Global Cystic Fibrosis (CF) Market Overview with Detailed Analysis, Competitive landscape Forecast 2023
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Cystic fibrosis is a genetic disease that causes continuous lung infections and breathing problem over time. It is a progressive disease. The presence of imperfect gene causes a thick, sticky buildup of mucus in the lungs, intestine liver, pancreas, and other organs. The mucus in the lungs clogs airways and traps bacteria leading to infections that causes savior lung damage, and respiratory failure. The mucus prevents in the pancreas discharge the digestive enzymes that allow the body to break down food and absorb vital nutrients. This disease is caused by mutation in gene, cystic fibrosis trans membrane conductance regulator (CFTR) is a membrane protein in vertebrates, a protein required for regulating sweat, mucus and body secretions.
The global cystic fibrosis market was sized over USD 2.15 billion in 2015. The global cystic fibrosis market is projected to reach USD 6.67 billion by 2023, growing with a CAGR between 15% and 15.4% from 2017 to 2023. The global market for cystic fibrosis is driven by continued growth of the number of CF patients worldwide. Increasing awareness for cystic fibrosis therapy, technological developments in the R&D and increase in the occurrence of cystic fibrosis are some of the factors likely to drive the global cystic fibrosis market over the forecast period. However, high cost of treatment and R&D, complicated pathophysiology, and increase in genetic mutation rate are the prime restraining factors to the growth of global cystic fibrosis market. Nevertheless, rising number of initiatives taken by nonprofit organizations, and presence of flexible policies are will bring more opportunities to the global cystic fibrosis market over the forecast period.
The report segments the global cystic fibrosis market by drug class, by route of administration and by region. The global cystic fibrosis market is segmented on the basis of drug class as CFTR modulators, mucolytics, pancreatic enzyme supplements and bronchodilators. The CFTR modulator drug class was estimated to account for approximately 44% of total CF drug revenue share in 2015. On the basis of route of administration it is segmented by inhaled drugs and oral drugs. Oral route accounted for the largest share of nearly 62.7% in 2015
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Geographic Coverage and Analysis:
The report provides regional analysis covering geographies such as North America, Europe, Asia-Pacific and Rest of the World. In this section the key trends and market size for each geography is provided over the period of 2015 – 2023. North America is accounted for largest revenue share as a majority of patients affected with CF are of Caucasian descent. The Asia Pacific market region is anticipated to grow at the highest CAGR over the forecast period due to underdiagnosis and lack of country-specific CF patient registries, rising awareness about CF disorders & treatment options is expected to boost this segment over the forecast period.
The companies covered in the report include Vertex Pharmaceuticals Incorporated, Gilead, AbbVie Inc, Novartis AG., F. Hoffmann-La Roche Ltd, Alaxia, Merck & Co. Inc., AIT (Advanced Inhalation Therapies)., ALLERGAN., AstraZeneca, Teva Pharmaceutical Industries Ltd. and Alcresta Therapeutics, Inc.
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