Deferiprone Market - Size, Share, Outlook, and Forecast till 2026

Deferiprone is an oral drug that functions as an iron chelator and indicated for treatment of thalassemia syndrome. Thalassemia is a form of hereditary anaemia due a defect in oxygen-carrying protein (hemoglobin) production, thus causing impairment in erythropoiesis, the production of new red blood cells. Symptoms associated with thalassemia include fatigue, weakness, paleness, and slow growth. Mild symptoms may not require treatment, however, severe forms require blood transfusions or a donor stem-cell transplant.

Deferiprone is a prescription medication known as an iron chelator, for treatment of high iron levels, especially for people who are required to receive frequent blood transfusions due to a genetic condition.

Deferiprone is indicated for thalassemia syndrome when first line chelation agents are not adequate to treat transfusional iron overload. The drug received license for use in Europe and Asia several years ago, while was awaiting approval in Canada and the U.S. It was approved for use in the U.S. and received FDA approval on October 14, 2011. The approval of the drug in major regions and almost every country of the world, in turn, is expected to increase the accessibility to several patients, thus boosting growth of the Deferiprone market.

Increasing prevalence of thalassemia among the populace is in turn, increasing the demand for Deferiprone drug. This is thus, expected to drive growth of the Deferiprone market.

However, side effects associated with consumption of Deferiprone, such as occurrence of agranulocytosis and neutropenia, which result in fatal infections, as well as hepatoxicity. Patients could also experience adverse effects such as gastrointestinal issues, including diarrhea, ulcer, nausea, and gastrointestinal disturbances. These factors in turn, pose as major restraints for growth of the Deferiprone market.
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Deferiprone works in a simplified manner, as it binds with iron in the blood, further allowing for its excretion through urine, which would otherwise not have been possible through urine. The convenient removal of excess iron in the blood with the help of Deferiprone in turn, is increasing its adoption. Thus, the Deferiprone market is gaining significant traction, globally.
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In May 2018, researchers at Rutgers University and Dartmouth College conducted a pilot study using Deferiprone and found that this is the first oral drug used to treat unrelated HIV eradicated infections, which was able to suppress the virus in patients during treatment and sustained its effects eight weeks from stopping of the treatment. The researchers found that as the topical anti-fungal medicine ciclopirox reactivates the altruistic suicide response of an HIV-infected cell, so does deferiprone work towards killing the HIV DNA it carries.

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