openPR Logo
Press release

Niemann Pick Disease Market Poised for Steady Growth in the Future 2025

12-06-2017 12:32 PM CET | Health & Medicine

Press release from: Transparency Market Research

Niemann Pick Disease Market Poised for Steady Growth in

Niemann-Pick disease (NPC) is a rare advanced genetic cholesterol storage disorder. It is characterized by the body’s inability to transport cholesterol and other fatty substances (lipids) into the cells. Niemann-Pick disease leads to the irregular and harmful accumulation of fatty substances within various tissues of the body, including liver, spleen, and brain tissue. It is an autosomal recessive lysosomal storage disease associated with mutations in NPC1 and NPC2 genes. The disease primarily affects children, with death occurring before or during adolescence but can also onset in later years of life as an adult. Niemann-Pick disease (NPC) is a relatively rare genetic disorder with NPD type A and B affecting 1 in 250,000, and NPD type C affecting 1 in 150,000 live births.However, certain populations may be affected more frequently by NPD. There are five types identified namely type A, type B, type C, type D, and type E. NPD types A and B, also called type I NPD, are caused by low levels of an enzyme called acid sphingomyelinase, which is essential to metabolize a lipid called sphingomyelin. Abnormalities in sphingomyelin metabolization can cause it to accumulate in cells, resulting in organ failure. NPD type A occurs in newborns and mainly affects the brain and liver. Babies with Niemann-Pick disease type A rarely survive past 18 months of age. NPD type B usually develops symptoms in the preteen years and leads to anomalies related to the liver, lung, and spleen. It can lead to frequent lung infections and damaged overall growth.

Report Overview and TOC @ https://www.transparencymarketresearch.com/niemann-pick-disease-market.html

Niemann-Pick disease (NPD) types C and D, also called type II NPD, leads to disruption in the movement of cholesterol between brain cells and can lead to dementia before adolescence. NPD types C and D may appear anytime between infancy and adulthood. NPD types C or D does not affect the spleen and liver much, but brain damage can be extensive. NPD type E occurs in adults and is extremely rare. Symptoms include swelling of the spleen and neurological problems.

The general signs and symptoms associated with NPD include cerebellar ataxia, dysphagia (difficulty in swallowing), dysarthria (slurred speech), tremor, sleep inversion, loss of muscle tone or drop attacks, dystonia, drooping eyes, progressive hearing loss, bipolar disorder, microcephaly (abnormally small head), psychosis, progressive dementia, major and psychotic depression that can include hallucinations, delusions, and mutism.

Request brochure @ https://www.transparencymarketresearch.com/sample/sample.php?flag=B&rep_id=26708

Niemann-Pick disease can be diagnosed by appropriate laboratory tests after the physician determines based on symptoms. The various tests involved are identification of mutations in the NPC1 or NPC2 gene (gene sequencing) and evaluation of the function of the protein or the manifestation of accumulated byproducts (biochemical tests).

There is no cure for type A NPD disease but researchers are constantly working on developing new possible treatments such as enzyme replacement and gene therapy. For Type D, there is no actual treatment; however, palliative care can be provided through some drugs to manage the nervous system symptoms of Type C disease. Increasing funding and research support from private as well as government organizations is expected to yield promising results in the pipeline of Niemann-Pick disease treatment over the next few years. Moreover, technological advancements in gene and enzyme replacement therapy are also anticipated to help in developing effective treatments for this debilitating condition. For instance, Sanofi Genzyme's experimental enzyme-replacement therapy olipudase alfa granted the ‘Breakthrough Therapy’ status has entered the pivotal phase 2/3 trial for adult patients with acid sphingomyelinase deficiency.

for Specific and Customized requirements@ https://www.transparencymarketresearch.com/sample/sample.php?flag=CR&rep_id=26708

Some of the key market players having a therapeutic pipeline for Niemann-Pick disease treatment include Sanofi Genzyme, Aldagen Inc., Alexion Pharmaceuticals, CTD Holdings, Inc., Orphazyme ApS , Actelion Pharmaceuticals Ltd, Vtesse Inc., Merck & Co., Inc., and Okklo Life Sciences BV.

The report offers a comprehensive evaluation of the market. It does so via in-depth qualitative insights, historical data, and verifiable projections about market size. The projections featured in the report have been derived using proven research methodologies and assumptions. By doing so, the research report serves as a repository of analysis and information for every facet of the market, including but not limited to: Regional markets, technology, types, and applications.

Pre Book full report@ https://www.transparencymarketresearch.com/checkout.php?rep_id=26852<ype=S

About TMR

Transparency Market Research (TMR) is a global market intelligence company providing business information reports and services. The company’s exclusive blend of quantitative forecasting and trend analysis provides forward-looking insight for thousands of decision makers. TMR’s experienced team of analysts, researchers, and consultants use proprietary data sources and various tools and techniques to gather and analyze information.

Contact

Transparency Market Research
State Tower
90 State Street,
Suite 700,
Albany NY - 12207
United States
Tel: +1-518-618-1030
USA - Canada Toll Free: 866-552-3453
Email: sales@transparencymarketresearch.com
Website: http://www.transparencymarketresearch.com
TMR Blog: http://www.theglobalhealthnews.com/

This release was published on openPR.

Permanent link to this press release:

Copy
Please set a link in the press area of your homepage to this press release on openPR. openPR disclaims liability for any content contained in this release.

