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PD-1 and PDL-1 Inhibitors Market - Global Industry Insights, Trends, Outlook, and Opportunity Analysis, 2018-2026
PD-1 and PDL-1 Inhibitors Market
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PD-1 inhibitors are effective in treating non-small-cell lung carcinoma (NSCLC), kidney cancer, melanoma of the skin, head and neck cancers, bladder cancer, and Hodgkin lymphoma. Opdivo is leading the race with US$ 3.8 Bn in sales in 2016, compared to US$ 1.4 Bn of Keytruda in 2016. Both these drugs have garnered significant development in past two years with respect to extended therapeutic application and approvals in European countries and Japan.
PDL-1 inhibitors are proven to be effective in NSCLC, bladder cancer, and Merkel cell skin cancer. Avelumab received FDA approval in March 2017 for metastatic Merkel cell carcinoma (MCC), a rare skin cancer with no approved therapies. The drug therefore, received approval under the accelerated approval process, requiring the developers, Pfizer, Inc. and Merck KGaA to conduct larger clinical trials to establish complete safety and efficacy of the drug. The drug is also being tested for bladder cancer, NSCLC, gastric cancer, ovarian cancer, and renal cancer, under the JAVELIN clinical trial program. Extended therapeutic applications widens the potential opportunity for the drugs in the global PD-1 inhibitors and PDL-1 inhibitors market.
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Key Vendors of PD-1 and PDL-1 Inhibitors Market: Pfizer, Inc., Bristol-Myers Squibb, Merck KGaA, AstraZeneca plc, F. Hoffmann-La Roche AG, Merck & Co. Inc., Regeneron Pharmaceuticals, Inc., Novartis AG, and Ono Pharmaceutical Co., Ltd.
The global PD-1 and PDL-1 inhibitors market is segmented based on the drug type and application as follows:
Drug Type
PD-1 inhibitors
- Pembrolizumab (Keytruda)
- Nivolumab (Opdivo)
PDL-1 inhibitors
- Atezolizumab (Tecentriq)
- Avelumab (Bavencio)
Applications
Non-small cell lung cancer
Kidney cancer
Melanoma of the skin
Bladder cancer
Merkel cell skin cancer
Others
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