100+ Active Companies working to develop 100+ Pipeline Therapies for Eczema Treatment Landscape | Major Companies- GSK, AstraZeneca, Novartis, and Others

DelveInsight's, "Eczema- Pipeline Insight 2023" report provides comprehensive insights about 100+ companies and 100+ pipeline drugs in Eczema pipeline landscape. It covers the pipeline drug profiles, including clinical and nonclinical stage products. It also covers the therapeutics assessment by product type, stage, route of administration, and molecule type. It further highlights the inactive pipeline products in this space.

Key Takeaways from the Eczema Pipeline Report

• DelveInsight's eczema pipeline report depicts a robust space with 100+ active players working to develop 100+ pipeline therapies for eczema treatment.

• The leading Eczema companies include Kymab, BiomX, GlaxoSmithKline, Arjil Pharmaceuticals, SCM Lifescience, Sun Pharmaceutical Industries, Brickell Biotech Inc, Dermira, AstraZeneca, Kyowa Kirin, UCB Biopharma, Arcutis Biotherapeutics, Ichnos Sciences, AOBiome, Kangstem Biotech, Devonian, VYNE therapeutics, BenevolentAI, Amytrx Therapeutics, Asana BioSciences, RAPT Therapeutics, Celgene Corporation, Shaperon, Allakos, KeyMed Biosciences, Ribon Therapeutics, Pfizer, Amgen, Evelo Biosciences, Novartis Pharmaceuticals, Oneness Biotech, Aclaris Therapeutics, Biosion, LEO Pharma, Principia Biopharma, Reistone Biopharma Company Limited, Botanix Pharmaceuticals, Qurient, Eli Lilly and Company, Suzhou Connect Biopharmaceuticals, Hoth Therapeutics, Kymera Therapeutics, KoBioLabs, and others

• Promising eczema pipeline therapies include Amlitelimab, BX 005, LP 0145, GSK 1070806, AR 100, SCM AGH, SCD-044, BBI 02, Lebrikizumab, Benralizumab, UCB9741, ARQ-151, si-544, KHK-4083, ISB-830, B 244, FURESTEM-AD inj, PUR-0110, UCB-1381, FMX-114, BEN 2293, AMTX 100, Gusacitinib, RPT 193, CC 93538, HY-209, AK 002, CM 326, CM 310, RBN 3143, PF-07242813, Apremilast, EDP 1815, MEDI3506, Etrasimod, CMK 389, FB 825, ATI-1777, BSI 045B, LEO-152020, Rilzabrutinib, SHR0302, PRN-473, BTX-1204A, Q-301, Lebrikizumab, CBP 201, BioLexa, KT 474, KBL 697, and others.

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Eczema Overview
Eczema (also known as atopic dermatitis) is most typically found in children, however, it can also occur in adults. People with the illness have dry, itchy skin that is prone to infection. Eczema is widely referred to as the "itch that rashes" because of dry skin that causes a rash when scratched or rubbed. The most important eczema treatment is skin hydration, followed by topical steroids for flare-ups.

Recent Developmental Activities in the Eczema Treatment Landscape

• In August 2022, UNION therapeutics announced enrollment of the first patient in ADESOS Phase II b study of orismilast MR tablet in patients with atopic dermatitis. The purpose of the study is to identify the appropriate dose regimen for Phase III studies.

• In August 2022, Lynk Pharmaceuticals Co., announced that its innovative drug LNK01004, had been approved by National Medical Products Administration (NMPA) for clinical trials in the treatment of atopic dermatitis (AD).

• In June 2022, ASLAN Pharmaceuticals announced that it had initiated a research collaboration with Dr. Shawn Kwatra and Dr. Madan Kwatra from Duke University Medical Center to investigate the unique role of the IL-13Ra1 subunit, distinct from the role of other pathway components, in Type 2-mediated inflammatory diseases, specifically atopic dermatitis (AD).

• In May 2022, Brickell Biotech, Inc. announced that the first subjects were dosed in the single ascending dose ("SAD") portion of the Company's Phase 1 clinical trial evaluating BBI-02 in healthy adult subjects and patients with atopic dermatitis ("AD").

• In April 2022, Eli Lilly and Company announced that Lebrikizumab Combined with Topical Corticosteroids showed significant improvements in disease severity for Atopic Dermatitis. Lebrikizumab significantly improved several areas of great importance to patients with atopic dermatitis, including skin and itch, in a pivotal combination trial that met all primary and key secondary endpoints

• In February 2022, FDA accepted for priority review the supplemental biologics license application (sBLA) for dupilumab (Dupixent, Regeneron Pharmaceuticals, Sanofi) as an add-on maintenance treatment for children aged 6 months to 5 years with moderate to severe atopic dermatitis (AD).

