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Ankylosing Spondylitis Therapeutics - Pipeline Review, in-Depth Study on Therapeutics Development, Assessment & Growth of Leading Key Players AbbVie Inc, Sanofi SA, Regeneron Pharmaceuticals Inc
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Companies have conducted clinical trials for evaluating the effectiveness and safety of the drugs. The drugs have shown promising results in treatment of the disease. For example, secukinumab from Novartis AG is in Clinical Phase III, filgotinib from Galapagos NV is in Phase II, IBI303 from Innovent Biologics (Suzhou) Co. Ltd. is in Clinical Phase III, BCD-085 from Biocad Inc. is in Clinical Phase II, certolizumab Pegol from UCB Pharma S.A. is in Clinical Phase III, ixekizumab from Eli Lilly and Company is in Clinical Phase III and brodalumab from Amgen plc is in Clinical Phase II. In April 2017, the drug filgotinib from Galapagos NV in collaboration with Gilead Science Inc., was verified by a proof-of-concept study for the treatment of cutaneous lupus erythematosus. Additionally, filgotinib is in Phase II clinical study, for the treatment of ankylosing spondylitis, Sjögren's syndrome, and psoriatic arthritis. In April 2017, Unichem Laboratories Ltd. received USFDA approval for a pain killer drug, piroxicam, for the inflammatory conditions in ankylosing spondylitis, osteoarthritis and rheumatoid arthritis such as, swelling, stiffness and joint pain.
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Some of the companies having a pipeline of ankylosing spondylitis therapeutics include, AbbVie Inc., Sanofi SA, Centocor Inc., Regeneron Pharmaceuticals Inc., F. Hoffmann-La Roche AG, Janssen Research & Development, LLC, Novartis AG, Amgen plc, Bristol-Myers Squibb Company, Boehringer Ingelheim GmbH, Merck Sharp & Dohme Corp., Galapagos NV, Celgene Corporation, Shanghai Pharmaceuticals Holding Co., Ltd, Innovent Biologics (Suzhou) Co. Ltd., Pfizer Inc., UCB Pharma SA, Eli Lilly and Company, Eisai Co., Ltd., Korea Otsuka Pharmaceutical Co., Ltd., Inflexxion Inc. and Johnson & Johnson Pvt. Ltd.
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