openPR Logo
Press release

Mitochondrial Disorders Treatment Market: Healthcare Industry To Remain Key End-Use; Vital Advantages To Boost Demand Through 2026

01-24-2019 01:51 PM CET | Health & Medicine

Press release from: Coherent Market Insights - Pharmaceutical Industry

Global Mitochondrial Disorders Treatment Market

Global Mitochondrial Disorders Treatment Market

Mitochondrial disorders are inherited chronic disorders characterized by a wide range of biochemical and genetic mitochondrial defects and mutations. The disorder affects multiple organs, which includes brain, heart, liver, skeletal muscles, kidney, and respiratory systems. The patients with mitochondrial disorders often suffer from muscle weakness, exercise intolerance, and fatigue due to reduction in mitochondrial respiration, which is caused due to mitochondrial DNA mutations leading to reduced ability to produce cellular adenosine triphosphate (ATP). Despite major advances in understanding of the molecular mechanisms, currently there are no effective treatments for the disease. The treatment of mitochondrial disorders is mostly performed with different vitamins, co-factors, off-label drugs approved for other indications, and nutritional supplements. However, the research organizations and pharmaceutical companies are involved in development of novel drugs with technology advancements including the use of biomarkers, replacement therapies and sophisticated trial designs, thus creating a lucrative opportunity for the market growth.

Download PDF Brochure Of This Research Report @ https://www.coherentmarketinsights.com/insight/request-pdf/1650

Mitochondrial Disorders Treatment Market: Market Dynamics:

Increasing prevalence of mitochondrial disorders causing significant morbidity and mortality combined with the higher potential of genetic transmission to the next generation are the factors driving the market growth. According to the Wellcome Center for Mitochondrial Research, 2015, about 10 people per 100,000 have a mitochondrial disorders, which often express first in early childhood. According to the Genetic and Rare Disease Information Center, women with mitochondrial genetic disorders have 50% chance with each pregnancy of passing along the altered gene to the offspring, thus indicating the rising burden of the disease. Also, the mitochondrial disorders treatment market is expected to gain significant traction in the future, as the pharmaceutical drugs approved for the treatment of primary mitochondrial disease have orphan drug status, thereby having a greater potential for market approval than conventional pharmaceuticals. Moreover, the approval of novel drug molecules from the regulatory agencies is expected to create a lucrative opportunity for the growth of mitochondrial disorders treatment market. For instance, in April 2018, NeuroVive Pharmaceutical AB received orphan drug designation to KL1333 by the US Food and Drug administration (FDA) for the treatment of inherited mitochondrial respiratory chain diseases (MRCD).

Also, the presence of various clinical trials undertaken by various research institutes to address the unmet need of the patients suffering with the mitochondrial disorders is expected to augment market growth. For instance, in April, 2018, GenSight Biologics, a biopharma company focused on discovering and developing innovative gene therapies for retinal neurodegenerative diseases and central nervous system disorders, announced results from the REVERSE Phase III clinical trial evaluating the safety and efficacy of a single intravitreal injection of GS010 (rAAV2/2-ND4) in for treating a mitochondrial disease- Leber Hereditary Optic Neuropathy (LHON).

For In depth Information Get Sample Copy of this Report @ https://www.coherentmarketinsights.com/insight/request-sample/1650

Higher R&D investments by the organizations supporting the researchers for the development of efficient therapies to address the unmet medical needs of the patients is expected to upsurge the growth of mitochondrial disorders treatment market in the near future. For instance, the Foundation for Mitochondrial Medicine (FMM) supports and accelerates the development for most promising mitochondrial research and treatments to treat various forms of mitochondrial disease and disorders by funding targeted therapeutic discovery project. In 2014, (FMM) collaborated with the Michael J. Fox Foundation for Parkinson’s Research (MJFF) to support a research project at the Department of Neuroscience at Mayo Clinic for investigating a mitochondria-targeted therapeutic approach to treating Parkinson’s disease. Also, the United Mitochondria Disease Foundation (UMDF) along with the National Institute of Child Health and Human Development (NICHD) launched the Mitochondrial Disease Sequence Data Resource (MSeqDR) Consortium. The goals of this consortium is to facilitate deposition, curation, annotation and integrated analysis of genomic data for mitochondrial diseases for clinical and research communities.

