Cell Culture Market to Reach the Value of US$ 27.6 Bn by the End of 2031

Cell Culture Market Outlook 2031

• The global cell culture market was valued at US$ 10.5 Bn in 2020

• It is estimated to expand at a CAGR of 9% from 2021 to 2031

• The global cell culture market is expected to reach the value of US$ 27.6 Bn by the end of 2031

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Leading-edge Cell Culture Products in Demand for Treatment of Chronic Diseases

Advancements in the cell culture market, in terms of innovations in instruments, media, reagents, and sera are benefitting stakeholders in academic institutes, research centers, biotech companies, and pharmaceutical organizations. Launch of advanced cell culture products and demand for novel therapeutics such as biosimilar are expected to boost the growth of the global cell culture market throughout the assessment tenure.

Since cell culture is primarily associated with the diagnosis of infections, testing of new drugs, and other R&D activities, the market is projected to expand at a robust CAGR during the forecast period. The high prevalence of chronic diseases such as cancer, diabetes, renal diseases, and cardiovascular diseases is fueling the demand for cell culture activities to increase the availability of treatment options and therapeutic agents.

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Can Alternatives to Fetal Bovine Serum Transform Cell Culture Market?

Fetal bovine serum (FBS) is commonly used as a serum-supplement for the in vitro cell culture of eukaryotic cells. However, ethical issues pertaining to FBS is affecting research activities in the cell culture market, since fetal bovine serum is derived from the blood drawn from a bovine fetus via a closed system of collection at the slaughterhouse.

Hence, researchers are now resorting to alternatives for FBS such as human AB serum and thrombin-activated platelet-rich plasma to excel in cell culture activities.

Alternatives to FBS are becoming necessary, as, in the past years, advanced therapy medicinal products (ATMP) and cell therapy have become increasingly important in terms of clinical use.

Burgeoning Demand for Biosimilars and Biologic Therapeutics Fueling Market Growth
The high demand for biosimilars and other biologic therapeutics is acting as a key driver for the cell culture market. This is evident since cell culture helps to increase efficiency & productivity and reduce the cost of manufacture for biologic therapeutics.

Healthcare companies are investing in clinical trials to increase the availability of approved biosimilar products. Such advancements are playing an instrumental role in the development of treatment alternatives for chronic diseases in developed as well as developing countries.

Biotech companies are catering to the increase in demand for efficient and cost-effective biosimilars and biologic therapeutics.

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Africa and Middle East Offer Lucrative Growth Opportunities to Companies

Apart from Asia Pacific, companies in the cell culture market are witnessing an increase in the per capita income of individuals in countries of Africa and the Middle East. This improvement in the per capita income can be attributed to rising employment and business opportunities for citizens within the country, and also in countries outside of Africa and the Middle East.

Thus, investments toward the development of the healthcare infrastructure in Africa and the Middle East are benefitting stakeholders in the market for cell culture.

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In many instances, it has been observed that despite having the income for medical treatments, lack of basic healthcare facilities in rural and remote areas of Africa and the Middle East is affecting patient outcomes. In order to improve patient quality of life, companies should set up biotech companies, research institutes, and academic centers in these regions.

These developments are necessary due to high prevalence of rare diseases among the people of Africa and the Middle East.

Cell Culture Market: Overview

• Cell culture is used in a range of applications such as development of model systems for research, analysis of cellular structures & their mechanisms, drug discovery for treatment of diseases such as Alzheimer's, stem cell research, drug evaluation, genetic engineering, and production of biologics such as antibodies,
vaccines, and proteins

• Applications such as stem cell research have significant market potential. Stem cell culture assists in standardization of drug production and enables production of various cell lines and related products.

• Traditional pharmaceutical therapeutics help in treating only disease symptoms, whereas stem cell therapies assist in treating the cause of the disease. Hence, further research in the field of stem cell culture for development of drugs presents an opportunity in the market.

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Rise in Demand for Cell Culture: Major Driver

• Manufacturing of biopharmaceuticals involves use of cell culture systems as a unique method of product development as such products are difficult to be produced by conventional
pharmaceutical development processes

• Research & development in the field of biopharmaceuticals that concentrates on discovery of new therapeutics for rare diseases and new mechanisms of drug actions has increased the scope for cell culture in biologics

• Rise in outsourcing activities and expansion of biopharmaceutical manufacturers are expected to drive the market during the forecast period
Instruments Segment to Dominate Cell Culture Market

• The global cell culture market has been segmented based on product, end-user, and region

• In terms of product, the global cell culture
market has been classified into instruments, media, sera, and reagents. The instruments segment has been split into cell culture vessels (bioreactors), carbon dioxide incubators, biosafety cabinets, cryogenic tanks, and others. The media segment has been segregated into chemically defined, classical media, protein-free media, Lysogeny media, serum-free media, and specialty media. The sera segment has been bifurcated into fetal bovine serum and others. The reagents segment has been split into albumin, amino acid, attachment factors, growth factors & cytokines, protease inhibitor, thrombin, and others.

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• Increase in trend toward the use of animal-derived component-free media and adoption of chemically defined and specialty media is projected to drive the global cell culture market in the near future

• Moreover, automation of cell culture systems demand more sophisticated instruments and equipment. This is anticipated to boost the growth of the instruments segment.
Asia Pacific to Dominate Cell Culture Market
• In terms of region, the global cell culture market has been segmented into North America, Europe, Asia Pacific, Latin America, and Middle East & Africa

• Asia Pacific is expected to dominate the global market during the forecast period. This can be attributed to the adoption of new technologies such as next generation sequencing, higher awareness, increase in healthcare spending in national budgets, early availability of advanced technologies, and higher penetration of research activities across the region.

• Rise in outsourcing activities and expansion of biopharmaceutical manufacturers are projected to drive the market in Asia Pacific during the forecast period. Moreover, low cost of manufacturing in China and India has led to rise in the production facilities, attracting pharmaceutical & biotechnological companies to the region.
Major Players

• Key players operating in the global cell culture market include

o Sartorius AG
o Thermo Fisher Scientific Inc.
o Eppendorf AG
o GE Healthcare
o Corning Incorporated
o Becton
o Dickinson and Company
o Merck KGaA
o Lonza
o VWR International, LLC
o PromoCell GmbH

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