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Huntington's Disease Pipeline, Clinical Trials Studies, Emerging Drugs, Agreements & Collaborations, and Latest News 2023 (Updated)

10-25-2023 11:42 AM CET | Health & Medicine

Press release from: DelveInsight Business Research LLP

Huntington's Disease Pipeline

Huntington's Disease Pipeline

DelveInsight's, "Huntington's Disease Pipeline Insight 2023" report provides comprehensive insights about 50+ companies and 50+ pipeline drugs in Huntington's Disease pipeline landscape. It covers the Huntington's Disease pipeline drug profiles, including clinical and nonclinical stage products. It also covers the Huntington's Disease pipeline therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Key Takeaways from the Huntington's Disease Pipeline Report
• DelveInsight's Huntington's Disease pipeline report depicts a robust space with 50+ active players working to develop 50+ pipeline therapies for Huntington's Disease treatment.
• The leading companies working in the Huntington's Disease Market include Prilenia Therapeutics, Ionis Pharmaceuticals, Annexon, Vaccinex, Neurocrine Biosciences, EIP Pharma, SAGE Therapeutics, Celon Pharma, PTC Therapeutics, WaVe life Sciences, Amsterdam Molecular Therapeutics, Novartis, Retrotope, Hope Biosciences, Stealth BioTherapeutics, Luye Pharma Group, Neurimmune Therapeutics, SOLA Biosciences, and others.
• Promising Huntington's Disease Pipeline Therapies in the various stages of development include Dimebon, Pridopidine, SAGE-718, Tominersen 60 mg, ISIS 443139 10 mg, ER2001 injection, and others.
• October 2023: Novartis Pharmaceuticals announced a study of Phase 2 clinical trials for Branaplam. This is the first study of branaplam in adults with Huntington's Disease (HD) to determine the correct dose required to lower mutant huntingtin protein (mHTT) levels in the cerebrospinal fluid (CSF) to a degree expected to be efficacious over longer periods of time. This study is a randomized, double-blind, placebo-controlled study which will be conducted in approximately 75 early manifest HD participants. After screening and baseline assessments are completed, participants will enter the Core Treatment Period which is double-blinded and placebo-controlled.
• October 2023: UniQure Biopharma B.V. announced a study of Phase 1 clinical trials for intra-striatal rAAV5-miHTT and Imitation (sham) surgery. This is the first study of AMT-130 in patients with early manifest HD and is designed to establish safety and proof-of-concept (PoC). CT-AMT-130-01 is a Phase I/II, randomized, multicenter, multiple dose, double-blind, imitation surgery, first-in-human (FIH) study. Cohort 3 participants will receive either high or low dose (1:1 randomization).
• October 2023: Sage Therapeutics announced a study of Phase 2 clinical trials for SAGE-718. The primary purpose of this study is to assess the magnitude of the baseline difference between participants with early Huntington's Disease (HD) and healthy participants (HP) with respect to measures of cognitive performance. A 28-Day Randomized, Placebo-Controlled, Double-Blind, Parallel Groups and Normative Comparison Study to Evaluate the Effect of SAGE-718 on Functioning Capacity in Participants With Huntington's Disease.
• October 2023: Neurocrine Biosciences announced a study of Phase 3 clinical trials for Valbenazine. This is a Phase 3, randomized, double-blind, placebo-controlled study to evaluate the efficacy, safety, and tolerability of valbenazine to treat chorea in participants with Huntington disease. A Phase 3, Randomized, Double-Blind, Placebo-Controlled Study to Assess the Efficacy, Safety, and Tolerability of Valbenazine for the Treatment of Chorea Associated With Huntington Disease.
• September 2023: Hoffmann-La Roche announced a study of Phase 2 clinical trials for Tominersen 60 mg. This study will evaluate the safety, biomarkers, and efficacy of tominersen compared with placebo in participants with prodromal and early manifest Huntington's Disease. A Phase II, Randomized, Double-Blind, Placebo-Controlled, Dose-Finding Study to Evaluate the Safety, Biomarkers, and Efficacy of Tominersen in Individuals With Prodromal and Early Manifest Huntington's Disease.

Request a sample and discover the recent advances in Huntington's Disease Treatment Drugs @ Huntington's Disease Pipeline Report- https://www.delveinsight.com/report-store/huntingtons-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

In the Huntington's Disease pipeline report, detailed description of the drug is given which includes mechanism of action of the drug, clinical studies, Huntington's Disease NDA approvals (if any), and product development activities comprising the technology, Huntington's Disease collaborations, licensing, mergers and acquisition, funding, designations and other product related details.

