Smoothened Homolog (Protein Gx or SMO) Industry Pipeline Review, H1 2018 - Identify Key Business Opportunities

Overview

Smoothened Homolog (Protein Gx or SMO) - Smoothened homolog (SMO) is a G protein-coupled receptor that probably associates with the patched protein (PTCH) to transduce the hedgehog's proteins signal. Binding of sonic hedgehog (SHH) to its receptor is thought to prevent normal inhibition by patched of smoothened (SMO). It is required for the accumulation of KIF7 and GLI3 in the cilia.

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Report Highlights

It also reviews key players involved in Smoothened Homolog (Protein Gx or SMO) targeted therapeutics development with respective active and dormant or discontinued projects. Currently, The molecules developed by companies in Phase II, Preclinical and Discovery stages are 6, 2 and 1 respectively. Similarly, the universities portfolio in Preclinical and Discovery stages comprises 2 and 1 molecules, respectively. Report covers products from therapy areas Oncology, Genetic Disorders, Gastrointestinal and Undisclosed which include indications Medulloblastoma, Acute Lymphocytic Leukemia (ALL, Acute Lymphoblastic Leukemia), Acute Myelocytic Leukemia (AML, Acute Myeloblastic Leukemia), Adenocarcinoma Of The Gastroesophageal Junction, Basal Cell Carcinoma (Basal Cell Epithelioma), Epithelial Ovarian Cancer, Fallopian Tube Cancer, Gorlin Syndrome (Basal Cell Nevus Syndrome), Myelofibrosis, Peritoneal Cancer, Post-Essential Thrombocythemia Myelofibrosis (Post-ET MF), Post-Polycythemia Vera Myelofibrosis (PPV-MF), Cirrhosis, Colon Cancer, Esophageal Cancer, Leukemias, Meningioma, Metastatic Adenocarcinoma of The Pancreas, Metastatic Hepatocellular Carcinoma (HCC), Myelodysplastic Syndrome, Refractory Multiple Myeloma, Relapsed Multiple Myeloma and Small-Cell Lung Cancer.

 Major Scope of the report:

- The report provides a snapshot of the global therapeutic landscape for Smoothened Homolog (Protein Gx or SMO) 
- The report reviews Smoothened Homolog (Protein Gx or SMO) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources 
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages 
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities 
- The report reviews key players involved in Smoothened Homolog (Protein Gx or SMO) targeted therapeutics and enlists all their major and minor projects 

Table of Contents 

List of Figures 
Introduction 
Global Markets Direct Report Coverage 
Smoothened Homolog (Protein Gx or SMO) - Overview 
Smoothened Homolog (Protein Gx or SMO) - Therapeutics Development 
Products under Development by Stage of Development 
Products under Development by Therapy Area 
Products under Development by Indication 
Products under Development by Companies 
Products under Development by Universities/Institutes 
Smoothened Homolog (Protein Gx or SMO) - Therapeutics Assessment 
Assessment by Mechanism of Action 
Assessment by Route of Administration 
Assessment by Molecule Type 
Smoothened Homolog (Protein Gx or SMO) - Companies Involved in Therapeutics Development 
BeiGene Ltd 
Genentech Inc 
Ignyta Inc 
IMPACT Therapeutics Inc 
Mayne Pharma Group Ltd 
Pfizer Inc 

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