What is the estimated growth rate (CAGR) of the global tangential flow filtration market?

Tangential Flow Filtration Market in terms of revenue was estimated to be worth $1.9 billion in 2023 and is poised to reach $3.6 billion by 2028, growing at a CAGR of 13.5% from 2023 to 2028 according to a new report by MarketsandMarkets™. The TFF market is expected to have a growth rate of 13.5% during 2023-2028. Increasing benefits over normal flow filtration, the introduction of single-use technologies, adoption of gamp guidelines, increasing investment by pharmaceutical companies, growing biopharmaceutical industries are some of the factors that will accelerate the growth of the Tangential Flow Filtration Market in the forecast period.

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In 2022, the systems segment accounted for the largest share of the product segment in the Tangential Flow filtration market.

On the basis of products, the tangential flow filtration market is segmented into systems, membrane filters, and other tff products. In 2022, the systems segment accounted for the largest share of the market and is expected to grow at the highest CAGR during 2023-2028. Tangential filtration systems consist of automated and mechanical filtration systems. These systems provide maximum operational reliability. Some of the benefits associated with these systems include a high retention rate, less consumption of energy, low cost, and reduced cross-contamination risk. With the help of such systems, pharmaceutical companies can achieve the highest quality products. The systems segment is further segmented into single-use and reusable systems. Single-use systems are gaining importance in separation and purification applications. Developments in research techniques and increased demand for more specificity in the filtration process are increasing the adoption of single-use technologies in many small-scale biopharmaceutical processes.

In 2022, the microfiltration segment accounted for the largest share of the technique segment in the Tangential Flow filtration market.

On the basis of technique, the tangential flow filtration market is segmented into microfiltration, ultrafiltration, nanofiltration, and other techniques. In 2022, the microfiltration segment accounted for the largest market share. The filters used in this technique can be in a submerged configuration or a pressure vessel configuration; they can be hollow fibers, flat, sheet, tubular, or spiral. Membrane filtration technique can be used for removing suspended matter (>99%), harmful microorganisms (e.g., bacteria, protozoa, algae, and fungi) (>99%), and PAHs. Also, MF can be implemented to break down emulsions. Microfiltration with hollow-fiber filters finds applications in processes such as clarification, purification of cell broths, separation of cell debris, and separation of macromolecules. This technique is also used for harvesting cells in upstream bioprocessing and for the recovery & purification of biomass during the production of antibiotics. In biotechnology, microfiltration is used for the retention of biomass from fermentation broths. This technique is also used for the removal of natural and synthetic organic matter to reduce the fouling potential.

In 2022, the Asia Pacific region is the fastest-growing region of the Tangential Flow filtration market.

The tangential flow filtration market is divided into five regions including, North America, Europe, Asia Pacific, Latin America and Middle East and Africa. The Asia Pacific market is expected to register the highest CAGR during 2023-2028. Factors responsiblr for the growth includes, unique industry dynamics accompanied by a highly competitive landscape owing to its complex and diverse regulatory landscape and varying pharma industry infrastructures across each country, impacting innovation in each country.

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Tangential Flow Filtration Market Dynamics:

Drivers:

Growing advantages of tangential flow filtration over normal flow filtration
Rising R&D spending in pharmaceutical & biotechnology industries
Increasing adoption of single-use technologies
Increased adoption of Good Automated Manufacturing Practice (GAMP)

Restraints:

High capital investments for new production facilities to limit the entry of small players
Opportunities:

Emerging economies offer lucrative growth opportunities
Rising therapeutic applications of recombinant proteins

Challenges:

Increased complexities introduced by the interaction of charged excipients and proteins to restrict the market growth
Difficulty in the survival of small players and new entrants

Key Market Players:

Key players in the Market include Merck KGaA (Germany), Danaher Corporation (US), Sartorius AG (Germany), Parker Hannifin Corporation (US), Repligen Corporation (US), Alfa Laval Corporate AB (Sweden), ANDRITZ (Austria), Meissner Filtration Products, Inc. (US), Cole-Parmer Instrument Company, LLC (US), Solaris Biotechnology Srl (Italy), Koch Separation Solutions (US), Sterlitech Corporation US), Synder Filtration, Inc. (US), PendoTECH (US), ARTeSYN Biosolutions (Ireland), Microfilt India Pvt. Ltd. (India), Bionet (Spain), SYSBIOTECH GmbH (Austria), Cobetter Filtration Equipment Co., Ltd. (China), Biotree (India), FORMULATRIX (US), Mantec Technical Ceramics Ltd. (UK), Smartflow Technologies (US), TAMI Industries (France), and SPF Technologies LLC (US).

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