Huntington's Disease Overview
Huntington's disease is a rare, inherited disease that causes the progressive breakdown (degeneration) of nerve cells in the brain. It is an autosomal dominant disorder caused by a single defective gene on chromosome 4. The symptoms of Huntington's Disease include involuntary jerking or writhing movements (chorea), muscle problems, such as rigidity or muscle contracture (dystonia), slow or abnormal eye movements, impaired balance, difficulty with speech or swallowing, difficulty organizing, prioritizing or focusing on tasks, and/or fatigue and loss of energy.

Find out more about Huntington's Disease Therapeutics Assessment @ Huntington's Disease Preclinical and Discovery Stage Products- https://www.delveinsight.com/sample-request/huntingtons-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Huntington's Disease Emerging Drugs Profile
• Pridopidine: Prilenia Therapeutics
• Tominersen: Ionis Pharmaceuticals

Huntington's Disease Pipeline Therapeutics Assessment
There are approx. 50+ key companies which are developing the Huntington's Disease therapies. The Huntington's Disease companies which have their Huntington's Disease drug candidates in the most advanced stage, i.e. Phase III include, Ionis Pharmaceuticals.

DelveInsight's Huntington's Disease Pipeline report covers around 50+ products under different phases of clinical development like
• Late stage products (Phase III)
• Mid-stage products (Phase II)
• Early-stage product (Phase I) along with the details of
• Pre-clinical and Discovery stage candidates
• Discontinued & Inactive candidates

Huntington's Disease Pipeline Report provides the therapeutic assessment of the pipeline drugs by the Route of Administration. Products have been categorized under various ROAs such as
• Oral
• Parenteral
• Intravitreal
• Subretinal
• Topical

Huntington's Disease Pipeline Products have been categorized under various Molecule types such as
• Monoclonal Antibody
• Peptides
• Polymer
• Small molecule
• Gene therapy

Dive deep into rich insights for new drugs for Huntington's Disease Treatment, Visit @ Huntington's Disease Market Drivers and Barriers, and Future Perspective- https://www.delveinsight.com/sample-request/huntingtons-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Scope of the Huntington's Disease Pipeline Report
• Coverage- Global
• Huntington's Disease Therapeutic Assessment by Product Type: Mono, Combination, Mono/Combination
• Huntington's Disease Therapeutic Assessment by Clinical Stages: Discovery, Pre-clinical, Phase I, Phase II, Phase III
• Huntington's Disease Companies- Prilenia Therapeutics, Ionis Pharmaceuticals, Annexon, Vaccinex, Neurocrine Biosciences, EIP Pharma, SAGE Therapeutics, Celon Pharma, PTC Therapeutics, WaVe life Sciences, Amsterdam Molecular Therapeutics, Novartis, Retrotope, Hope Biosciences, Stealth BioTherapeutics, Luye Pharma Group, Neurimmune Therapeutics, SOLA Biosciences, and others.
• Huntington's Disease Pipeline Therapies- Dimebon, Pridopidine, SAGE-718, Tominersen 60 mg, ISIS 443139 10 mg, ER2001 injection, and others.

Dive deep into rich insights for new drugs for Huntington's Disease Treatment, Visit @ Huntington's Disease Market Drivers and Barriers, and Future Perspective- https://www.delveinsight.com/sample-request/huntingtons-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of Content
1. Introduction
2. Executive Summary
3. Huntington's Disease: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Huntington's Disease - DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. Pridopidine: Prilenia Therapeutics
9. Drug profiles in the detailed report…..
10. Mid Stage Products (Phase II)
11. Drug Name: Company Name
12. Drug profiles in the detailed report…..
13. Early Stage Products (Phase I)
14. Drug Name: Company Name
15. Drug profiles in the detailed report…..
16. Preclinical/Discovery Stage Products
17. Drug Name: Company Name
18. Drug profiles in the detailed report…..
19. Inactive Products
20. Huntington's Disease Key Companies
21. Huntington's Disease Key Products
22. Huntington's Disease- Unmet Needs
23. Huntington's Disease- Market Drivers and Barriers
24. Huntington's Disease- Future Perspectives and Conclusion
25. Huntington's Disease Analyst Views
26. Appendix

For further information on the Huntington's Disease Pipeline therapeutics, reach out to Huntington's Disease Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/huntingtons-disease-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

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About Us

DelveInsight is a leading healthcare-focused market research and consulting firm that provides clients with high-quality market intelligence and analysis to support informed business decisions. With a team of experienced industry experts and a deep understanding of the life sciences and healthcare sectors, we offer customized research solutions and insights to clients across the globe. Connect with us to get high-quality, accurate, and real-time intelligence to stay ahead of the growth curve.

Company Name: DelveInsight Business Research LLP
Contact Person: Yash Bhardwaj
Email: ybhardwaj@delveinsight.com
Phone: 9193216187
Address: 304 S. Jones Blvd #2432
City: Las Vegas
State: NV
Country: United States
Website: https://www.delveinsight.com/consulting/ci-tracking

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