Extracorporeal CO2 Removal Market: Adoption over Mechanical Ventilation or as Adjunct to Invasive Mechanical Ventilation to Fuel the Market

The global extracorporeal CO2 removal market is rising with adoption over mechanical ventilation or as an adjunct to invasive mechanical ventilation. The global extracorporeal CO2 removal market was valued at US$ 50 Mn in 2017. It is projected to witness a cumulative annual growth rate (CAGR) of more than 6.0% from 2018 to 2026 to surpass the value of US$ 110 Mn by 2026. The market is expected to witness a high growth owing to higher survival rate of patients through the use of extracorporeal CO2 removal (ECCO2R) life-support machines and favorable medical schemes and reimbursement policies across the globe.

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ECCO2R devices effectively remove carbon dioxide but do not provide significant oxygenation, unlike extracorporeal membrane oxygenation (ECMO) devices. Technically, ECCO2R devices possess certain distinctive characteristics, such as, low blood flow ranging from 350-1000 ml/min, which make them less complex than ECMO devices. ECCO2R devices offer smaller vascular access and infrequent adverse reactions against ECMO.

ECCO2R devices comprises pump console with heater and isolating transformer, offering venovenous and arteriovenous access. However, experimental technique rather than an accepted therapeutic strategy restrain the growth of the extracorporeal co2 removal market. Recent technological advancements have introduced safer, simpler, and more routine ECCO2R applications, such as, durable biocompatible membranes, pumps to permit veno-venous support, wire-reinforced dual-lumen catheters, etc. and highly efficient low-flow device are likely to fuel the extracorporeal CO2 removal market in developed countries. Increase in government expenditure on health care in developed countries is anticipated to drive the extracorporeal co2 removal market during the forecast period.

The global extracorporeal CO2 removal market has been divided into five segments: by product, by application, by access type, by end-user, and by geography. Based on product, the market has been further segmented into extracorporeal CO2 machines and disposables. Between these two, the disposables segment accounted for the dominant market share in 2017. Disposables comprises gas exchange devices and access cannulas which are used per unit per patient. Low price of disposables as compared to that of extracorporeal CO2 machines is likely to contribute to the growth of the disposables segment during the forecast period. The extracorporeal CO2 removal machines segment is expected to grow at a significant rate during the forecast period due to adoption of ECCO2R devices in the treatment of COPD, ARDS, etc. as against ECMO devices and mechanical ventilation.

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Based on application, the global extracorporeal CO2 removal market has been classified into chronic obstructive pulmonary disease (COPD), acute respiratory distress syndrome (ARDS), bridge-to-transplant, and others. The COPD segment accounted for a major share of the global extracorporeal CO2 removal market in 2017, followed by the ARDS segment with a substantial market share. Rise in incidence of respiratory diseases, such as COPD and ARDS, globally is projected to boost the growth of the overall market during the forecast period. In terms of access type, the global extracorporeal CO2 removal market has been bifurcated into venovenous access and arteriovenous access. The venovenous access segment constituted a leading share of the global extracorporeal CO2 removal market in 2017, followed by the arteriovenous segment holding a considerable market share.

Based on end-user, the global extracorporeal CO2 removal market has been segmented into hospitals, surgical centers, and others. The hospitals segment accounted for a major share of the global extracorporeal CO2 removal market in 2017, followed by the surgical centers. Increase in the number of multinational hospitals with advanced laboratory infrastructure is anticipated to propel the hospitals segment during the forecast period.

Geographically, the extracorporeal CO2 removal market has been categorized into four regions: North America, Europe, Asia Pacific, and Rest of the World. North America accounted for the leading share of the global extracorporeal co2 removal market in 2017, followed by Europe. Availability of ECCO2R devices and increase in demand for them have boosted the growth of the market in North America. Asia Pacific is a highly attractive market for ECCO2R devices and is expected to expand at a significant CAGR during the forecast period due to presence of a large patient base in the region, especially in China and India, undergoing chronic obstructive pulmonary disease (COPD), and acute respiratory distress syndrome (ARDS).

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The global extracorporeal CO2 removal market is consolidated with a few companies accounting for a majority of market share. Prominent players operating in the global extracorporeal CO2 removal market include Alung Technologies, Inc., Xenios AG, ESTOR S.P.A, Medtronic Plc., Medica S.P.A., and Getinge Group. These companies exhibit the largest geographical outreach with presence in ECCO2R devices. Demand for technologically advanced ECCO2R devices, along with continuous innovation, is likely to intensify the competition among the top players. Manufacturers are adopting the strategy of acquisition and collaboration to sustain in the market, which are anticipated to lead to high competitive rivalry among them.

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