Press release
Global NMDA Receptor Antagonist Market Research Report 2023 to 2028
NMDA receptor antagonists are a class of drugs that block the activity of the N-methyl-D-aspartate (NMDA) receptor, which is involved in excitatory neurotransmission in the brain. While NMDA receptor antagonists have primarily been studied and used in conditions like depression and schizophrenia, there is emerging research exploring their potential in Parkinson's disease and Alzheimer's disease. However, it's important to note that the use of NMDA receptor antagonists in these conditions is still investigational, and no specific drugs in this class have been approved for the treatment of Parkinson's disease or Alzheimer's disease.
In Parkinson's disease, research suggests that NMDA receptor antagonists may have neuroprotective effects and potentially reduce the motor symptoms associated with the condition. The excessive activation of NMDA receptors can lead to an influx of calcium ions and subsequent neuronal damage, which is believed to contribute to the progression of Parkinson's disease. By blocking NMDA receptors, antagonists may help regulate the calcium influx and provide neuroprotection. However, more research is needed to determine the effectiveness and safety of NMDA receptor antagonists in Parkinson's disease.
In Alzheimer's disease, the role of NMDA receptor antagonists is more complex. Alzheimer's disease involves the accumulation of beta-amyloid plaques and the formation of neurofibrillary tangles, which lead to neuronal dysfunction and cognitive decline. NMDA receptor antagonists may help by modulating glutamate activity, as excessive glutamate release can be toxic to neurons and contribute to neurodegeneration. By blocking NMDA receptors, antagonists can potentially reduce the excitotoxicity associated with Alzheimer's disease. However, clinical trials investigating NMDA receptor antagonists in Alzheimer's disease have shown mixed results, and more research is necessary to determine their efficacy.
It's important to recognize that the treatment of Parkinson's disease and Alzheimer's disease is complex and multifaceted. Current standard therapies involve a combination of medications, rehabilitation strategies, and supportive care.
Market Share Analysis
The North American market for NMDA Receptor Antagonist is estimated to increase from $ million in 2022 to reach $ million by 2028, at a CAGR of % during the forecast period of 2023 through 2028.
Asia-Pacific market for NMDA Receptor Antagonist is estimated to increase from $ million in 2022 to reach $ million by 2028, at a CAGR of % during the forecast period of 2022 through 2028.
The major global manufacturers of NMDA Receptor Antagonist include Algernon Pharmaceuticals, Relmada Therapeutics, UCB, Avanir Pharmaceuticals, Axsome Therapeutics, Seelos Therapeutics, PharmaTher, Cessatech and ATAI Life Sciences, etc. In 2021, the world's top three vendors accounted for approximately % of the revenue.
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NMDA Receptor Antagonist segment by Type
• Vaccine
• Monoclonal Antibody
• Application Insights
NMDA Receptor Antagonist segment by Application
• Parkinson's Disease
• Alzheimer's Disease
• Others
BY REGION
• North America
• Europe
• Asia-Pacific
• Latin America
• Middle East & Africa
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