Chronic fatigue syndrome and sick building syndrome may be autoimmune diseases"The role of environmental factors, such as those entailing an immune adjuvant activity, is well established in the pathogenesis of immune mediated diseases. It appears that the activation of the immune system by adjuvants either natural (i.e. infectious agents) or pharmaceutical ones (i.e., vaccines containing alum or silicone), can trigger manifestations of autoimmunity or even autoimmune diseases", Yehuda Shoenfeld and Nancy Agmon-Levin (Tel-Hashomer, Israel) report.
"However, these manifestations are rare, and depend on the adjuvant itself, the genetic susceptibility of the exposed individual, and the rate of diagnosis and reporting of such links.
In recent years several enigmatic conditions, defined by hyperactive immune responses were described.
These conditions, namely siliconosis, the Gulf war syndrome (GWS), the macrophagic myofasciitis syndrome (MMF) and post-vaccination phenomena share a similar complex of signs and symptoms, which suggest a common denominator to each one.
Furthermore, conditions such as the chronic fatigue syndrome, the sick building syndrome as well as defined autoimmune disease may also be linked with similar triggers."
Shoenfeld and Agmon-Levine describe these autoimmune syndroms, induced by adjuvants, in their contribution to the Report on the 10th Dresden Symposium on Autoantibodies held in Dresden 2011.
Conrad, Chan, Fritzler, Humbel, Meroni, Shoenfeld (Eds.) From Prediction to Prevention of Autoimmune Diseases. Pabst, Lengerich/Berlin 2011, 732 pages, ISBN 978-3-89967-735-5
Pabst Science Publishers (Lengerich/Westfalia, Germany) is publishing ten psychological and nine medical journals; furthermore, Pabst is publishing more than hundred psychological and medical books per year – partly specialized scientific literature, partly specialist literature written for laypeople.
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