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Antioxidants May Aid in the Treatment of Tardive Dyskinesia

05-10-2019 09:57 AM CET | Health & Medicine

Press release from: Physicians Postgraduate Press

Memphis, TN (May 9, 2019) – Today, The Primary Care Companion for CNS Disorders published a case report on the use of antioxidants in the treatment of tardive dyskinesia. While new pharmacologic discoveries have occurred in the area of movement disorders, their use comes with a large price tag. Thus, for mild cases, clinicians may want to seek out more cost-effective options. Antioxidants may serve a role in the prevention and treatment of tardive dyskinesia due to the oxidative stress hypothesis.

This case report describes a man in his 30s with a diagnosis of schizoaffective disorder–bipolar type who began exhibiting involuntary movements of the tongue, lips, and truncal area. While initial agents did not completely improve involuntary movements, combining them with antioxidants such as omega-3/DHA/EPA/DPA, vitamin B6, and melatonin lowered symptom severity. Thus, alternative treatment options may be considered before use of more expensive agents for mild cases of tardive dyskinesia.
Access the entire case report, “Antioxidants for the Treatment of Tardive Dyskinesia: AIMing to Find the Best Treatment Option,” by O. Greg Deardorff, PharmD, BCPP; Kimberly A. Ehrhard, PharmD; Jason Cafer, MD; and Beth M. Hall, PharmD, BCPP, at

The Primary Care Companion for CNS Disorders (PCC) is an international, peer-reviewed, online-only journal, published by Physicians Postgraduate Press, Inc. Its mission is to advance the clinical expertise of primary care physicians and other health care professionals who treat patients with mental and neurologic illnesses. PCC is indexed by the National Library of Medicine.

Sallie Gatlin
Physicians Postgraduate Press
PO Box 752870
Memphis, Tennessee 38175-2870
(901) 273-2753

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