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Myocardial Infarction Therapeutics Clinical Trials, Results, Patent & Pipeline Analysis
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Many companies are conducting clinical trials for the development of myocardial infarction pipeline. Shenzhen Salubris Pharmaceuticals Co., Ltd. Has initiated a therapy of Bivalirudin, a thrombin inhibitor along with an anticoagulant in acute myocardial infarction during emergency primary PCI operation. Bayer, Inc. is developing a compound BAY11425 after acute myocardial infarction in patients having left ventricular dysfunction. BAY11425 is currently in Phase II which is being given as a 6 months’ therapy. CSL Behring is developing a compound CSL112 for the treatment of myocardial infarction in patient who also have moderate renal impairment. Some of the major drugs categories that are being given for the treatment of myocardial infarction include, vasodilators, analgesics, antiplatelet agents, b adrenergic blockers, angiotensin converting enzyme inhibitors, angiotensin receptors antagonist, glycoprotein IIb/IIIa inhibitors etc. The other intermediate treatments that are available include aspirin and oxygen therapy. These are some of the initial treatments that are administered to a patient, prior to the other treatments.
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Many institutes, associations and companies are collaborating for the development of therapeutic treatments for myocardial infarction. Eli Lilly and Company collaborated with Centocor, Inc. to conduct clinical trials for efficacy and safety of reteplease and abciximab combination therapy, with abciximab alone administered early or just prior to primary percutaneous coronary intervention.
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Some of the key players having a pipeline of myocardial infarction therapeutics include Pfizer Inc., Novartis N.V., Bristol-Myers Squibb Company, Daiichi Sankyo Company Limited, Boehringer Ingelheim GmbH, AstraZeneca, Apotex Inc., Par Pharmaceutical Companies, Inc., Sandoz, Mylan N.V.
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