Global Fragment-Based Drug Discovery Market Outlook 2031

𝗚𝗹𝗼𝗯𝗮𝗹 𝗙𝗿𝗮𝗴𝗺𝗲𝗻𝘁-𝗕𝗮𝘀𝗲𝗱 𝗗𝗿𝘂𝗴 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆 𝗠𝗮𝗿𝗸𝗲𝘁 𝗢𝘂𝘁𝗹𝗼𝗼𝗸 𝟮𝟬𝟯𝟭

The global fragment-based drug discovery (FBDD) market is poised for remarkable growth, with a projected compound annual growth rate (CAGR) of 11.5% from 2023 to 2031. This innovative approach to early-stage drug development has gained substantial attention due to its ability to revolutionize the way we discover and develop new therapeutic agents. In 2022, the FBDD market was valued at US$ 795.4 million, and this value is expected to surge to over US$ 2.1 billion by the end of 2031.

𝗥𝗲𝗾𝘂𝗲𝘀𝘁 𝗳𝗼𝗿 𝗮 𝘀𝗮𝗺𝗽𝗹𝗲 𝗼𝗳 𝘁𝗵𝗶𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗿𝗲𝗽𝗼𝗿𝘁 𝗮𝘁 (𝗨𝘀𝗲 𝗖𝗼𝗿𝗽𝗼𝗿𝗮𝘁𝗲 𝗠𝗮𝗶𝗹 𝗜𝗱 𝗳𝗼𝗿 𝗤𝘂𝗶𝗰𝗸 𝗥𝗲𝘀𝗽𝗼𝗻𝘀𝗲) -

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𝗔𝗱𝘃𝗮𝗻𝘁𝗮𝗴𝗲𝘀 𝗼𝗳 𝗙𝗕𝗗𝗗: 𝗛𝗶𝗴𝗵 𝗛𝗶𝘁 𝗥𝗮𝘁𝗲𝘀 𝗮𝗻𝗱 𝗘𝗻𝗵𝗮𝗻𝗰𝗲𝗱 𝗖𝗵𝗲𝗺𝗶𝗰𝗮𝗹 𝗗𝗶𝘃𝗲𝗿𝘀𝗶𝘁𝘆

Fragment-based drug discovery has become a powerful tool in the pharmaceutical industry due to its unique advantages. Unlike traditional high-throughput screening methods, FBDD involves testing small, low molecular weight fragments as starting points for drug development. This approach offers several benefits, including increased chemical diversity, higher hit rates, and the ability to target challenging proteins that were once considered difficult to address.

The higher hit rates associated with FBDD are attributed to its screening strategy. By focusing on simple chemical structures in the form of small fragments, FBDD increases the likelihood of interactions with target proteins. As a result, more potential lead compounds are identified, streamlining the drug discovery process.

𝗔𝗽𝗽𝗹𝗶𝗰𝗮𝘁𝗶𝗼𝗻 𝗶𝗻 𝗧𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰 𝗔𝗿𝗲𝗮𝘀: 𝗔𝗱𝗱𝗿𝗲𝘀𝘀𝗶𝗻𝗴 𝗖𝗼𝗺𝗽𝗹𝗲𝘅 𝗗𝗶𝘀𝗲𝗮𝘀𝗲𝘀

One of the standout features of FBDD is its versatility across various therapeutic areas. In the field of oncology, for instance, FBDD has demonstrated immense potential in targeting specific cancer-associated proteins. Researchers have utilized this approach to identify small molecule fragments that bind to oncogenic proteins involved in tumor growth.

Furthermore, FBDD's success extends to the central nervous system (CNS) disorders. Leading biotech companies have applied FBDD to target proteins associated with neurodegenerative diseases like Alzheimer's and Parkinson's. By leveraging FBDD's capabilities, they aim to develop innovative therapies for these challenging conditions.

𝗕𝘂𝘆 𝘁𝗵𝗶𝘀 𝗣𝗿𝗲𝗺𝗶𝘂𝗺 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗥𝗲𝗽𝗼𝗿𝘁 | 𝗜𝗺𝗺𝗲𝗱𝗶𝗮𝘁𝗲 𝗗𝗲𝗹𝗶𝘃𝗲𝗿𝘆 𝗔𝘃𝗮𝗶𝗹𝗮𝗯𝗹𝗲 𝗮𝘁 -

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𝗘𝗳𝗳𝗶𝗰𝗶𝗲𝗻𝗰𝘆 𝗮𝗻𝗱 𝗦𝗽𝗲𝗲𝗱 𝗶𝗻 𝗗𝗿𝘂𝗴 𝗗𝗶𝘀𝗰𝗼𝘃𝗲𝗿𝘆

The fragment screening segment is a major driver of the FBDD market, as it offers both efficiency and speed in the drug discovery process. This segment includes services such as library screening, biophysical screening (NMR, X-ray crystallography), and computational screening.

