openPR Logo
Press release

Clinical Trial Studies New Treatment For High-Risk Heart Patients

02-03-2011 09:00 AM CET | Health & Medicine

Press release from: Jennings Online Marketing

/ PR Agency: Jennings
GREENVILLE, NC — Feb. 2, 2011 - A clinical trial under way at the East Carolina Heart Institute is testing the benefit of a new medical device designed to help high-risk people suffering from leaky heart valves.

Dr. W. Randolph Chitwood Jr., director of the Heart Institute and professor of cardiovascular surgery at the Brody School of Medicine at East Carolina University, secured the clinical trial for the MitraClip System for the treatment of mitral valve regurgitation (MR). A serious heart condition, MR can lead to arrhythmias and congestive heart failure if left untreated.

Dr. Curtis Anderson, a cardiothoracic surgeon and assistant professor of cardiovascular sciences, and Dr. Ramesh Daggubati, a cardiologist and clinical professor at Brody, collaborated to perform mitral valve repairs on two patients at Pitt County Memorial Hospital without making the traditional incision in the center of the chest to access the heart. Chitwood joined Drs. Rajasekhar Nekkanti and John Cahill, ECU cardiologists, to assist in the procedure.

In each case, the multidisciplinary team of cardiologists and surgeons placed a thin catheter in the patient’s groin vessel, guided a tiny clip through the heart’s septum and placed the clip between the leaflets of the valve to stop the leak.

“With mitral insufficiency, we normally use the heart/lung machine to either repair or replace the valve,” Chitwood said. “This new procedure is catheter-based, and can be used in high-risk patients who wouldn’t do well on the heart/lung machine. These patients have severe symptoms stemming from the leaky valve and can’t be operated on safely any other way.”

Chitwood said this new procedure “gives the East Carolina Heart Institute an entirely new set of tools for mitral valve repairs in high-risk patients. It is the least invasive way that we can fix a valve. Centers selected to perform these procedures have demonstrated expertise in applying new medical technology under FDA (Food and Drug Administration) guidelines.”

With the clip, patients leave the hospital the next day and within two or three days return to normal activities – or, in many cases, better-than-normal activities.

“Most of the patients are very sick,” said Daggubati, a clinical associate professor of cardiovascular sciences. “Medical management is the only option for them because surgeons consider the risk too high and the patients inoperable.”

Anderson said patient selection is the key to a successful outcome.

“I think a lot of patients with heart failure will be attractive candidates for this device,” he said, adding that collaboration among physicians is vital. “We want patients to have the confidence of knowing that cardiologists and cardiac surgeons are working side by side to give them the best possible outcomes.”

The mitral valve is a one-way valve that connects the left atrium to the left ventricle of the heart. With mitral valve regurgitation, the valve does not seal completely, and blood leaks back into the left atrium. This reversed flow can cause heart and lung damage, as well as death. Symptoms may include an audible heart murmur, shortness of breath and heart palpitations.

For most patients, traditional mitral valve surgery requires an incision in the center of the chest to gain access to the heart valves. The patient must be put on a heart/lung machine and have the valve either repaired or replaced. Patients typically stay in the hospital four to eight days, as well as endure a lengthy recovery.

The patient benefits of the catheter-based techniques are multifaceted, Chitwood said.

“With this catheter-based approach, the patient doesn’t have to go on the heart/lung machine,” he said. “There is less risk of bleeding and fewer lung complications. Efficacy trials have shown that patients improved one to two heart failure classifications, which renders them much more functional.”

One of the patients, a retired 86-year-old farmer from Engelhard, N.C., said he noticed a marked improvement less than two days after the procedure. His daughter said he showed increased physical strength, steadier movements and improved stamina soon after the surgery. The patient said his experience at the Heart Institute “could not have been better.”

Chitwood said with some patients, the mitral valve clip technique led to improvement similar to surgical clinical options. But Chitwood cautioned that the new technique is not suitable for all patients with mitral insufficiency.

This clinical trial, called REALISM, is being administered at medical centers in the U.S. and Canada.

“This is just part of the evolving technology of the East Carolina Heart Institute,” Chitwood said. “We are trying to bring the latest to North Carolina. As we evolve toward less invasive techniques, you’ll see more catheter-based procedures.”

“The idea is to innovate,” he added. “Don’t just do the standard therapy, but innovate and bring something new.”

Chitwood is a pioneer in the development and expansion of robotic-assisted mitral valve repair surgery. Under his leadership, Pitt County Memorial Hospital performed the world’s first endoscopic, minimally invasive mitral replacement in 1996 and the first robotic mitral valve repair using the DaVinci robot in 2000. Since then, Chitwood and his team have developed one of the leading centers in the nation for these procedures, and they continue to provide these advanced procedures to patients from around the U.S.

The East Carolina Heart Institute features a multidisciplinary focus to treat cardiovascular diseases. Both ECU and PCMH have aligned their cardiovascular services under the ECHI by disease processes rather than traditional academic disciplines. This move brings cardiologists, heart surgeons, and vascular surgeons together and increases communication and expertise among caregivers.

About the East Carolina Heart Institute
The East Carolina Heart Institute is a unique partnership that includes University Health Systems Pitt County Memorial Hospital and East Carolina University, along with cardiovascular experts in private practice, academic medicine and research. The East Carolina Heart Institute is the first in North Carolina devoted exclusively to education, research, treatment and prevention of cardiovascular diseases.

