Hypophosphatasia Market Is Expected To Grow During The Forecast Period (2019-2032), DelveInsight | Major Companies- Duke University, Alexion Pharmaceuticals, and Several Others.
DelveInsight's HYPOPHOSPHATASIA Market Insights, Epidemiology, and Market Forecast 2032" report delivers an in-depth understanding of the disease, historical and forecasted epidemiology as well as the HYPOPHOSPHATASIA Market Size and Share in the 7MM (i.e. the United States, EU5 (Germany, Spain, Italy, France, and United Kingdom) and Japan).The HYPOPHOSPHATASIA Market report covers emerging drugs, current treatment practices, market share of individual therapies, and the current forecasted market size from 2019 to 2032. It also evaluates the current treatment practice/algorithm, market drivers & barriers, and unmet medical needs to curate the best opportunities and assess the underlying potential of the market.
HYPOPHOSPHATASIA: An Overview
It is an inherited disorder that affects the overall development of bones and teeth. The condition of Hypophosphatasia disrupts a process called Mineralization, which is critical for the formation of bones that are rigid and strong, and teeth that can chew and grind. Infants Affected with Hypophosphatasia are born with short limbs, an abnormally shaped chest, and soft skull bones. The forms of Hypophosphatasia appearing in childhood or adulthood are less severe than those who are affected as Infants. Affected children may have short stature with bowed legs or knock knees, and enlarged wrist and ankle joints. In adults, chronic pain can be caused due to recurrent fractures in the foot and thigh bones.
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Some of the key highlights of the HYPOPHOSPHATASIA Market Report
Hypophosphatasia is a rare genetic disorder, which causes deformation of teeth and bone, disrupting the process of mineralization which is responsible for the proper bone formation
Hypophosphatasia can manifest itself in a variety of ways, beginning before birth and continuing throughout adulthood.
The severe form of the disorder may occur before birth and sometimes in early infancy
The prevalence of Hypophosphatasia is estimated to be 1/100000 people
In 2015 Food and Drug Administration (FDA) approved a casual enzyme therapy replacement with asfotase-alfa for Hypophosphatasia
HYPOPHOSPHATASIA Market
The HYPOPHOSPHATASIA market size is anticipated to increase during the study period owing to the increasing incident population and rising awareness of the HYPOPHOSPHATASIA Market in the 7MM. The expected launch of emerging therapies and the research and development activities of pharmaceutical companies will also fuel the market growth during the forecast period.
The market outlook section of the report helps to build a detailed comprehension of the historic, current, and forecasted HYPOPHOSPHATASIA Market size by analyzing the impact of current and emerging therapies in the market. It also provides a detailed assessment of the market drivers & barriers, unmet needs, and emerging technologies.
The report gives a thorough detail of the HYPOPHOSPHATASIA Market trend for each marketed drug and late-stage pipeline therapies by evaluating their impact based on the annual cost of therapy, inclusion and exclusion criteria, mechanism of action (MoA), competition with other therapies, brand value, their impact on the market and view of the key opinion leaders.
Hypophosphatasia Symptoms
The symptoms of Hypophosphatasia are clear in the external appearance of the body, some of which include-
Curved (Bowed) arms and legs
A short Body Stature
Babies fail to grow or gain weight as they should normally
Soft, weak, or deformed bones (Rickets)
Wrist and Ankle Bones grow wider than normal
Deformed ribs and chest bones can lead to breathing issues
Key benefits of the HYPOPHOSPHATASIA market report:
Hypophosphatasia market report covers a descriptive overview and comprehensive insight of the Hypophosphatasia Epidemiology and Hypophosphatasia market in the 7MM (the United States, EU5 (Germany, Spain, France, Italy, UK) & Japan.)
The Hypophosphatasia market report provides insights on the current and emerging therapies.
Hypophosphatasia market report provides a global historical and forecasted market covering drug outreach in 7MM.
The Hypophosphatasia market report offers an edge that will help in developing business strategies by understanding trends shaping and driving the Hypophosphatasia market.
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HYPOPHOSPHATASIA Epidemiology
The epidemiology section covers insights into the historical and current HYPOPHOSPHATASIA Market patient pool and forecasted trends for every seven major countries (7MM) from 2019 to 2032. It helps to recognize the causes of current and forecasted trends by exploring numerous studies and views of key opinion leaders. The epidemiology section also provides the diagnosed patient pool and their trends along with assumptions undertaken.
HYPOPHOSPHATASIA Market Drugs & Pipeline Development Activities
The drugs uptake section focuses on the rate of uptake of the potential drugs recently launched in the HYPOPHOSPHATASIA Market or expected to get launched in the market during the study period. The analysis covers HYPOPHOSPHATASIA market uptake by drugs; patient uptake by therapies; and sales of each drug.
Report's Drugs Uptake section helps in understanding the drugs with the most rapid uptake, and the reasons behind the maximal use of new drugs, and allows the comparison of the drugs on the basis of market share and size which again will be useful in investigating factors important in market uptake and in making financial and regulatory decisions.
The report also covers the HYPOPHOSPHATASIA Pipeline Development Activities and provides valuable insights about different therapeutic candidates in Phase II, and Phase III stages and the key companies in the market involved in developing targeted therapeutics. It also analyses recent Development such as collaborations, acquisitions, and mergers, licensing patent details, and other information for emerging therapies. Unmet needs in the HYPOPHOSPHATASIA include therapies that are oral, anthracycline sparing, and deliverable in resource-limited settings. Another major unmet need is the relapse and refractory cases in the patients given treatment with Doxil.
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HYPOPHOSPHATASIA Market Dynamics
The dynamics of the Hypophosphatasia market is anticipated to change in the coming years owing to the expected launch of emerging therapies such as and others during the forecasted period 2018-2030.
HYPOPHOSPHATASIA Companies
Duke University
Alexion Pharmaceuticals
Xcenda, LLC
CENTOGENE GmbH Rostock
Sheffield Teaching Hospitals NHS Foundation Trust
Wuerzburg University Hospital, and Several Others
HYPOPHOSPHATASIA Drugs
Asfotase alfa
ALXN 1850
Whole Genome Sequencing, and Several Others
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Table of content
Key Insights
Executive Summary
Competitive Intelligence Analysis
Market Overview at a Glance
Disease Background and Overview
Patient Journey
Epidemiology and Patient Population
Treatment Algorithm, Current Treatment, and Medical Practices
Unmet Needs
Key Endpoints of HYPOPHOSPHATASIA Market Treatment
Marketed Products
Emerging Therapies
Seven Major Market Analysis
Attribute analysis
7MM: Market Outlook
Access and Reimbursement Overview
KOL Views
Market Drivers
Market Barriers
Appendix
DelveInsight Capabilities
Disclaimer
About DelveInsight
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About DelveInsight
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