Fragment screening enables exploration of a vast chemical space using small fragments that can access unique binding sites on target proteins. This not only leads to the discovery of novel binding modes but also provides crucial insights into atomic-level interactions, guiding the optimization process effectively. Moreover, screening smaller libraries of fragments is faster and more cost-effective than traditional high-throughput screening, resulting in a more streamlined drug discovery journey.

𝗥𝗶𝘀𝗲 𝗶𝗻 𝗗𝗲𝗺𝗮𝗻𝗱 𝗳𝗼𝗿 𝗛𝗶𝗴𝗵 𝗦𝗽𝗲𝗰𝗶𝗳𝗶𝗰𝗶𝘁𝘆 & 𝗦𝗲𝗻𝘀𝗶𝘁𝗶𝘃𝗶𝘁𝘆 𝗶𝗻 𝗖𝗮𝗻𝗰𝗲𝗿 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 & 𝗗𝗿𝘂𝗴 𝗗𝗲𝘃𝗲𝗹𝗼𝗽𝗺𝗲𝗻𝘁

In terms of application, oncology is expected to dominate the FBDD market during the forecast period. This is primarily due to the increasing focus on cancer research and drug development. Prominent pharmaceutical companies are investing heavily in oncology-focused FBDD research and forming collaborations with specialized FBDD providers to identify novel drug candidates for various oncology targets.

𝗥𝗲𝗾𝘂𝗲𝘀𝘁 𝗳𝗼𝗿 𝗰𝘂𝘀𝘁𝗼𝗺𝗶𝘇𝗮𝘁𝗶𝗼𝗻 𝗼𝗳 𝘁𝗵𝗶𝘀 𝗿𝗲𝘀𝗲𝗮𝗿𝗰𝗵 𝗿𝗲𝗽𝗼𝗿𝘁 𝗮𝘁 -

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𝗚𝗹𝗼𝗯𝗮𝗹 𝗟𝗲𝗮𝗱𝗲𝗿𝘀 𝗮𝗻𝗱 𝗜𝗻𝗻𝗼𝘃𝗮𝘁𝗼𝗿𝘀 𝗶𝗻 𝗙𝗕𝗗𝗗

Key players in the FBDD market are making significant investments in research and development, as well as collaborative efforts, to enhance their market presence. Companies such as Alveus Pharmaceuticals Pvt. Ltd., Astex Pharmaceuticals, Charles River Laboratories International, Inc., and Evotec AG are at the forefront of FBDD innovation. These players have demonstrated their commitment to advancing drug discovery by leveraging FBDD's unique advantages.

𝗥𝗲𝗴𝗶𝗼𝗻𝗮𝗹 𝗗𝘆𝗻𝗮𝗺𝗶𝗰𝘀

North America remains a dominant force in the FBDD market, driven by substantial investments in research and development, well-established infrastructure, and robust healthcare systems. The region's proactive adoption of technological advancements positions it as a leader in implementing FBDD techniques.

Asia Pacific is witnessing a surge in demand for FBDD services, driven by increased investment in healthcare infrastructure and a strong emphasis on quality management. Countries such as China and Japan are emerging as potential markets for FBDD, signaling a growing interest in innovative drug discovery approaches.

𝗠𝗼𝗿𝗲 𝗧𝗿𝗲𝗻𝗱𝗶𝗻𝗴 𝗥𝗲𝗽𝗼𝗿𝘁𝘀 𝗯𝘆 𝗧𝗿𝗮𝗻𝘀𝗽𝗮𝗿𝗲𝗻𝗰𝘆 𝗠𝗮𝗿𝗸𝗲𝘁 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵 -

Congestive Heart Failure Drugs Market

https://www.globenewswire.com/en/news-release/2023/04/13/2646759/0/en/Congestive-Heart-Failure-Drugs-Market-Size-to-Cross-USD-13-5-Bn-Revenue-by-2031-TMR-Study.html

Cardiotonic Agents Market

https://www.globenewswire.com/en/news-release/2023/04/03/2639893/0/en/Cardiotonic-Agents-Market-Size-to-Reach-USD-4-5-Bn-by-2031-Due-to-the-Rise-in-Prevalence-of-Cardiovascular-Diseases-TMR-Study.html

𝗔𝗯𝗼𝘂𝘁 𝗨𝘀 𝗧𝗿𝗮𝗻𝘀𝗽𝗮𝗿𝗲𝗻𝗰𝘆 𝗠𝗮𝗿𝗸𝗲𝘁 𝗥𝗲𝘀𝗲𝗮𝗿𝗰𝗵

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𝗖𝗼𝗻𝘁𝗮𝗰𝘁 𝗨𝘀

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