Press release
Focal Segmental Glomerulosclerosis (FSGS) Pipeline Report 2023: FDA, EMA and PDMA Approvals, Therapies, Clinical Trials, and Treatment Outlook | Companies- Travere Therapeutics, Dimerix, Goldfinch Bio, Vertex Pharmaceuticals, Pfizer, Chinook Therapeutics,
Focal Segmental Glomerulosclerosis (FSGS) Pipeline
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Focal Segmental Glomerulosclerosis Overview
Focal Segmental Glomerulosclerosis (FSGS) is a well-defined histologic pattern of injury characterized by sclerosis, hyalinosis, foam-cell infiltration, vacuolization of podocytes, and podocyte precursor proliferation between glomeruli tuft and Bowman's capsule. It is "focal" in that only some glomeruli are affected and "segmental" where only a portion of the affected glomerulus is sclerosed. It typically presents with nephrotic syndrome with characterized proteinuria and obliteration or failure of glomerular capillary loops by increased extracellular matrix in glomeruli capillary tufts. However, the capillary injury does not occupy the entire glomerulus.
Some of the key companies in the Focal Segmental Glomerulosclerosis (FSGS) Market include:
• Travere Therapeutics
• Dimerix
• Goldfinch Bio
• Vertex Pharmaceuticals
• Pfizer
• Chinook Therapeutics, Inc.
• Genentech
• Complexa
• Imara
• ZyVersa
• Boehringer Ingelheim
• Eli Lilly and Company
• And many others.
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Focal Segmental Glomerulosclerosis Pipeline Analysis
The report provides insights into:
• The report provides detailed insights about companies that are developing therapies for the treatment of Focal Segmental Glomerulosclerosis with aggregate therapies developed by each company for the same.
• It accesses the Different therapeutic candidates segmented into early-stage, mid-stage, and late-stage of development for the Focal Segmental Glomerulosclerosis Treatment.
• Focal Segmental Glomerulosclerosis key companies involved in targeted therapeutics development with respective active and inactive (dormant or discontinued) projects.
• Focal Segmental Glomerulosclerosis Drugs under development based on the stage of development, route of administration, target receptor, monotherapy or combination therapy, a different mechanism of action, and molecular type.
• Detailed analysis of collaborations (company-company collaborations and company-academia collaborations), licensing agreement, and financing details for future advancement of the Focal Segmental Glomerulosclerosis market.
@ https://www.delveinsight.com/sample-request/focal-segmental-glomerulosclerosis-fsgs-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=apr
Emerging Focal Segmental Glomerulosclerosis Drugs
DMX-200: Dimerix Bioscience
DMX-200 is a chemokine receptor (CCR2) blocker and is administered to patients taking an angiotensin II type I (AT1) receptor blocker (ARB), which is the standard of care treatment for focal segmental glomerulosclerosis. DMX-200 has been granted patents in various territories until 2032 and has also been granted Orphan Drug Designation by the FDA and EMA.
Sparsentan: Travere Therapeutics
Sparsentan, a Dual Endothelin Angiotensin Receptor Antagonist (DEARA), is a novel investigational product candidate selectively targeting the endothelin A receptor (ETAR) and the angiotensin II subtype 1 receptor (AT1R). Pre-clinical data have shown that blockade of both endothelin type A and angiotensin II type 1 pathways in forms of rare chronic kidney disease reduces proteinuria, protects podocytes, and prevents glomerulosclerosis and mesangial cell proliferation. The US Food and Drug Administration (FDA) and European Medicines Agency (EMA) have granted sparsentan orphan drug designation for FSGS. Currently, Sparsentan is in Phase III development for the treatment of focal segmental glomerulosclerosis (FSGS).
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Focal Segmental Glomerulosclerosis Therapeutics Landscape
The available therapeutics treatment options in the Focal Segmental Glomerulosclerosis (FSGS) landscape aims to reduce complications and protect from further kidney damage. Few companies are performing clinical trials to develop cell therapies and receptor modulators for the treatment of FSGS.
Focal Segmental Glomerulosclerosis (FSGS) Therapies covered in the report include:
• Sparsentan
• Voclosporin
• DMX-200
• CXA-10
• Abatacept
• Bleselumab
• PF-06730512
• And many more.
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Table of Content
1. Report Introduction
2. Focal Segmental Glomerulosclerosis
3. Focal Segmental Glomerulosclerosis Current Treatment Patterns
4. Focal Segmental Glomerulosclerosis - DelveInsight's Analytical Perspective
5. Therapeutic Assessment
6. Focal Segmental Glomerulosclerosis Late Stage Products (Phase-III)
7. Focal Segmental Glomerulosclerosis Mid Stage Products (Phase-II)
8. Early Stage Products (Phase-I)
9. Pre-clinical Products and Discovery Stage Products
10. Inactive Products
11. Dormant Products
12. Focal Segmental Glomerulosclerosis Discontinued Products
13. Focal Segmental Glomerulosclerosis Product Profiles
14. Focal Segmental Glomerulosclerosis Key Companies
15. Focal Segmental Glomerulosclerosis Key Products
16. Dormant and Discontinued Products
17. Focal Segmental Glomerulosclerosis Unmet Needs
18. Focal Segmental Glomerulosclerosis Future Perspectives
19. Focal Segmental Glomerulosclerosis Analyst Review
20. Appendix
21. Report Methodology
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Media Contact
Company Name: DelveInsight Business Research LLP
Contact Person: Ankit Nigam
Email: info@delveinsight.com
City: Albany
State: New York
Country: United States
Website: https://www.delveinsight.com/consulting
About DelveInsight
DelveInsight is a leading Business Consultant, and Market Research Firm focused exclusively on life sciences. It supports pharma companies by providing comprehensive end-to-end solutions to improve their performance.
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