RNA-Targeted Small Molecules Market 2021 Size, Growth Analysis Report, Forecast to 2027

The global RNA-targeted small molecules market is anticipated to grow at a significant CAGR during the forecast period (2021-2027). The conventional clinical delivery of oligonucleotide-based therapies comes with certain unaddressed challenges of genetic disorders. This unmet medical need has created promising opportunities for the global RNA-targeted small molecules market. The ability of small molecules to target the more complex RNA structures is primarily anticipated to drive market growth. As of 2020, out of the 55 US FDA-approved drugs, more than 65% of them were small molecule therapeutics; the majority of which were conventionally developed to target proteins.

Although just 2% of the human genome is allegedly responsible for coding proteins. This is why, therapies are now focused on evaluating previously untapped targets, such as non-coding DNA and RNA. For instance, in January 2022, HotSpot Therapeutics and Caris Life Sciences had collaborated to advance precision medicine approaches for HotSpot's emerging product portfolio. The partnership will focus initially on two therapeutic programs, the first of which is HotSpot's novel allosteric inhibitor of the E3 ubiquitin ligase CBL-B, an important target in cancer immunotherapy, spanning from pre-First in Human (FIH) trials through potential Companion Diagnostics (CDx) and launch.

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The global RNA-targeted small molecules market is anticipated to grow at a significant CAGR during the forecast period (2021-2027). The conventional clinical delivery of oligonucleotide-based therapies comes with certain unaddressed challenges of genetic disorders. This unmet medical need has created promising opportunities for the global RNA-targeted small molecules market. The ability of small molecules to target the more complex RNA structures is primarily anticipated to drive market growth. As of 2020, out of the 55 US FDA-approved drugs, more than 65% of them were small molecule therapeutics; the majority of which were conventionally developed to target proteins.

Although just 2% of the human genome is allegedly responsible for coding proteins. This is why, therapies are now focused on evaluating previously untapped targets, such as non-coding DNA and RNA. For instance, in January 2022, HotSpot Therapeutics and Caris Life Sciences had collaborated to advance precision medicine approaches for HotSpot's emerging product portfolio. The partnership will focus initially on two therapeutic programs, the first of which is HotSpot's novel allosteric inhibitor of the E3 ubiquitin ligase CBL-B, an important target in cancer immunotherapy, spanning from pre-First in Human (FIH) trials through potential Companion Diagnostics (CDx) and launch.

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Global RNA Targeted Small Molecules Market Report by Segment

By Product Type

· mRNA Translation Regulation

· RNA Splicing Modification

· Direct RNA Targeting

· Indirect RNA Targeting-Epitranscriptomics

By Application

· Drug Discovery

· Disease Identification

· Oncology Research

By End-User

· Hospitals

· Research Laboratories

· Contract Research Organizations

· Pharmaceutical and Biotechnology Companies

Global RNA Targeted Small Molecules Market by Region

North America

· United States

· Canada

Europe

· UK

· Germany

· Spain

· France

· Italy

· Rest of Europe

Asia-Pacific

· India

· China

· Japan

· South Korea

· Rest of APAC

Rest of the World

· Latin America

· Middle East & Africa

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