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Eczema Emerging Drugs

• Amlitelimab: Kymab
Amlitelimab SAR445229 (formerly KY1005) is a human monoclonal antibody that targets OX40L, a key regulator of the immune system. Amlitelimab is designed to rebalance the immune system by blocking inappropriate activation and proliferation of 'pro-inflammatory' effector T cells and promoting expansion of 'anti-inflammatory' regulatory T cells, without broad suppression of the immune system. It is believed this mechanism-of-action means Amlitelimab could be applicable to a range of autoimmune and inflammatory diseases. In Phase I clinical trial in healthy volunteers, Amlitelimab was able to block T cell-driven skin inflammation while being well tolerated. It is believed the immune-modulating mechanism of Amlitelimab has broad potential therapeutic application in multiple diseases caused by immune dysregulation. Currently, the drug is being developed in the Phase II stage of clinical trial evaluation for the treatment of Eczema.

• BX 005: BiomX
BX005, a topical phage cocktail that targets Staphylococcus aureus (S. aureus), a bacteria associated with the manifestation of the disease. In preclinical in vitro studies, BX005 was shown to be active against over 90% of strains of S. aureus isolated from the skin of subjects from U.S. and Europe, including antibiotic resistant strains. Currently, the drug is being developed in the Phase I/II stage of clinical trial evaluation for the treatment of Atopic Dermatitis.

• LP 0145: LEO Pharma
LP 0145, is an anti-inflammatory monoclonal antibody under development for atopic dermatitis. Currently, the drug is being developed in the Phase II stage of clinical trial evaluation for the treatment of Eczemas.

Eczema Pipeline Therapeutic Assessment
There are approx. 100+ key companies which are developing the therapies for Eczema. The companies which have their Eczema drug candidates in the most advanced stage, i.e. phase II include, LEO Pharma.

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Scope of the Eczema Pipeline Report

• Coverage- Global

• Eczema Companies: Kymab, BiomX, GlaxoSmithKline, Arjil Pharmaceuticals, SCM Lifescience, Sun Pharmaceutical Industries, Brickell Biotech Inc, Dermira, AstraZeneca, Kyowa Kirin, UCB Biopharma, Arcutis Biotherapeutics, Ichnos Sciences, AOBiome, Kangstem Biotech, Devonian, VYNE therapeutics, BenevolentAI, Amytrx Therapeutics, Asana BioSciences, RAPT Therapeutics, Celgene Corporation, Shaperon, Allakos, KeyMed Biosciences, Ribon Therapeutics, Pfizer, Amgen, Evelo Biosciences, Novartis Pharmaceuticals, Oneness Biotech, Aclaris Therapeutics, Biosion, LEO Pharma, Principia Biopharma, Reistone Biopharma Company Limited, Botanix Pharmaceuticals, Qurient, Eli Lilly and Company, Suzhou Connect Biopharmaceuticals, Hoth Therapeutics, Kymera Therapeutics, KoBioLabs, and others.
• Eczema Pipeline Therapies: Amlitelimab, BX 005, LP 0145, GSK 1070806, AR 100, SCM AGH, SCD-044, BBI 02, Lebrikizumab, Benralizumab, UCB9741, ARQ-151, si-544, KHK-4083, ISB-830, B 244, FURESTEM-AD inj, PUR-0110, UCB-1381, FMX-114, BEN 2293, AMTX 100, Gusacitinib, RPT 193, CC 93538, HY-209, AK 002, CM 326, CM 310, RBN 3143, PF-07242813, Apremilast, EDP 1815, MEDI3506, Etrasimod, CMK 389, FB 825, ATI-1777, BSI 045B, LEO-152020, Rilzabrutinib, SHR0302, PRN-473, BTX-1204A, Q-301, Lebrikizumab, CBP 201, BioLexa, KT 474, KBL 697, and others.

• Eczema Pipeline Segmentation: Product Type, Molecule Type, Route of Administration

Dive deep into rich insights for drugs for Eczema Market Drivers and Eczema Market Barriers, click here @ Eczema Unmet Needs and Analyst Views- https://www.delveinsight.com/sample-request/eczema-pipeline-insight?utm_source=openpr&utm_medium=pressrelease&utm_campaign=ypr

Table of content
1. Introduction
2. Executive Summary
3. Eczema: Overview
4. Pipeline Therapeutics
5. Therapeutic Assessment
6. Eczema- DelveInsight's Analytical Perspective
7. Late Stage Products (Phase III)
8. Drug name : Company name
9. Mid Stage Products (Phase II)
10. Amlitelimab: Kymab
11. Early Stage Products (Phase I)
12. Drug name : Company name
13. Preclinical and Discovery Stage Products
14. Drug name: Company name
15. Inactive Products
16. Eczema Key Companies
17. Eczema Key Products
18. Eczema- Unmet Needs
19. Eczema- Market Drivers and Barriers
20. Eczema- Future Perspectives and Conclusion
21. Eczema Analyst Views
22. Eczema Key Companies
23. Appendix

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