However, higher R&D cost, stringent regulations for the approval of novel therapies, lack of awareness and understanding of the disease are the factors restraining the market growth.

Mitochondrial Disorders Treatment Market: Regional Dynamics:

Regional segmentation of the global mitochondrial disorders treatment market by Coherent Market Insights comprises North America, Latin America, Europe, Asia Pacific, Middle East, and Africa. North America is expected to hold a dominant position in the global mitochondrial disorders treatment market over the forecast period, owing to increasing prevalence of the disease and the rising number of initiatives to spread awareness and support novel drug development. According to the Institute of Medicine, U.S., 2015, an estimated 30,000 Americans are suffering from inherited defects in their mitochondria. Also, according to the Foundation for Mitochondrial Medicine, an estimated 1,000 children per year are born with some form of mitochondrial disease in the U.S. Moreover, the North American Mitochondrial Disease Consortium (NAMDC), a part of Rare Disease Clinical Research Network (RDCRN), specially works towards collecting information from mitochondrial disease patients in a clinical patient registry, thereby helping researchers to identify and recruit patients for future studies.

Mitochondrial Disorders Treatment Market: Competitive Landscape:

The key players operating in the market are adopting strategic collaborations with research organizations to advance drugs for rare diseases through clinical development. For instance, in February 2018, NeuroVive Pharmaceutical AB in collaboration with Karolinska Institute developed a compound NV556 to treat patients with mitochondrial myopathy. The company is expected to initiate the clinical trials for the compound with the effective outcomes from its preclinical study.

Key players operating in the global mitochondrial disorders treatment market include Centogene AG, GeneDx, Ixchel Pharma, Khondrion BV, Mitobridge, NeuroVive Pharmaceutical AB, Reata Pharmaceuticals Inc., and Stealth Biotherapeutics.

Browse Complete Report For More Information @ https://www.coherentmarketinsights.com/ongoing-insight/mitochondrial-disorders-treatment-market-1650

About Coherent Market Insights:

Coherent Market Insights is a prominent market research and consulting firm offering action-ready syndicated research reports, custom market analysis, consulting services, and competitive analysis through various recommendations related to emerging market trends, technologies, and potential absolute dollar opportunity.

Contact Us:

Mr. Shah
Coherent Market Insights
1001 4th Ave, #3200
Seattle, WA 98154
Tel: +1-206-701-6702
Email: sales@coherentmarketinsights.com

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Mitochondrial Disorders Treatment Market: Healthcare Industry To Remain Key End-Use; Vital Advantages To Boost Demand Through 2026 here

News-ID: 1530343 • Views: 302

More Releases from Coherent Market Insights - Pharmaceutical Industry

Radiopharmaceuticals in Nuclear Medicine Market Advancements to Watch Out For 20 …
Coherent Market Insights released a new market study on 2018-2026 Radiopharmaceuticals Market with 100+ market data Tables, Pie Chat, Graphs & Figures spread through Pages and easy to understand detailed analysis. At present, the market is developing its presence. The Research report presents a complete assessment of the Market and contains a future trend, current growth factors, attentive opinions, facts, and industry validated market data. Ask For Sample Copy of Research
Outsourced Drug Discovery Market: Latest Advancements & Market Outlook 2019 to 2 …
Outsourced drug discovery is a contract-based process, which is conducted by the contract research organizations (CRO) and contract manufacturing organization (CMO). Contract research organization provides support to pharmaceutical, biotechnology, and medical device industries for drug discovery and development. CRO facilitates the various services such as biopharmaceutical development, biologic assay development, preclinical research, clinical trials, and pharmacovigilance, for drug discovery and development. Ask For a Sample Copy of This Business Report @
Cannabis Testing Services Market: New Business Opportunities and Investment Rese …
Cannabis market is highly influenced by rigorous legalization efforts, which are aiming for approval of cannabis for medicinal or recreational purpose. Various governments and regulatory authorities are taking efforts to legalize cannabis, owing to its medicinal benefits. Moreover, commercialization of cannabis-based products under the legalized standards require successful cannabis testing, which further results in lucrative growth opportunity for market players. Ask For a Sample Copy of This Business Report @ https://www.coherentmarketinsights.com/insight/request-sample/2976 Market
Global Myelodysplastic Syndrome (MDS) Treatment Market Balenced To Reach Insigni …
Myelodysplastic syndrome (MDS) is a disorder, which affects the bone marrow and produces immature blood cells. Bone marrow failure leads to lowering the levels of healthy blood cells circulation in the bloodstream. According to Seattle Cancer Care Alliance, around 80%-85% of people with MDS have more cells in their bone marrow than healthy people. According to National Organization for Rare Disorders, MDS deteriorates into a form of cancer in around

