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NF-KB Inhibitors Market Report of Top Player like Takeda, Pfizer, Amgen, Apotex Holding, Dr. Reddy’s Laboratories, Teva, Merck, Alkermes, Reata, Catabasis by Growth Factor 2020-2025

10-19-2020 06:37 PM CET | Health & Medicine

Press release from: Business Industry Reports

NF-KB Inhibitors

NF-KB Inhibitors

The report on Global NF-KB Inhibitors Market 2020 includes a study of annual and financial reports of top players, Market Share and Market Size. This research report offers in-depth study of Key Players, Product and Regional Analysis over the forecast period (2020-2025).

Global NF-KB Inhibitors Market overview:

NF-KB (nuclear factor kappa light chain enhancer of activated B cells) is a family of highly conserved transcription factors that regulate much important cellular behaviour, in particular, inflammatory responses, cellular growth and apoptosis. Estrogen and selective estrogen receptor modulators (SERMs) such as raloxifene can act through the estrogen receptor to inhibit NF-KB activation. NSAIDs such as sodium salicylate (aspirin) and sulindac have been reported to inhibit NF-KB activation by inhibiting IκBα phosphorylation. The Global NF-KB Inhibitors Market is segmented on the basis of Product Type, Application, End Use Industry and Region. This report also covers all the regions and countries of the world, which shows a regional development status, including market size.

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On the Basis of Product Type segment, the NF-KB Inhibitors Market is sub segmented into Denosumab, Bortezomib and Others. Based on End Use Industry segment, the NF-KB Inhibitors Market is segmented as Hospital pharmacies, Online pharmacies and Retail pharmacies.

There are several manufacturers of NF-KB Inhibitors in Europe and North America. In North America, the demand for NF-KB Inhibitors is primarily driven by the Healthcare sector. Among the countries in Asia Pacific, the demand was substantially high in developing countries such as China and India.

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Top Industry News:

Merck Presents Three-Year Survival Data for KEYTRUDA (pembrolizumab) in Combination With Chemotherapy and Updated Phase 1/2 Data for Investigational Quavonlimab (MK-1308) in Combination With KEYTRUDA in Advanced Non‑Small Cell Lung Cancer on 16 October, 2020 -- Merck, known as MSD outside the United States and Canada, today announced positive results from two studies from the company’s leading lung cancer clinical development program evaluating KEYTRUDA, Merck’s anti-PD-1 therapy: KEYTRUDA in combination with chemotherapy (KEYNOTE-021 [Cohort G]) and KEYTRUDA in combination with quavonlimab (MK-1308), Merck’s novel investigational anti-CTLA-4 antibody.

In KEYNOTE-021 (Cohort G), first-line treatment with KEYTRUDA in combination with chemotherapy (n=60) demonstrated a significant improvement in objective response rates (58% vs. 33%), progression-free survival (HR=0.54 [95% CI, 0.35-0.83]) and a sustained, long-term survival benefit (HR=0.71 [95% CI, 0.45-1.12]) versus chemotherapy alone (n=63) in patients with advanced nonsquamous non-small cell lung cancer (NSCLC) regardless of PD‑L1 expression (Featured Poster #OFP01.02). Patients in Cohort G had no EGFR or ALK genomic tumor aberrations. These findings represent the longest follow-up data for an anti-PD-1/PD‑L1 therapy in combination with chemotherapy for the first-line treatment of NSCLC. Additionally, updated follow-up data from a Phase 1/2 study of quavonlimab in combination with KEYTRUDA showed encouraging anti-tumor activity and an acceptable safety profile as first-line treatment in patients with advanced NSCLC.

“Over the last five years, KEYTRUDA has become foundational in the treatment of metastatic lung cancer. The long-term data from KEYNOTE-021 (Cohort G) reinforce the use of KEYTRUDA in combination with chemotherapy in certain advanced lung cancer patients, while data from our oncology pipeline reflect our commitment to exploring a number of new combinations with KEYTRUDA that we believe could have a meaningful impact for more lung cancer patients,” said Dr. Vicki Goodman, vice president, oncology clinical research, Merck Research Laboratories. “Updated data from our anti-CTLA-4 antibody quavonlimab in combination with KEYTRUDA support the continued development of this new combination and a Phase 3 study of quavonlimab coformulated with KEYTRUDA in advanced non-small cell lung cancer is planned.”

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Major Key Players:

Some of the NF-KB Inhibitors Market manufacturers involved in the market are Takeda Pharmaceutical Company, Pfizer, Amgen, Apotex Pharmaceutical Holding, Dr. Reddy’s Laboratories, Teva Pharmaceutical, Merck, Alkermes, Reata Pharmaceuticals; Catabasis Pharmaceuticals in World, effective mergers are some of the strategies adopted by the NF-KB Inhibitors Market manufacturers. New product launches and continuous technological innovations are the NF-KB Inhibitors Market strategies adopted by the major players.

Table of Contents:

1 NF-KB Inhibitors Product Definition
2 Global NF-KB Inhibitors Market Manufacturer Share and Market Overview
2.1 Global Manufacturer NF-KB Inhibitors Shipments
2.2 Global Manufacturer NF-KB Inhibitors Business Revenue
2.3 Global NF-KB Inhibitors Market Overview
3 Manufacturer NF-KB Inhibitors Business Introduction
3.1 Takeda Pharmaceutical Company NF-KB Inhibitors Business Introduction
3.1.1 Takeda Pharmaceutical Company NF-KB Inhibitors Shipments, Price, Revenue and Gross profit 2020-2025
3.1.2 Takeda Pharmaceutical Company NF-KB Inhibitors Business Distribution by Region
3.1.3 Takeda Pharmaceutical Company Interview Record
3.1.4 Takeda Pharmaceutical Company NF-KB Inhibitors Business Profile
3.1.5 Takeda Pharmaceutical Company NF-KB Inhibitors Product Specification
3.2 Pfizer NF-KB Inhibitors Business Introduction
3.2.1 Pfizer NF-KB Inhibitors Shipments, Price, Revenue and Gross profit 2020-2025
3.2.2 Pfizer NF-KB Inhibitors Business Distribution by Region
3.2.3 Interview Record
3.2.4 Pfizer NF-KB Inhibitors Business Overview
3.2.5 Pfizer NF-KB Inhibitors Product Specification
3.3 AMGEN NF-KB Inhibitors Business Introduction
3.3.1 AMGEN NF-KB Inhibitors Shipments, Price, Revenue and Gross profit 2020-2025
3.3.2 AMGEN NF-KB Inhibitors Business Distribution by Region
3.3.3 Interview Record
3.3.4 AMGEN NF-KB Inhibitors Business Overview
3.3.5 AMGEN NF-KB Inhibitors Product Specification
3.4 Apotex Pharmaceutical Holding NF-KB Inhibitors Business Introduction
3.5 Dr. Reddy’s Laboratories NF-KB Inhibitors Business Introduction
3.6 Teva Pharmaceutical NF-KB Inhibitors Business Introduction

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