Rising Number of Cancer Patients Expands Scope for Global NSCLC Market

Non-small cell lung cancer (NSCLC) has been identified as the most common type of epithelial lung cancer. Adenocarcinomas, squamous cell carcinomas, and large cell carcinomas are the major types of NSCLC. Unlike small cell lung cancer (SCLC), NSCLC exhibits low receptivity to chemotherapy, owing to which, the need for NSCLC therapeutics has been persistently escalating in the global arena.

In this research report, the global NSCLC market therapeutics has been evaluated on the basis of the drug class, the pipeline stage, and the regional spread of this market. Based on the drug class, the market has been classified into angiogenesis inhibitor, kinase inhibitor, epidermal growth factor receptor blocker, microtubule stabilizer, PD-1/PD-L1 Inhibitor, and folate antimetabolites.

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In 2014, angiogenesis inhibitor was the most demanded drug class in the global arena. The high efficiency of this drug class fueled its demand in the U.S., Japan, Europe, and other major regions.

Avastin and Cyramza are the two main angiogenesis inhibitors available in this market. Analysts expect this segment to expand at a CAGR of 1.80% during the forecast period and increase from a value of US$1.6 bn in 2014 to US$2 bn by the end of the forecast period.

Based on the pipeline stage, NSCLC therapeutics has been categorized into early-stage (phase 1 and phase 2) pipeline drugs and late-stage (phase 3) pipeline drugs. MEDI4736 (AstraZeneca), Avelumab (Pfizer Inc.), Abemaciclib (Eli Lilly and Co.), and MPDL3280A (Roche) are the major late-stage pipeline drugs.

Regionally, the study segments the global market for NSCLC therapeutics into Asia Pacific, Europe, North America, and the Rest of the World. North America led the overall market in 2014 and was closely followed by Asia Pacific. However, Asia Pacific is anticipated to register the fastest growth rate over the forecast period.

The presence of state-of-art healthcare infrastructure and existence of a favorable reimbursement scenario are the key factors that drove the North America NSCLC therapeutics market. Besides, the growing awareness about NSCLC and the increasing implementation of government initiative to curb lung cancer are likely to boost the Asia Pacific market for NSCLC therapeutics in the coming years, notes the study.

AstraZeneca Plc, GlaxoSmithKline Plc, Genentech Inc., Eli Lilly & Co., Boehringer Ingelheim, Pfizer Inc., Celgene Corp., Roche Holding AG, Sun Pharmaceutical Industries Ltd., and Bristol-Myers Squibb are some of the leading players in the global NSCLC therapeutics market, states the research report.

The global NSCLC market is segmented into:

By Drug Class

Angiogenesis Inhibitor
-Avastin (bevacizumab)
-Cyramza (Ramucirumab)

Epidermal Growth Factor Receptor Blocker
-Tarceva (erlotinib)
-Gilotrif (afatinib)
-Iressa (gefitinib)

Kinase Inhibitor
-Xalkori (crizotinib)
-Zykadia (ceritinib)

Microtubule Stabilizer
-Abraxane (paclitaxel protein bound)
-Docetaxel

Folate Antimetabolites
-Alimta (pemetrexed)

PD-1/ PD-L1 Inhibitor
-Opdivo (nivolumab)
-Keytruda (pembrolizumab)

By Pipeline

Early-Stage (Phase I and II)
Late-Stage (Phase III)
-Avelumab Pfizer Inc.)
-MPDL3280A (Roche)
-MEDI4736 (AstraZeneca)
-Abemaciclib (Eli Lilly and Co.)
-Others

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