All 5 Releases


More Releases for Mitochondria

Full-Scale Mitochondrial Bioenergetics Services at Creative Biogene
As one of the leading bio-companies engaged in mitochondrial research, Creative Biogene, together with its large team of experts, creates a powerful mitochondrial research service platform. To satisfy the research needs of global customers on mitochondrial bioenergies, Creative Biogene provides partners with a comprehensive range of mitochondrial bioenergetics detection and analysis services based on years of experience and high-end instruments. Mitochondria are the primary source of ATP for most cells
ReIgnite Canada - Where to Buy Legit ReIgnite Supplements in Canada?
ReIgnite Canada - ReIgnite supplement is an inventive weight loss pill that addresses the underlying driver of weight gain. Every human cell comprises energy converter organelles called mitochondria. The essential capacity of these organelles is to change over glucose into ATP. The mitochondria make sure your body can burn fat, and assures that your body stays fit as a fiddle. ReIgnite weight loss capsules improve mitochondrial work and enhance weight
MetaboFix - [UK & IRELAND] "Only $147" 3 Months Supply & Reviews!
MetaboFix UK - MetaboFix is a weight-loss supplement that assists grown-ups with shedding fats and boosting metabolic capacity. The supplement comes as a red refreshment. You need to burn through one time each day. It contains nutrients and minerals, alongside homegrown plant extracts. Visit Here and Order the MetaboFix Supplement from the Official Website ==> https://rocklineboost.com/shop-metabofix-uk As indicated by Gold Vida, many eating regimens and weight loss products neglect to accomplish
Cell Structure Probes Market Size, Share, Trends, Regional Analysis and Forecast …
Stratagem Market Insights has announced the addition of the "Cell Structure Probes Market Report 2020-2027 Production, Sales And Consumption Status And Prospects Professional Research", The report classifies the global Cell Structure Probes Market in a precise manner to offer detailed insights about the aspects responsible for augmenting as well as restraining market growth. The cell structure is the most essential part of living organisms that provide basic support organisms. They participate
Mitochondrial-Based Therapeutics to Witness Significant Growth due to Positive C …
According to a new research report “Mitochondrial-Based Therapeutics - Pipeline Analysis 2018, Clinical Trials & Results, Patents, Designations, Collaborations, and Other Developments” published by Pharma Proff, mitochondrial-based therapeutics currently exhibits a strong pipeline with 16 therapeutic candidates. Download the Sample Report @ https://www.pharmaproff.com/request-customization/1212 Mitochondria are the organelles found in cytoplasm of most eukaryotic cells. These are also known as power-house of the cell. Although, the gene expression of mitochondria has been poorly
Mitochondrial Myopathies Market 2018 – Major Competitors: are Reata Pharmaceut …
Mitochondrial myopathy is an umbrella term for rare genetic diseases due to defective mitochondria in cells which results in inability of the mitochondria to consume normal levels of oxygen and produce energy. The disease manifests itself from infancy to adulthood. Although there is no cure for the disease, there have been some research initiatives from pharmaceutical companies. For example, the drug Bendavia of Stealth BioTherapeutics Inc. is undergoing Phase 2 clinical