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Dementia Drugs Market – Increasing number of pipeline products: Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc..,

05-15-2019 06:22 AM CET | Health & Medicine

Press release from: Coherent Market Insights - Pharmaceutical Industry

Dementia Drugs

Dementia Drugs

People suffering from early stage of Alzheimer’s disease with dementia do not have appropriate access to healthcare infrastructure for diagnosis and treatment of the disease. For instance, according to World Alzheimer Report in 2016, only around 50% patients suffering from dementia undergo diagnosis. The rate of underdiagnoses is 10% in low- and middle-income economies. This is expected to propel growth of the dementia drugs market. As of 2011, there were no standard guidelines for diagnosis of disease. Currently, biomarker tests involving amount of beta-amyloid in the brain, which can be visualized in positron emission tomography imaging are under research to diagnosis develop treatment for Alzheimer’s disease.

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As a global push is made for early diagnosis and treatment, the surge in dementia cases will require effective therapies. Manufacturers are increasingly focusing on receiving FDA approvals for their products, in turn boosting market growth. For instance, in September 2017, Zydus Cadila announced that it received a final nod from the U.S. health regulator to market Donepezil Hydrochloride tablets used for the treatment of dementia of the Alzheimer’s type in the U.S.

Various companies are developing novel drugs to strengthen their foothold in the market. For instance, Merck and Company bought an exclusive worldwide license from Japan's Teijin Pharma in 2016, to develop an investigational, preclinical anti-tau antibody, which has disease-modifying potential. Genentech and AC immune are also developing anti-tau antibody. In 2017, TauRx announced phase three results of investigational drug LMTX first tau aggregation inhibitor for Alzheimer’s disease. Moreover, increasing approvals by regulatory agencies is expected to boost market growth.

However, failure of drugs in late stages of clinical trials is the major factor hampering growth of the market. In 2012, Pfizer Inc. and Johnson & Johnson, announced plans to discontinue the development of Alzheimer drug, which was in intravenous (IV) form—bapineuzumab—as drug failed to help patients with memory robbing condition in a second high profile clinical trial. Such failures, deter the expected growth of the market. Dementia market also faces difficulty expanding in certain regions.

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For instance, in the U.K., issues related to cost-effectiveness of cholinesterase inhibitors impelled the Clinical Excellence and National Institute of Health to edge reimbursements to patients with moderate AD. Additionally, they limit the prescriptions of moderate AD valid only through neurologists, which are usually referred to the patients at later disease stage. Thus, use of these drugs are comparatively less in Europe, however, drug-modifying drugs may gain traction in this region in near future.

Some of the top companies operating in the dementia drugs market are Eisai, Inc., Janssen Pharmaceuticals, Inc., Biogen Pharmaceuticals, Forest Laboratories, Inc., Eli Lilly and Company, Novartis AG, Sanofi S.A., AstraZeneca GmbH, F. Hoffmann-La Roche, Merck & Co., Inc.., Valeant Pharmaceutical International, Pfizer Inc., and Teva Pharmaceuticals Industries Ltd.

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Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

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