You can edit or delete your press release Niemann Pick Disease Market Poised for Steady Growth in the Future 2025 here

News-ID: 847894 • Views: 85

More Releases from Transparency Market Research

Pre-Printed Paper Rolls Market Demand Analysis and Projected huge Growth by 2027
Pre-printed paper rolls can be a powerful marketing tool for any business. In addition to these pre-printed paper rolls can be used for several applications such as labels, tapes, QR codes, etc. Pre-printed paper rolls are cost-effective and form a brand impression on consumers. Pre-printed paper rolls can be printed in many colors. They are colorful and appealing and are not like ordinary papers. For More Detailed Analysis, Request PDF
Duffle Top Bulk Bags Market Generates Huge Revenue Till 2027- Study By Key Playe …
Duffle top bulk bags made from plastic last long and are highly durable. Duffle top bulk bags are flexible and are strong to carry heavy loads. They have lift straps fixed at the top of the bag, which helps in handling and movement of duffle top bulk bags. Duffle top bulk bags can be of various types, which include opening from the bottom or opening from top. They are lightweight
Multi-Dose Packaging System Market Demand & Future Scope Including Top Players
Medicinal wastage and error in taking proper medication lead to need for multi-dose packaging system. Multi-dose packaging system has various benefits, which includes assisting patients with complicated prescription routines and the ability to enhance patient safety. It provides high-quality, smart packaging and also provides convenience to the patients. Multi-dose packaging system provides consumers with product protection, quality, and patient comfort. It has normal handling, and the formulation present in the
Cargo Belt Market 2020 Growth Rate, Developments in Major Areas, Market Size, Dy …
Globalization leads to the need for transportation of goods over the longer distance. This will drive the demand for cargo belts in the logistics & transportation industry. During the transportation of goods, about one-fourth of the accidents occurred due to poor handling of goods, which can be avoided by using the cargo belt. They are used in light and heavy lorries, trailers trucks, ships, and air crafts. Request PDF Sample For

All 5 Releases


More Releases for NPD

Nitrogen Phosphorus Detector (NPD) Market 2019 | World Market Analysis 2025 | Ma …
Up Market Research has added the latest research report on “Nitrogen Phosphorus Detector (NPD) Market Forecast to 2025” to its huge pool of market research reports database. The most up to date report comprises the latest trends that influence the market competition in the forecast period. The Nitrogen Phosphorus Detector (NPD) Market Report 2025 provides a regional analysis of the market. The regional analysis focuses on manufacturers, suppliers, segmentation according to
GLOBAL NITROGEN PHOSPHORUS DETECTOR (NPD) MARKET INSIGHTS 2019-2025 Rising Deman …
Latest Update "GLOBAL NITROGEN PHOSPHORUS DETECTOR (NPD) MARKET INSIGHTS 2019-2025 Rising Demand, Worldwide Growth" with Edition 2019 Survey of Related Topic (Industries / Pharmaceutical / Retail / Equipments / Energy / ICT) : Global Current Growth and Future. ' ' The Nitrogen Phosphorus Detector (NPD) market was valued at Million US$ in 2018 and is projected to reach Million US$ by 2025, at a CAGR of during the forecast period. In this
Market Research Services Market Emerging Growth Prospects to 2020 by Top Compani …
Market Research Services comprise companies that offers services such as aiding in marketing activities, studying and analyzing the market as per client needs and specifications. The market research services market does not include legal services, accounting, and other major general professional services. The Market Research Services Global Market Briefing provides strategists, marketers and senior management with the critical information they need to assess the market research services sector. Companies Mentioned: Nielsen
New Report on Nitrogen Phosphorus Detector (NPD) Market 2018 Global Analysis By …
The latest report published on Up Market Research, on Nitrogen Phosphorus Detector (NPD) Market Analysis offers comprehensive analysis, delivering detailed market data and penetrating insights. The report covers detailed Nitrogen Phosphorus Detector (NPD) Market analysis by Product, Application, Region, Major Player, Market Size, Share, Trends, Growth and Forecast 2018-2025. Get Free Sample Copy Of This Report @ https://www.upmarketresearch.com/home/requested_sample/3102 The Nitrogen Phosphorus Detector (NPD) Market report published on Up Market Research is spread
Global Nitrogen Phosphorus Detector (NPD) Industry Key Highlights and Major Mark …
A thorough analysis of the global market of Nitrogen Phosphorus Detector can be found in a recent study broadcasted to the mega-repository of Market Research Hub (MRH). The title of the study is “Global Nitrogen Phosphorus Detector (NPD) Industry 2017, Trends and Forecast Report”, which delivers detailed analysis of the world's chief regional market conditions including the product price, profit, capacity, production, capacity utilization, supply, demand and industry growth rate
Latest Research report on Nitrogen Phosphorus Detector (NPD) Market predicts fav …
Report Bazzar has released its latest research-based report entitled ‘Nitrogen Phosphorus Detector (NPD) market.' This comprehensive report provides a holistic approach to the market growth with a detailed and precise analysis of the overall competitive scenario of the Nitrogen Phosphorus Detector (NPD) Market worldwide along with the key trends and latest technologies, playing a prominent role in the Nitrogen Phosphorus Detector (NPD) market growth over the predicted period. It also