
• Germany
• France
• Spain
• Italy
• Russia
• Rest of Europe
Asia Pacific mRNA Manufacturing and Synthesis Services Market Revenue (US$ Million) By Country, 2022 To 2031
• India
• Australia
• South Korea
• China
• Japan
• Rest of Asia Pacific
Latin America mRNA Manufacturing and Synthesis Services Market Revenue (US$ Million) By Country, 2022 To 2031
• Brazil
• Argentina
• Mexico
• Rest of Latin America
Middle East & Africa mRNA Manufacturing and Synthesis Services Market Revenue (US$ Million) By Country, 2022 To 2031
• South Africa
• GCC Countries
• Rest of Middle East & Africa
Why should buy this report:
> To receive a comprehensive industry insights of the prospects for the global mRNA Manufacturing and Synthesis services market
> To receive industry overview and future trends in global mRNA Manufacturing and Synthesis services market
> To analyze the mRNA Manufacturing and Synthesis services market drivers and challenges
> To get information on the mRNA Manufacturing and Synthesis services market size value (US$ Mn) forecast to 2030
> Significant Investments, Mergers & Acquisition in global mRNA Manufacturing and Synthesis services market industry
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Other Related Reports Published by InsightAce Analytic:
Global COVID-19 Therapeutics Market
Global mRNA Treatment Market
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