Jennings
104-A North Elliott Road
Chapel Hill, NC 27514

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Clinical Trial Studies New Treatment For High-Risk Heart Patients here

News-ID: 161046 • Views: 1324

More Releases from Jennings Online Marketing

Who Let The Dogs In, New Dog Health Resources For Dog Owners
Many owners are choosing to adopt and care for dogs from shelters and other organizations. Among the 10 most popular dog breeds are Labrador Retriever, Golden Retriever, German Shepherd Dog, Beagle, Dachshund, Yorkshire Terrier, Boxer, Poodle, Chihuahua, and Shih Tzu. With this diversity comes unique health problems. The Most Common Dog Health Problems Are: 1. Infections of all kinds. Many dogs suffer some type of infection, with ear
A New Ally In The Fight To Keep Dachshunds And Minature Dachshund Dogs Healthy
When the weather outside is frightful, some dogs need exta tender loving care. Owners of Dachshunds and Miniature Dachshund dogs need to be aware of their pets health needs. Dachshund and Miniature Dachshund owners should take extra care if their low-profile pets come in contact with the snow. Once a Dachshund becomes wet, they no longer have the capacity to stay insullated. Because of their small stature Dachshunds may
Chow Chow Health And Chow Training Secrets Revealed
Chows have health problems that need to be considered when buying. Owners of Chow Chows and Chow puppys need to be aware of their pets unique health needs. Chow Chow owners should take extra care and beware of problems such as hip dysplasia. Chow Chows are also prone to suffer eye irritation called entropion, caused by eyelid abnormality; this can be corrected with surgery. The Most Common Chow Health Problems
Dog Owners Agree That 2006 Will Be The Year Of The Dog
According to the Chinese calendar 2006 will be The Chinese Year Of The Dog. Those born under this sign are said to be honest, quiet, intelligent, generous, stubborn, loyal and faithful to those they love. For some dog lovers that's how they see their pets, and keeping them healthy is a big priority. The past year has seen an increased emphasis on dog health and owners being more proactive in

All 5 Releases


More Releases for Carolina

Carolina Underground Solutions Awarded Veteran Owned Status
Greenville, SC (September 29, 2017) – [CAROLINA UNDERGROUND SOLUTIONS] CUS, a leading underground telecommunications contractor, has received certification from the Department of Veteran Affairs as a registered veteran-owned business. President Brad Cunningham, a Marine Corps veteran stated, “It’s an honor to receive this designation after a lengthy certification process and this is going to assist CUS to expand our efforts with both the private and public sectors”. The company, which
CAROLINA UNDERGROUND SOLUTIONS ACQUIRED
Entrepreneur and Greenville Businessman, Braddock Cunningham, Acquires Carolina Underground Solutions Greenville, SC (May 30, 2017) – [CAROLINA UNDERGROUND SOLUTIONS] CUS, a leading underground telecommunications cabling and conduit contractor, today announced that they have been acquired by Braddock Cunningham, former CEO of Network Controls and Electric, where he grew his company to a South Carolina top 25 fastest growing company 4 times between 2008 and 2013. Cunningham who holds a
Clases de Capoeira en Carolina, Puerto Rico
"Capoeira es un arte marcial brasileiro que disfraza su naturaleza en danza. El arte originó entre esclavos de origen indígena y africanos, y fue instrumental en la abolición de la esclavitud del país." - ArtesMarcialesPR.com “Combat Capoeira”, localizado en la Ave. Roberto Clemente en Carolina, es un programa dedicado a adaptar éste arte marcial a varios elementos de Combate. La clase incluye técnicas de Muay Thai, Jujutsu, entre otras
North Carolina Strawberry Season Begins Soon
Spring's first fruit crop expected to be very good, despite cold winter (Pittsboro, NC) – Strawberries, one of spring's first fruits to ripen, will soon be ready at nearly 200 farms across North Carolina. According to the North Carolina Strawberry Association (NCSA), this year's crop is expected to be early and plentiful. "North Carolina strawberries handled the cold winter well this year, so we're looking forward to a good season," says Debby
GL Solutions Wins North Carolina MMIS Project
GL Solutions announced the awarding of a multi-million dollar contract over five years from North Carolina’s Department of Health and Human Services. This contract employs GL Solutions to develop a new Business Process Automation System (BPAS) for the NC Department of Health and Human Services (DHHS), Office of Medicaid Management Information System Services (OMMISS) and Division of Health Service Regulation (DHSR). DHSR regulates health care facilities and agencies, emergency medical
06-08-2009 | Sports
ClickCulture
ClickCulture Promotes North Carolina Worldwide
Race Team Sponsorship Includes North Carolina Flag Vehicle Wrap RALEIGH, N.C. (June 8, 2009)—ClickCulture Inc. (clickculture.com), a Raleigh-based Web technologies, design and integrated marketing firm, announces today its sponsorship of Creation Autosportif (creationsport.net). The sponsorship includes the North Carolina state flag graphically wrapped on Creation's Le Mans race car. The newly wrapped car will debut at the 77th running of the Le Mans 24 Hour race, held June 13 and 14