Press release
Graft Versus Host Disease (GVHD) - Drug Pipeline Landscape, 2022 | Amcyte Pharma Inc, AnaMar AB, AnaptysBio Inc, ASC Therapeutics Inc
Graft Versus Host Disease (GVHD)
Graft Versus Host disease (GVHD) is an immune mediated systemic disorder associated with complex interaction between donor and recipient adaptive immunity. It is a common complication after hematopoietic stem cell transplant (HCT), here the graft recognizes the host as a foreign and attack the recipient's body cell. GvHD is of two types: acute GvHD - which develops within 100 days of transplantation and chronic GvHD - which develops after 100 days of transplantation.
GvHD occurs after the bone marrow transplants and stem cell transplants. Following are the other occurrences of GvHD - allogenic bone transplantation, solid organs that are rich in lymphoid cells and un-irradiated blood.
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GvHD is diagnosed through imaging - X-ray abdomen, CT scan abdomen and chest, PET scan and MRI. Other diagnosis involves liver function tests, liver biopsy and capsule endoscopy.
Treatments depends on the severity of symptoms and organs involvement. Corticosteroids are commonly used treatment. Topical steroids are used to control local symptoms. Cyclosporine is added to the treatment regimen of chronic GvHD. Prophylactic treatment is recommended.
There are many other trials ongoing in GVHD Drug Development. These trials are studying a variety of new and existing drugs, as well as new ways to use existing drugs.
Report Highlights
Global Insight Service's, Graft Versus Host Disease (GVHD) - Drug Pipeline Landscape, 2022 report provides an overview of the Graft Versus Host Disease (GVHD) pipeline drugs. This report covers detailed insights on Graft Versus Host Disease (GVHD) drugs under development, assessment by target, mechanism of action, route of administration and molecule type.Product pipeline by companies, stage of development and key regulatory designations, deals and milestones have been presented to provide insights and thus help industry participants in their decision making. Graft Versus Host Disease (GVHD) pipeline report helps gain insights on drugs which are under development stage of drug development process across globally.
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Methodology
The research process includes extensive secondary research on public domain and other authentic sources to add or update the pipeline products information. The secondary research sources include, but are not limited to company websites, annual reports, financial reports, company pipeline chart, investor presentations and SEC filings, journals and conferences, and clinical trials registries.
Scope
The pipeline landscape report provides analysis of pipeline products based on several stages of development ranging from Discovery to Pre-Registration. The report provides a review of pipeline therapeutics by companies based on information derived from company and industry-specific sources. The pipeline report covers assessment of therapeutics by mechanism of action (MoA), drug target, route of administration (RoA) and molecule type. Comprehensive profiles of the pipeline products with details such as company overview, development stage; molecule type, target, mechanism of action, route of administration, dosage form, regulatory designations, key deals, clincial trials, and key upcoming milestones are included.
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Key Players
9 Meters Biopharma Inc
Abbisko Cayman Limited
Accro BioScience (Suzhou) Co Ltd
Actitrexx GmbH
Adienne Pharma & Biotech SA
Alphamab Oncology
AltruBio Inc
Amcyte Pharma Inc
AnaMar AB
AnaptysBio Inc
ASC Therapeutics Inc
AstraZeneca Plc
Avalon GloboCare Corp
Biogen Inc
BioIncept LLC
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