How Does rising R&D Investments Boost Age Related Macular Degeneration?

The worldwide age-related macular degeneration industry has garnered $10,234 million revenue in 2021, and it is projected to rise at a rate of 6.8% from 2021 to 2030, to generate $18,500 million revenue in 2030. It is ascribed to the rising incidence of age-related eye diseases, increasing elderly population, and surging investments in research and development activities.

In addition, the industry is fuelled by growing prevalence of age related macular degeneration, advancements in gene therapies, introduction of robust product pipeline and innovative treatments.

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Furthermore, patents of pupular medicines are expiring, it facilitates players to enhance current formulations. Drugs with lost patent can be manufactured at low cost, making degeneration therapy affordable for people with low-income, and hence fuel the sales of the drugs.

There are only few approved medications in the industry available for treating age related macular degeneration. The associated side effects are harmful to consumer's health. Thus, the demand for safe and novel medications remains unmet for treating this disease.

Numerous pharmaceutical companies focus on advanced gene therapy to treat this condition. The intravitreal injection delivered gene therapy does not impact the cells, it preserves and improves the patients' vision.

These benefits boost the demand for therapy, that positively impacts the industry in the coming future.

Eyelea Category

The eyelea category holds the 50% of industry revenue, led by widespread expansion of the industry and patent protection. The FDA authorized Eyelea is developed to prevent VEGF from functioning in wed AMD. Patients with wet AMD, diabetic macular edema, and macular edema are treated by this drug.

In addition, patients with Beovu report four times higher intraoculat inflammation compared to those get Eyelea treatment. Such elements facilitate people to select Eyelea over Beovu, as a revolutionary medication.

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On the other hand, the Beovu demand is projected to rise at a significant rate in the coming years, led by their higher drying effectiveness, patent protection and successful wet AMD treatment cases.

The wet AMD category holds the significant revenue share in the industry. It is managed by intravitereal injections, of about 22.3 million procedures, executed worldwide in 2017. Around 75% of anti-VEGF injections were utilized in the treatment of wet AMD.

Moreover, branded medications with high prevalence of this condition, caused an increase in the treatments, with growing industry awareness.

Age-related macular degeneration is an eye condition that can cause blurry vision. It usually happens due to macula damage caused by aging. Macula is a part that controls straight and sharp- ahead vision. It is light-sensitive tissue located back of the eye in the retina.

AMD causes vision loss in elderly population. It results in the loss of central vision, that makes it difficult to see faces, drive, read, or perform close-up work such as fixing things or cooking in the house.

The AMD symptoms depend on its stage. Dry AMD usually has 3 stages, early, intermediate, and late. Since, it is a progressive disease, the symptoms are likely to get worst with the time.

● Early dry AMD does not have any symptoms.
● Intermediate dry AMD may have mild symptoms, such as blurriness in central vision, or difficulty in vision in low-lighting.

● Late AMD (wet and dry): In this, most people experience straight lines to appear crooked or wavy. They may also experience blurry area near center vision. Over the time, this blurry area can get bigger or patients may see blank spots.

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